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Siderophore-Antibiotic Conjugate Design: New Drugs for Bad Bugs?

Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3314

2019

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Bifunctional HDAC Therapeutics: One Drug to Rule Them All?

Molecules (Basel, Switzerland), 2020-09, Vol.25 (19), p.4394

2020

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Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology

PloS one, 2017-03, Vol.12 (3), p.e0172955-e0172955

2017

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Combating Multidrug-Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials

Angewandte Chemie International Edition, 2013-10, Vol.52 (41), p.10706-10733

International ed. in English, 2013

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PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

Chemical communications (Cambridge, England), 2020-04, Vol.56 (32), p.4476-4479

2020

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Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways

Chemical reviews, 2011-01, Vol.111 (1), p.28-67

2011

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Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria

Trends in microbiology (Regular ed.), 2012-09, Vol.20 (9), p.449-458

2012

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Gene activated reinforced scaffolds for SOX9 delivery to enhance repair of large load bearing articular cartilage defects

European cells & materials, 2024-01, Vol.47, p.91-108

2024

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Development of an 'off-the-shelf' gene therapeutic nanoparticle formulation for incorporation into biomaterials for regenerative medicine applications

European cells & materials, 2024-05, Vol.47, p.152-169

2024

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Diversity-Oriented Synthesis of Drug-Like Macrocyclic Scaffolds Using an Orthogonal Organo- and Metal Catalysis Strategy

Angewandte Chemie International Edition, 2014-11, Vol.53 (48), p.13093-13097

International ed. in English, 2014

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Diversity-oriented synthesis of macrocyclic peptidomimetics

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (17), p.6793-6798

2011

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Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (50), p.17743-17748

2014

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Dermal substitute-assisted healing: enhancing stem cell therapy with novel biomaterial design

Archives of Dermatological Research, 2011-07, Vol.303 (5), p.301-315

2011

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2-Heptyl-4-Quinolone, a Precursor of the Pseudomonas Quinolone Signal Molecule, Modulates Swarming Motility in Pseudomonas aeruginosa

Journal of Bacteriology, 2011-12, Vol.193 (23), p.6770-6780

2011

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The design and synthesis of an antibacterial phenothiazine-siderophore conjugate

Beilstein journal of organic chemistry, 2018-10, Vol.14 (1), p.2646-2650

2018

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Development of a 3D-printed bioabsorbable composite scaffold with mechanical properties suitable for treating large, load-bearingarticular cartilage defects

European Cells and Materials, 2023-06, Vol.45, p.158-172

2023

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Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

Beilstein journal of organic chemistry, 2018, Vol.14 (1), p.2680-2688

2018

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Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin

Molecules (Basel, Switzerland), 2013-09, Vol.18 (10), p.11783-11796

2013

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Spatiotemporal dispersion and wave envelopes with relativistic and pseudorelativistic characteristics

Physical review letters, 2012-01, Vol.108 (3), p.034101-034101, Article 034101

2012

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Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells

Beilstein journal of organic chemistry, 2016-07, Vol.12 (1), p.1428-1433

2016

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Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

Journal of medicinal chemistry, 2022-04, Vol.65 (7), p.5642-5659

2022

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Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs)

Biochemistry (Easton), 2023-02, Vol.62 (3), p.645-656

2023

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MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3

ACS medicinal chemistry letters, 2024-01, Vol.15 (1), p.93-98

2024

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A new Pseudomonas quinolone signal (PQS) binding partner: MexG

Chemical science (Cambridge), 2016-04, Vol.7 (4), p.2553-2562

2016

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PROTAC chemical probes for histone deacetylase enzymes

RSC chemical biology, 2023-08, Vol.4 (9), p.623-634

2023

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Siderophore-Antibiotic Conjugate Design: New Drugs for Bad Bugs?

Bifunctional HDAC Therapeutics: One Drug to Rule Them All?

Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology

Combating Multidrug-Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways

Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria

Gene activated reinforced scaffolds for SOX9 delivery to enhance repair of large load bearing articular cartilage defects

Development of an 'off-the-shelf' gene therapeutic nanoparticle formulation for incorporation into biomaterials for regenerative medicine applications

Diversity-Oriented Synthesis of Drug-Like Macrocyclic Scaffolds Using an Orthogonal Organo- and Metal Catalysis Strategy

Diversity-oriented synthesis of macrocyclic peptidomimetics

Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation

Dermal substitute-assisted healing: enhancing stem cell therapy with novel biomaterial design

2-Heptyl-4-Quinolone, a Precursor of the Pseudomonas Quinolone Signal Molecule, Modulates Swarming Motility in Pseudomonas aeruginosa

The design and synthesis of an antibacterial phenothiazine-siderophore conjugate

Development of a 3D-printed bioabsorbable composite scaffold with mechanical properties suitable for treating large, load-bearingarticular cartilage defects

Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products

Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin

Spatiotemporal dispersion and wave envelopes with relativistic and pseudorelativistic characteristics

Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells

Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells

Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs)

MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3

A new Pseudomonas quinolone signal (PQS) binding partner: MexG

PROTAC chemical probes for histone deacetylase enzymes

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