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Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

Science (American Association for the Advancement of Science), 2010-10, Vol.330 (6002), p.362-366

2010

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Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia

Microbiome, 2021-10, Vol.9 (1), p.210-210, Article 210

2021

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Xenobiotic receptors and the regulation of intestinal homeostasis: harnessing the chemical output of the intestinal microbiota

American journal of physiology: Gastrointestinal and liver physiology, 2022-02, Vol.322 (2), p.G268-G281

2022

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The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

Journal of allergy and clinical immunology, 2012-04, Vol.129 (4), p.1116-1125.e6

2012

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Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis

Nature medicine, 2012-04, Vol.18 (4), p.600-604

2012

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Pregnane X receptor agonists enhance intestinal epithelial wound healing and repair of the intestinal barrier following the induction of experimental colitis

European journal of pharmaceutical sciences, 2014-05, Vol.55, p.12-19

2014

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Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress

Vascular pharmacology, 2018-10, Vol.109, p.56-71

2018

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Understanding the Molecular Mechanisms of Rifaximin in the Treatment of Gastrointestinal Disorders--A Focus on the Modulation of Host Tissue Function

Mini reviews in medicinal chemistry, 2016-01, Vol.16 (3), p.206

Hirota, Simon A

2016

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Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue

PloS one, 2014-10, Vol.9 (10), p.e109087

2014

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Constitutive androstane receptor regulates the intestinal mucosal response to injury

British journal of pharmacology, 2017-06, Vol.174 (12), p.1857-1871

2017

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Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

Gastroenterology (New York, N.Y. 1943), 2010-08, Vol.139 (2), p.542-552.e3

2010

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Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior

Journal of neuroinflammation, 2022-04, Vol.19 (1), p.73-73, Article 73

2022

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The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction

PloS one, 2013-11, Vol.8 (11), p.e81491-e81491

2013

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Protoporphyrin IX derived from dual-species anaerobic biofilms of Fusobacterium necrophorum and Porphyromonas levii attenuates bovine neutrophil function

Biofilm, 2022-12, Vol.4, p.100095-100095, Article 100095

2022

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The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection

Molecular immunology, 2015-02, Vol.63 (2), p.193-202

2015

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Intrarectal Instillation of Clostridium difficile Toxin A Triggers Colonic Inflammation and Tissue Damage: Development of a Novel and Efficient Mouse Model of Clostridium difficile Toxin Exposure

Infection and Immunity, 2012-12, Vol.80 (12), p.4474-4484

2012

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Antibiotic treatment affects the expression levels of copper transporters and the isotopic composition of copper in the colon of mice

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (13), p.5955-5960

2019

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The pregnane X receptor and its microbiota-derived ligand indole 3-propionic acid regulate endothelium-dependent vasodilation

American journal of physiology: endocrinology and metabolism, 2019-08, Vol.317 (2), p.E350-E361

2019

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NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

Inflammatory bowel diseases, 2011-06, Vol.17 (6), p.1359-1372

2011

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Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation

The Journal of pharmacology and experimental therapeutics, 2016-10, Vol.359 (1), p.91

2016

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Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation

Brain, behavior, and immunity, 2022-05, Vol.102, p.266-278

2022

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Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)

Molecular pharmacology, 2021-11, Vol.100 (5), p.428-455

2021

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The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins

The FASEB journal, 2020-02, Vol.34 (2), p.2198-2212

2020

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Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice

Mediators of inflammation, 2016-01, Vol.2016, p.5637685-12

2016

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Behavioural adaptations after antibiotic treatment in male mice are reversed by activation of the aryl hydrocarbon receptor

Brain, behavior, and immunity, 2021-11, Vol.98, p.317-329

2021

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Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia

Xenobiotic receptors and the regulation of intestinal homeostasis: harnessing the chemical output of the intestinal microbiota

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis

Pregnane X receptor agonists enhance intestinal epithelial wound healing and repair of the intestinal barrier following the induction of experimental colitis

Hyperglycaemic impairment of PAR2-mediated vasodilation: Prevention by inhibition of aortic endothelial sodium-glucose-co-Transporter-2 and minimizing oxidative stress

Understanding the Molecular Mechanisms of Rifaximin in the Treatment of Gastrointestinal Disorders--A Focus on the Modulation of Host Tissue Function

Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue

Constitutive androstane receptor regulates the intestinal mucosal response to injury

Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

Recruitment of α4β7 monocytes and neutrophils to the brain in experimental colitis is associated with elevated cytokines and anxiety-like behavior

The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction

Protoporphyrin IX derived from dual-species anaerobic biofilms of Fusobacterium necrophorum and Porphyromonas levii attenuates bovine neutrophil function

The roles of host and pathogen factors and the innate immune response in the pathogenesis of Clostridium difficile infection

Intrarectal Instillation of Clostridium difficile Toxin A Triggers Colonic Inflammation and Tissue Damage: Development of a Novel and Efficient Mouse Model of Clostridium difficile Toxin Exposure

Antibiotic treatment affects the expression levels of copper transporters and the isotopic composition of copper in the colon of mice

The pregnane X receptor and its microbiota-derived ligand indole 3-propionic acid regulate endothelium-dependent vasodilation

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation

Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation

Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)

The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins

Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice

Behavioural adaptations after antibiotic treatment in male mice are reversed by activation of the aryl hydrocarbon receptor

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