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Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Scientific reports, 2016-07, Vol.6 (1), p.30093-30093, Article 30093

2016

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Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin

Molecules (Basel, Switzerland), 2017-03, Vol.22 (3), p.462

2017

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Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma

Scientific reports, 2018-09, Vol.8 (1), p.14294-13, Article 14294

2018

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Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma

Molecular cancer therapeutics, 2010-03, Vol.9 (3), p.731-741

2010

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Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation

Cell communication and signaling, 2019-03, Vol.17 (1), p.25-25, Article 25

2019

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The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

Molecular cancer, 2010-06, Vol.9 (1), p.162-162, Article 162

2010

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LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

Journal of the American Academy of Orthopaedic Surgeons, 2019-11, Vol.27 (22), p.841

2019

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The Wnt signaling pathway: implications for therapy in osteosarcoma

Expert review of anticancer therapy, 2011-08, Vol.11 (8), p.1223-1232

2011

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Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma

Translational oncology, 2020-10, Vol.13 (10), p.100809-100809, Article 100809

2020

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Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (21), p.9762-9770

2005

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Prognostic and Therapeutic Utility of Variably Expressed Cell Surface Receptors in Osteosarcoma

Sarcoma, 2021, Vol.2021, p.8324348-10

2021

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Osteosarcoma: Basic Science and Clinical Implications

The Orthopedic clinics of North America, 2006, Vol.37 (1), p.1-7

2006

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Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells

Journal of orthopaedic research, 2007-07, Vol.25 (7), p.964-971

2007

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Messenger RNA Expression Levels of CXCR4 Correlate with Metastatic Behavior and Outcome in Patients with Osteosarcoma

Clinical cancer research, 2005-04, Vol.11 (7), p.2561-2567

2005

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Expression of LDL receptor‐related protein 5 (LRP5) as a novel marker for disease progression in high‐grade osteosarcoma

International journal of cancer, 2004-03, Vol.109 (1), p.106-111

2004

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Analysis of prognostic factors in Ewing sarcoma using a population‐based cancer registry

Cancer, 2010-04, Vol.116 (8), p.1964-1973

2010

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Wnt signaling in osteosarcoma

Advances in experimental medicine and biology, 2014, Vol.804, p.33

2014

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LRP5 Signaling in Osteosarcomagenesis: a Cautionary Tale of Translation from Cell Lines to Tumors

Translational oncology, 2016-10, Vol.9 (5), p.438-444

2016

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Upfront surgical resection for primary bone tumors: rationale and potential benefits

Surgical and experimental pathology, 2020-02, Vol.3 (1), p.1-10, Article 5

2020

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Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis

Molecular cancer, 2013-06, Vol.12 (1), p.55-55, Article 55

2013

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The effect of simulated metastatic lytic lesions on proximal femoral strength

Clinical orthopaedics and related research, 2007-06, Vol.459 (459), p.139-145

2007

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Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma

Oncogene, 2024-03, Vol.43 (13), p.962-975

2024

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Elevated Physiologic Tumor Pressure Promotes Proliferation and Chemosensitivity in Human Osteosarcoma

Clinical cancer research, 2005-03, Vol.11 (6), p.2389-2397

2005

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SKP2 Knockout in Rb1/p53-Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis

Molecular cancer therapeutics, 2024-02, Vol.23 (2), p.223

2024

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HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival

Scientific reports, 2016-08, Vol.6 (1), p.31154-31154, Article 31154

2016

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Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin

Down-regulation of Skp2 expression inhibits invasion and lung metastasis in osteosarcoma

Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma

Flavokawain B targets protein neddylation for enhancing the anti-prostate cancer effect of Bortezomib via Skp2 degradation

The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

LigaSure Use Decreases Intraoperative Blood Loss Volume and Blood Transfusion Volume in Sarcoma Surgery

The Wnt signaling pathway: implications for therapy in osteosarcoma

Skp2 depletion reduces tumor-initiating properties and promotes apoptosis in synovial sarcoma

Expression of Frzb/secreted Frizzled-related protein 3, a secreted Wnt antagonist, in human androgen-independent prostate cancer PC-3 cells suppresses tumor growth and cellular invasiveness

Prognostic and Therapeutic Utility of Variably Expressed Cell Surface Receptors in Osteosarcoma

Osteosarcoma: Basic Science and Clinical Implications

Blocking Wnt/LRP5 signaling by a soluble receptor modulates the epithelial to mesenchymal transition and suppresses met and metalloproteinases in osteosarcoma Saos-2 cells

Messenger RNA Expression Levels of CXCR4 Correlate with Metastatic Behavior and Outcome in Patients with Osteosarcoma

Expression of LDL receptor‐related protein 5 (LRP5) as a novel marker for disease progression in high‐grade osteosarcoma

Analysis of prognostic factors in Ewing sarcoma using a population‐based cancer registry

Wnt signaling in osteosarcoma

LRP5 Signaling in Osteosarcomagenesis: a Cautionary Tale of Translation from Cell Lines to Tumors

Upfront surgical resection for primary bone tumors: rationale and potential benefits

Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis

The effect of simulated metastatic lytic lesions on proximal femoral strength

Targeted inhibition of SCFSKP2 confers anti-tumor activities resulting in a survival benefit in osteosarcoma

Elevated Physiologic Tumor Pressure Promotes Proliferation and Chemosensitivity in Human Osteosarcoma

SKP2 Knockout in Rb1/p53-Deficient Mouse Models of Osteosarcoma Induces Immune Infiltration and Drives a Transcriptional Program with a Favorable Prognosis

HHLA2, a member of the B7 family, is expressed in human osteosarcoma and is associated with metastases and worse survival

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