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CTP Synthase 1 Is a Novel Therapeutic Target in Lymphoma

HemaSphere, 2023-04, Vol.7 (4), p.e864-n/a

2023

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Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.865-889

2018

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A Phase 1/2 Study of STP938, a First in Class Inhibitor of CTP Synthase 1, in Patients with Relapsed/Refractory B or T Cell Lymphoma

Blood, 2022-11, Vol.140 (Supplement 1), p.12027-12028

2022

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LC-MS/MS Analysis of Bile Acids in In Vitro Samples

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.15

2019

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Population Pharmacokinetic Modeling of Canagliflozin in Healthy Volunteers and Patients with Type 2 Diabetes Mellitus

Clinical pharmacokinetics, 2016-02, Vol.55 (2), p.209-223

2016

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Identification of novel inhibitors of rat Mrp3

European journal of pharmaceutical sciences, 2021-07, Vol.162, p.105813, Article 105813

2021

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Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies

Journal of psychopharmacology (Oxford), 2015-04, Vol.29 (4), p.414-425

2015

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Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures

Archives of toxicology, 2018-06, Vol.92 (6), p.1939-1952

2018

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Population Pharmacokinetics of JNJ-37822681, a Selective Fast-Dissociating Dopamine D2-Receptor Antagonist, in Healthy Subjects and Subjects with Schizophrenia and Dose Selection Based on Simulated D2-Receptor Occupancy

Clinical pharmacokinetics, 2013-11, Vol.52 (11), p.1005-1015

2013

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Population Pharmacokinetics of JNJ-37822681, a Selective Fast-Dissociating Dopamine D^sub 2^-Receptor Antagonist, in Healthy Subjects and Subjects with Schizophrenia and Dose Selection Based on Simulated D^sub 2^-Receptor Occupancy

Clinical pharmacokinetics, 2013-11, Vol.52 (11), p.1005

2013

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Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects

Pain (Amsterdam), 2012-08, Vol.153 (8), p.1648

2012

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Identification of IL-6 as one of the important cytokines responsible for the ability of mononuclear cells to stimulate Sertoli cell functions

Molecular and cellular endocrinology, 1997-09, Vol.132 (1), p.149-160

1997

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Gelatinase A secretion and its control in peritubular and Sertoli cell cultures: effects of hormones, second messengers and inducers of cytokine production

Molecular and cellular endocrinology, 1996-04, Vol.118 (1), p.37-46

1996

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Heregulins or Neu Differentiation Factors and the Interactions between Peritubular Myoid Cells and Sertoli Cells

Endocrinology (Philadelphia), 1999-05, Vol.140 (5), p.2216-2223

1999

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Heregulins or Neu Differentiation Factors and the Interactions between Peritubular Myoid Cells and Sertoli Cells1

Endocrinology (Philadelphia), 1999-05, Vol.140 (5), p.2216-2223

1999

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Cytokines derived from activated human mononuclear cells markedly stimulate transferrin secretion by cultured Sertoli cells

Endocrinology (Philadelphia), 1996-02, Vol.137 (2), p.514-521

1996

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Mesenchymal entactin-1 (nidogen-1) is required for adhesion of peritubular cells of the rat testis in vitro

European journal of cell biology, 2000-02, Vol.79 (2), p.112-120

2000

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Characterization of newly established testicular peritubular and prostatic stromal cell lines: potential use in the study of mesenchymal-epithelial interactions

Endocrinology (Philadelphia), 1995-07, Vol.136 (7), p.2862-2873

1995

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Different cells and cell lines produce factors that modulate Sertoli cell function

Molecular and cellular endocrinology, 1994-05, Vol.101 (1), p.263-275

1994

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CTP Synthase 1 Is a Novel Therapeutic Target in Lymphoma

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

A Phase 1/2 Study of STP938, a First in Class Inhibitor of CTP Synthase 1, in Patients with Relapsed/Refractory B or T Cell Lymphoma

LC-MS/MS Analysis of Bile Acids in In Vitro Samples

Population Pharmacokinetic Modeling of Canagliflozin in Healthy Volunteers and Patients with Type 2 Diabetes Mellitus

Identification of novel inhibitors of rat Mrp3

Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies

Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures

Population Pharmacokinetics of JNJ-37822681, a Selective Fast-Dissociating Dopamine D2-Receptor Antagonist, in Healthy Subjects and Subjects with Schizophrenia and Dose Selection Based on Simulated D2-Receptor Occupancy

Population Pharmacokinetics of JNJ-37822681, a Selective Fast-Dissociating Dopamine D^sub 2^-Receptor Antagonist, in Healthy Subjects and Subjects with Schizophrenia and Dose Selection Based on Simulated D^sub 2^-Receptor Occupancy

Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects

Identification of IL-6 as one of the important cytokines responsible for the ability of mononuclear cells to stimulate Sertoli cell functions

Gelatinase A secretion and its control in peritubular and Sertoli cell cultures: effects of hormones, second messengers and inducers of cytokine production

Heregulins or Neu Differentiation Factors and the Interactions between Peritubular Myoid Cells and Sertoli Cells

Heregulins or Neu Differentiation Factors and the Interactions between Peritubular Myoid Cells and Sertoli Cells1

Cytokines derived from activated human mononuclear cells markedly stimulate transferrin secretion by cultured Sertoli cells

Mesenchymal entactin-1 (nidogen-1) is required for adhesion of peritubular cells of the rat testis in vitro

Characterization of newly established testicular peritubular and prostatic stromal cell lines: potential use in the study of mesenchymal-epithelial interactions

Different cells and cell lines produce factors that modulate Sertoli cell function

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