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Cellular and Molecular Mechanisms of Autoimmune Hepatitis

Annual review of pathology, 2018-01, Vol.13 (1), p.247-292

2018

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The immunogenetics of primary biliary cirrhosis: A comprehensive review

Journal of autoimmunity, 2015-11, Vol.64, p.42-52

2015

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Using GWAS to identify genetic predisposition in hepatic autoimmunity

Journal of autoimmunity, 2016-01, Vol.66, p.25-39

2016

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Making the most of new genetic risk factors – genetic and epigenetic fine mapping of causal autoimmune disease variants

Clinics and research in hepatology and gastroenterology, 2015-09, Vol.39 (4), p.408-411

2015

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High-throughput sequencing analysis of tissue-resident gut and liver B cells reveals antigen-driven clonal expansion in primary sclerosing cholangitis-inflammatory bowel disease

Journal of hepatology, 2017, Vol.66 (1), p.S64-S64

2017

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C-reactive protein and cardiovascular disease: new insights from an old molecule

QJM : An International Journal of Medicine, 2003-11, Vol.96 (11), p.793-807

2003

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Blockade of OX40-OX40L prevents the development of hepatic autoimmunity in a regulatory T cell deficient model

Journal of hepatology, 2017, Vol.66 (1), p.S74-S74

2017

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111 DEVELOPMENT OF A SCORING SYSTEM TO PREDICT RISK OF HEPATOCELLULAR CARCINOMA IN A COHORT OF PATIENTS WITH CIRRHOSIS

Journal of hepatology, 2013-04, Vol.58, p.S49-S49

2013

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921 HEPATIC LYMPHOCYTE IMMUNOPHENOTYPING STUDIES IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS: IL-12 RECEPTOR-b2 EXPRESSION AND INFILTRATING INTRAHEPATIC T-REGULATORY CELLS

Journal of hepatology, 2013-04, Vol.58, p.S380-S380

2013

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O081 : VAP-1 is elevated in PSC, correlates with clinical outcome and exhibits amine oxidase activity in a substrate-dependent manner

Journal of hepatology, 2015-04, Vol.62, p.S231-S231

2015

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P1189 : Decreased serum tweak levels are predictive of adverse outcome in primary sclerosing cholangitis

Journal of hepatology, 2015-04, Vol.62, p.S800-S801

2015

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943 INCREASED FREQUENCY OF CD4+CD28− AND CD8+CD28− T CELL POPULATIONS IN HUMAN PRIMARY SCLEROSING CHOLANGITIS

Journal of hepatology, 2013-04, Vol.58, p.S389-S389

2013

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Dynamic risk prediction in Primary Biliary Cholangitis using the UK-PBC cohort

Journal of hepatology, 2017, Vol.66 (1), p.S547-S548

2017

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Ileo-anal pouch anastomosis negatively impacts graft survival following liver transplantation for primary sclerosing cholangitis

Journal of hepatology, 2017, Vol.66 (1), p.S6-S7

2017

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Proof of efficacy for Seladelpar, a selective PPAR-δ agonist, in patients with primary biliary cholangitis non-responsive to ursodeoxycholic acid: results of an international Phase 2 randomised controlled clinical study

Journal of hepatology, 2017, Vol.66 (1), p.S357-S357

2017

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Exploring the role of macrophages in primary sclerosing cholangitis

Journal of hepatology, 2017, Vol.66 (1), p.S558-S558

2017

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Probing the role of IL-12 in the pathophysiology of primary biliary cholangitis

Journal of hepatology, 2017, Vol.66 (1), p.S363-S363

2017

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Serum LYSYL Oxidase-Like-2 (SLOXL2) Levels Correlate with Disease Severity in Patients with Primary Sclerosing Cholangitis

Journal of hepatology, 2016, Vol.64 (2), p.S428-S428

2016

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P1179 : Connecting the liver and gut in PSC: Intestinal CCL25 is increased in colitis, correlates with inflammatory activity and facilitates effector CCR9+ lymphocyte recruitment

Journal of hepatology, 2015-04, Vol.62, p.S796-S796

2015

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Genome-Wide Association Study (Gwas) of Liver Fibrosis Phenotypes in Patients with Primary Sclerosing Cholangitis (Psc) Reveals Common Genetic Variation Influencing Serum Levels of Lysyl Oxidase-Like-2 (Loxl2)

Journal of hepatology, 2016, Vol.64 (2), p.S180-S181

2016

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Liver-Infiltrating B Cells Produce Autoantibodies that Point toward Novel Autoantigens in Primary Sclerosing Cholangitis

