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The role of ubiquitin modification in the regulation of p53

Biochimica et biophysica acta, 2014-01, Vol.1843 (1), p.137-149

2014

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A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

Cell metabolism, 2018-11, Vol.28 (5), p.721-736.e6

2018

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Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

Cell reports (Cambridge), 2020-01, Vol.30 (2), p.481-496.e6

2020

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Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity

Nature structural & molecular biology, 2017-07, Vol.24 (7), p.578-587

2017

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Tumor Suppression by p53: Fall of the Triumvirate?

Cell, 2012-06, Vol.149 (6), p.1183-1185

2012

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Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity

The Journal of biological chemistry, 2014-12, Vol.289 (50), p.34862-34870

2014

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Regulation of p53 stability and function by the deubiquitinating enzyme USP42

The EMBO journal, 2011-12, Vol.30 (24), p.4921-4930

2011

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Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

Nature communications, 2020-04, Vol.11 (1), p.2094-2094, Article 2094

2020

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Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Autophagy, 2014-12, Vol.10 (12), p.2269-2278

2014

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Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

Scientific reports, 2017-05, Vol.7 (1), p.1837-9, Article 1837

2017

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p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant

Cancer & metabolism, 2018-12, Vol.6 (1), p.18-18, Article 18

2018

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iRFP is a real time marker for transformation based assays in high content screening

PloS one, 2014-06, Vol.9 (6), p.e98399

2014

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Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

Nature communications, 2021-01, Vol.12 (1), p.366-366, Article 366

2021

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Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Nature cell biology, 2015-12, Vol.17 (12), p.1556-1568

2015

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Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice

Genes & development, 2021-01, Vol.35 (1-2), p.117-132

2021

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A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo

Science signaling, 2022-02, Vol.15 (720), p.eabd9099

2022

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Corrigendum: Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice

Genes & development, 2021-07, Vol.35 (13-14), p.1071-1071

2021

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iRFP is a sensitive marker for cell number and tumor growth in high-throughput systems

Cell cycle (Georgetown, Tex.), 2014-01, Vol.13 (2), p.220-226

2014

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Small molecules that bind the Mdm2 RING stabilize and activate p53

Carcinogenesis (New York), 2012-04, Vol.33 (4), p.791-798

2012

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Regulation of p53 stability and function by the deubiquitinating enzyme USP42: USP42 targets p53

The EMBO journal, 2011-12, Vol.30 (24), p.4921-4930

2011

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Magnetic resonance cholangiopancreatography at 3 Tesla: Image quality comparison between 3D compressed sensing and 2D single-shot acquisitions

European journal of radiology, 2019-06, Vol.115, p.53-58

2019

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The Ubiquitin Ligase HectH9 Regulates Transcriptional Activation by Myc and Is Essential for Tumor Cell Proliferation

Cell, 2005-11, Vol.123 (3), p.409-421

2005

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Recent warming trends of the Greenland ice sheet documented by historical firn and ice temperature observations and machine learning

The cryosphere, 2024-02, Vol.18 (2), p.609-631

2024

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Acceleration of chemical shift encoding-based water fat MRI for liver proton density fat fraction and T2 mapping using compressed sensing

PloS one, 2019-11, Vol.14 (11), p.e0224988-e0224988

2019

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A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

Science translational medicine, 2016-03, Vol.8 (328), p.328ra30

2016

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The role of ubiquitin modification in the regulation of p53

A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3

Cancer-Specific Loss of p53 Leads to a Modulation of Myeloid and T Cell Responses

Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity

Tumor Suppression by p53: Fall of the Triumvirate?

Ubiquitin-specific Peptidase 42 (USP42) Functions to Deubiquitylate Histones and Regulate Transcriptional Activity

Regulation of p53 stability and function by the deubiquitinating enzyme USP42

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity

Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo

p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant

iRFP is a real time marker for transformation based assays in high content screening

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice

A noninvasive iRFP713 p53 reporter reveals dynamic p53 activity in response to irradiation and liver regeneration in vivo

Corrigendum: Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice

iRFP is a sensitive marker for cell number and tumor growth in high-throughput systems

Small molecules that bind the Mdm2 RING stabilize and activate p53

Regulation of p53 stability and function by the deubiquitinating enzyme USP42: USP42 targets p53

Magnetic resonance cholangiopancreatography at 3 Tesla: Image quality comparison between 3D compressed sensing and 2D single-shot acquisitions

The Ubiquitin Ligase HectH9 Regulates Transcriptional Activation by Myc and Is Essential for Tumor Cell Proliferation

Recent warming trends of the Greenland ice sheet documented by historical firn and ice temperature observations and machine learning

Acceleration of chemical shift encoding-based water fat MRI for liver proton density fat fraction and T2 mapping using compressed sensing

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

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