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Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

Cell reports (Cambridge), 2021-06, Vol.35 (11), p.109246-109246, Article 109246

2021

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Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1417-1421

2015

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Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

PloS one, 2023-03, Vol.18 (3), p.e0279335

2023

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GPCR-Mediated Signaling of Metabolites

Cell metabolism, 2017-04, Vol.25 (4), p.777-796

2017

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Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

Molecular metabolism (Germany), 2017-12, Vol.6 (12), p.1585-1596

2017

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Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

Molecular metabolism (Germany), 2021-07, Vol.49, p.101207-101207, Article 101207

2021

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Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

Metabolites, 2021-06, Vol.11 (7), p.411

2021

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The Existence of Multiple Conformers of Interleukin-21 Directs Engineering of a Superpotent Analogue

The Journal of biological chemistry, 2007-08, Vol.282 (32), p.23326-23336

2007

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Crystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21R

The Journal of biological chemistry, 2012-03, Vol.287 (12), p.9454-9460

2012

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Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

Science signaling, 2023-04, Vol.16 (779), p.eabl4283

2023

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The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

Molecular metabolism (Germany), 2019-01, Vol.19, p.49-64

2019

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Constitutive Activation of Tethered-Peptide/Corticotropin-Releasing Factor Receptor Chimeras

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (18), p.10277-10281

2000

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Rational Design of Interleukin-21 Antagonist through Selective Elimination of the γC Binding Epitope

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.12223-12231

2010

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Binding of Norbinaltorphimine (norBNI) Congeners to Wild-Type and Mutant Mu and Kappa Opioid Receptors: Molecular Recognition Loci for the Pharmacophore and Address Components of Kappa Antagonists

Journal of medicinal chemistry, 2000-04, Vol.43 (8), p.1573-1576

2000

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CS16-3. The extracellular domains of the IL-21 receptor are bridged by glycosylation through conserved anchor points

Cytokine (Philadelphia, Pa.), 2011-10, Vol.56 (1), p.105-105

2011

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Mutational Evidence for a Common κ Antagonist Binding Pocket in the Wild-Type κ and Mutant μ[K303E] Opioid Receptors

Journal of medicinal chemistry, 1998-12, Vol.41 (25), p.4911-4914

1998

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Constitutive Activity of Glucagon Receptor Mutants

Molecular endocrinology (Baltimore, Md.), 1998-01, Vol.12 (1), p.78-86

1998

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Differentiation Between Binding Sites for Angiotensin II and Nonpeptide Antagonists on the Angiotensin II Type 1 Receptors

Proceedings of the National Academy of Sciences - PNAS, 1994-07, Vol.91 (15), p.7046-7050

1994

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Steric Hindrance Mutagenesis versus Alanine Scan in Mapping of Ligand Binding Sites in the Tachykinin NK1 Receptor

Molecular pharmacology, 1998-01, Vol.53 (1), p.166

1998

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Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes

Regulatory peptides, 2004-07, Vol.119 (3), p.151-154

2004

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Dual Agonistic and Antagonistic Property of Nonpeptide Angiotensin AT1 Ligands: Susceptibility to Receptor Mutations

Molecular pharmacology, 1997-02, Vol.51 (2), p.301-311

1997

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Ligand Binding Pocket of the Human Somatostatin Receptor 5: Mutational Analysis of the Extracellular Domains

Molecular pharmacology, 1997-11, Vol.52 (5), p.807-814

1997

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Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants

Canadian journal of physiology and pharmacology, 2002-05, Vol.80 (5), p.413

2002

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Rational Design of Interleukin-21 Antagonist through Selective Elimination of the gC Binding Epitope

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.12223-12231

2010

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Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

Cutting Edge: identification of neutrophil PGLYRP1 as a ligand for TREM-1

Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

GPCR-Mediated Signaling of Metabolites

Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist

Disruption of GPR35 Signaling in Bone Marrow-Derived Cells Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

The Existence of Multiple Conformers of Interleukin-21 Directs Engineering of a Superpotent Analogue

Crystal Structure of Interleukin-21 Receptor (IL-21R) Bound to IL-21 Reveals That Sugar Chain Interacting with WSXWS Motif Is Integral Part of IL-21R

Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones

Constitutive Activation of Tethered-Peptide/Corticotropin-Releasing Factor Receptor Chimeras

Rational Design of Interleukin-21 Antagonist through Selective Elimination of the γC Binding Epitope

Binding of Norbinaltorphimine (norBNI) Congeners to Wild-Type and Mutant Mu and Kappa Opioid Receptors: Molecular Recognition Loci for the Pharmacophore and Address Components of Kappa Antagonists

CS16-3. The extracellular domains of the IL-21 receptor are bridged by glycosylation through conserved anchor points

Mutational Evidence for a Common κ Antagonist Binding Pocket in the Wild-Type κ and Mutant μ[K303E] Opioid Receptors

Constitutive Activity of Glucagon Receptor Mutants

Differentiation Between Binding Sites for Angiotensin II and Nonpeptide Antagonists on the Angiotensin II Type 1 Receptors

Steric Hindrance Mutagenesis versus Alanine Scan in Mapping of Ligand Binding Sites in the Tachykinin NK1 Receptor

Typical Danish Caucasian type 2 diabetic patients do not commonly carry genetic variants in GIP and GLP-1 encoding regions of the proGIP and proglucagon genes

Dual Agonistic and Antagonistic Property of Nonpeptide Angiotensin AT1 Ligands: Susceptibility to Receptor Mutations

Ligand Binding Pocket of the Human Somatostatin Receptor 5: Mutational Analysis of the Extracellular Domains

Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

Interaction of a non-peptide agonist with angiotensin II AT1 receptor mutants

Rational Design of Interleukin-21 Antagonist through Selective Elimination of the gC Binding Epitope

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