Journal of hepatology, 2016, Vol.64 (2), p.S433-S433

2016

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Cd362+ Human Mesenchymal Stromal Cells Reduce Hepatic Inflammation and Induce M2 Macrophage Polarisation in Murine Models of Primary Sclerosing Cholangitis

Journal of hepatology, 2016, Vol.64 (2), p.S179-S179

2016

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The GLOBE score identifies PBC patients at increased risk of liver transplantation or death in different age-categories over time

Journal of hepatology, 2017, Vol.66 (1), p.S543-S544

2017

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Behavioral Patterns of Total Serum Bilirubin Prior to Major Clinical Endpoints in 3529 Patients with Primary Biliary Cholangitis

Journal of hepatology, 2016, Vol.64 (2), p.S633-S634

2016

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Clarity: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Lopixibat Chloride (Formerly Lum001), a Novel Apical Sodium-Dependent Bile Acid Transporter Inhibitor, in the Treatment of Primary Biliary Cirrhosis Associated with Itching

Journal of hepatology, 2016, Vol.64 (2), p.S197-S197

2016

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Cellular and Molecular Mechanisms of Autoimmune Hepatitis

The immunogenetics of primary biliary cirrhosis: A comprehensive review

Using GWAS to identify genetic predisposition in hepatic autoimmunity

Making the most of new genetic risk factors – genetic and epigenetic fine mapping of causal autoimmune disease variants

High-throughput sequencing analysis of tissue-resident gut and liver B cells reveals antigen-driven clonal expansion in primary sclerosing cholangitis-inflammatory bowel disease

C-reactive protein and cardiovascular disease: new insights from an old molecule

Blockade of OX40-OX40L prevents the development of hepatic autoimmunity in a regulatory T cell deficient model

111 DEVELOPMENT OF A SCORING SYSTEM TO PREDICT RISK OF HEPATOCELLULAR CARCINOMA IN A COHORT OF PATIENTS WITH CIRRHOSIS

921 HEPATIC LYMPHOCYTE IMMUNOPHENOTYPING STUDIES IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS: IL-12 RECEPTOR-b2 EXPRESSION AND INFILTRATING INTRAHEPATIC T-REGULATORY CELLS

O081 : VAP-1 is elevated in PSC, correlates with clinical outcome and exhibits amine oxidase activity in a substrate-dependent manner

P1189 : Decreased serum tweak levels are predictive of adverse outcome in primary sclerosing cholangitis

943 INCREASED FREQUENCY OF CD4+CD28− AND CD8+CD28− T CELL POPULATIONS IN HUMAN PRIMARY SCLEROSING CHOLANGITIS

Dynamic risk prediction in Primary Biliary Cholangitis using the UK-PBC cohort

Ileo-anal pouch anastomosis negatively impacts graft survival following liver transplantation for primary sclerosing cholangitis

Proof of efficacy for Seladelpar, a selective PPAR-δ agonist, in patients with primary biliary cholangitis non-responsive to ursodeoxycholic acid: results of an international Phase 2 randomised controlled clinical study

Exploring the role of macrophages in primary sclerosing cholangitis

Probing the role of IL-12 in the pathophysiology of primary biliary cholangitis

Serum LYSYL Oxidase-Like-2 (SLOXL2) Levels Correlate with Disease Severity in Patients with Primary Sclerosing Cholangitis

P1179 : Connecting the liver and gut in PSC: Intestinal CCL25 is increased in colitis, correlates with inflammatory activity and facilitates effector CCR9+ lymphocyte recruitment

Genome-Wide Association Study (Gwas) of Liver Fibrosis Phenotypes in Patients with Primary Sclerosing Cholangitis (Psc) Reveals Common Genetic Variation Influencing Serum Levels of Lysyl Oxidase-Like-2 (Loxl2)

Liver-Infiltrating B Cells Produce Autoantibodies that Point toward Novel Autoantigens in Primary Sclerosing Cholangitis

Cd362+ Human Mesenchymal Stromal Cells Reduce Hepatic Inflammation and Induce M2 Macrophage Polarisation in Murine Models of Primary Sclerosing Cholangitis

The GLOBE score identifies PBC patients at increased risk of liver transplantation or death in different age-categories over time

Behavioral Patterns of Total Serum Bilirubin Prior to Major Clinical Endpoints in 3529 Patients with Primary Biliary Cholangitis

Clarity: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Lopixibat Chloride (Formerly Lum001), a Novel Apical Sodium-Dependent Bile Acid Transporter Inhibitor, in the Treatment of Primary Biliary Cirrhosis Associated with Itching

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