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Antimicrobial metallopeptides with broad nuclease and ribonuclease activity

Chemical communications (Cambridge, England), 2013-03, Vol.49 (21), p.2118-2120

2013

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Reductive activation of mitomycin C by NADH:cytochrome b5 reductase

Cancer research (Chicago, Ill.), 1993-10, Vol.53 (20), p.4907-4912

1993

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Inhibition of mitochondrial respiration and cyanide-stimulated generation of reactive oxygen species by selected flavonoids

Biochemical pharmacology, 1994-02, Vol.47 (3), p.573-580

1994

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Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3 : Possible relationship to NF-κB

Leukemia, 1997-09, Vol.11 (9), p.1546-1553

1997

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Differential Toxicity of Mitomycin C and Porfiromycin to Aerobic and Hypoxic Chinese Hamster Ovary Cells Overexpressing Human NADPH:Cytochrome c (P-450) Reductase

Proceedings of the National Academy of Sciences - PNAS, 1996-01, Vol.93 (1), p.456-460

1996

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Mitomycin C: a prototype bioreductive agent

Oncology research, 1994, Vol.6 (10-11), p.501

1994

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Identification of Novel and Improved Antimitotic Agents Derived from Noscapine

Journal of medicinal chemistry, 2005-11, Vol.48 (23), p.7096-7098

2005

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Electrochemistry of flavonoids: Relationships between redox potentials, inhibition of mitochondrial respiration, and production of oxygen radicals by flavonoids

Biochemical pharmacology, 1988-07, Vol.37 (13), p.2607-2611

1988

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Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase

Biochemical pharmacology, 1996-06, Vol.51 (12), p.1669-1678

1996

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Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids: A structure-activity study

Biochemical pharmacology, 1986-07, Vol.35 (14), p.2345-2357

1986

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Inhibition of DNA Cross-linking by Mitomycin C by Peroxidase-mediated Oxidation of Mitomycin C Hydroquinone

The Journal of biological chemistry, 2001-09, Vol.276 (37), p.34445-34452

2001

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Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells

Cancer research (Chicago, Ill.), 2001-11, Vol.61 (21), p.7770-7776

2001

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Antimicrobial metallopeptides with broad nuclease and ribonuclease activityElectronic supplementary information (ESI) available. See DOI: 10.1039/c3cc38977d

2013-02

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Mitomycin Resistance in Mammalian Cells Expressing the Bacterial Mitomycin C Resistance Protein MCRA

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (18), p.10489-10494

1999

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Induction of oxidative stress by redox active flavonoids

Advances in experimental medicine and biology, 1998, Vol.439, p.131

1998

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Measurement of Dicumarol-Sensitive NADPH:(Menadione–Cytochrome c) Oxidoreductase Activity Results in an Artifactual Assay of DT-Diaphorase in Cell Sonicates

Analytical biochemistry, 1997-10, Vol.252 (1), p.165-168

1997

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The pH-dependent reduction of Adriamycin catalysed by NADH:cytochrome b5 reductase

Cancer letters, 1994-09, Vol.84 (2), p.149-154

1994

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Inhibition of the mitochondrial NADH-oxidase (NADH-Coenzyme Q oxido-reductase) enzyme system by flavonoids: a structure-activity study

Biochemical pharmacology, 1987-09, Vol.36 (17), p.2873-2874

1987

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Nuclear Localization of NADPH:Cytochrome c (P450) Reductase Enhances the Cytotoxicity of Mitomycin C to Chinese Hamster Ovary Cells

Molecular pharmacology, 2005-02, Vol.67 (2), p.417-423

2005

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The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (11), p.2891-2894

2006

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The intracellular location of NADH:cytochrome b5 reductase modulates the cytotoxicity of the mitomycins to Chinese hamster ovary cells

The Journal of biological chemistry, 1998-04, Vol.273 (15), p.8875

1998

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Pharmaceutical development and manufacturing of a parenteral formulation of a novel antitumor agent, VNP40101M

AAPS PharmSciTech, 2001-08, Vol.2 (3), p.E14-47

2001

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The production of hydroxyl and semiquinone free radicals during the autoxidation of redox active flavonoids

Basic life sciences, 1988, Vol.49, p.149

1988

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Evidence for target site insensitivity to cyanide in Spodoptera eridania larvae

Comparative biochemistry and physiology. C, Comparative pharmacology, 1988, Vol.91 (2), p.469-472

1988

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Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase

Advances in enzyme regulation, 1998-01, Vol.38 (1), p.111-133

1998

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Antimicrobial metallopeptides with broad nuclease and ribonuclease activity

Reductive activation of mitomycin C by NADH:cytochrome b5 reductase

Inhibition of mitochondrial respiration and cyanide-stimulated generation of reactive oxygen species by selected flavonoids

Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3 : Possible relationship to NF-κB

Differential Toxicity of Mitomycin C and Porfiromycin to Aerobic and Hypoxic Chinese Hamster Ovary Cells Overexpressing Human NADPH:Cytochrome c (P-450) Reductase

Mitomycin C: a prototype bioreductive agent

Identification of Novel and Improved Antimitotic Agents Derived from Noscapine

Electrochemistry of flavonoids: Relationships between redox potentials, inhibition of mitochondrial respiration, and production of oxygen radicals by flavonoids

Bioactivation of mitomycin antibiotics by aerobic and hypoxic Chinese hamster ovary cells overexpressing DT-diaphorase

Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids: A structure-activity study

Inhibition of DNA Cross-linking by Mitomycin C by Peroxidase-mediated Oxidation of Mitomycin C Hydroquinone

Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells

Antimicrobial metallopeptides with broad nuclease and ribonuclease activityElectronic supplementary information (ESI) available. See DOI: 10.1039/c3cc38977d

Mitomycin Resistance in Mammalian Cells Expressing the Bacterial Mitomycin C Resistance Protein MCRA

Induction of oxidative stress by redox active flavonoids

Measurement of Dicumarol-Sensitive NADPH:(Menadione–Cytochrome c) Oxidoreductase Activity Results in an Artifactual Assay of DT-Diaphorase in Cell Sonicates

The pH-dependent reduction of Adriamycin catalysed by NADH:cytochrome b5 reductase

Inhibition of the mitochondrial NADH-oxidase (NADH-Coenzyme Q oxido-reductase) enzyme system by flavonoids: a structure-activity study

Nuclear Localization of NADPH:Cytochrome c (P450) Reductase Enhances the Cytotoxicity of Mitomycin C to Chinese Hamster Ovary Cells

The identification of pyrimidine-diazabicyclo[3.3.0]octane derivatives as 5-HT2C receptor agonists

The intracellular location of NADH:cytochrome b5 reductase modulates the cytotoxicity of the mitomycins to Chinese hamster ovary cells

Pharmaceutical development and manufacturing of a parenteral formulation of a novel antitumor agent, VNP40101M

The production of hydroxyl and semiquinone free radicals during the autoxidation of redox active flavonoids

Evidence for target site insensitivity to cyanide in Spodoptera eridania larvae

Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase

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