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Adjuvant for vaccine immunotherapy of cancer – focusing on Toll‐like receptor 2 and 3 agonists for safely enhancing antitumor immunity

Cancer science, 2015-12, Vol.106 (12), p.1659-1668

2015

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Double-stranded RNA promotes CTL-independent tumor cytolysis mediated by CD11b+Ly6G+ intratumor myeloid cells through the TICAM-1 signaling pathway

Cell death and differentiation, 2016-11, Vol.24 (3), p.385-396

2016

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Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (6), p.2066-2071

2012

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Foxp3+ CD4+ regulatory T cells control dendritic cells in inducing antigen-specific immunity to emerging SARS-CoV-2 antigens

PLoS pathogens, 2021-12, Vol.17 (12), p.e1010085-e1010085

2021

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STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation

Biochemical and biophysical research communications, 2016-09, Vol.478 (4), p.1764-1771

2016

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Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway

The Journal of immunology (1950), 2008-06, Vol.180 (11), p.7175-7183

2008

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The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on Macrophages

PloS one, 2017-01, Vol.12 (1), p.e0169360-e0169360

2017

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Ultraviolet B-Induced Maturation of CD11b-Type Langerin - Dendritic Cells Controls the Expansion of Foxp3 + Regulatory T Cells in the Skin

The Journal of immunology (1950), 2018-01, Vol.200 (1), p.119-129

2018

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Anti-oxidative Amino Acid L-ergothioneine Modulates the Tumor Microenvironment to Facilitate Adjuvant Vaccine Immunotherapy

Frontiers in immunology, 2019-04, Vol.10, p.671

2019

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Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer

Cancer science, 2023-04, Vol.114 (4), p.1256-1269

2023

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IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid

International immunology, 2011-01, Vol.23 (1), p.29-41

2011

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Vaccine immunotherapy with ARNAX induces tumor‐specific memory T cells and durable anti‐tumor immunity in mouse models

Cancer science, 2018-07, Vol.109 (7), p.2119-2129

2018

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Tumor cell death by pattern-sensing of exogenous RNA: Tumor cell TLR3 directly induces necroptosis by poly(I:C) in vivo, independent of immune effector-mediated tumor shrinkage

Oncoimmunology, 2017-10, Vol.6 (10), p.e1078968-e1078968

2017

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Toll‐like receptor 3 signal augments radiation‐induced tumor growth retardation in a murine model

Cancer science, 2018-04, Vol.109 (4), p.956-965

2018

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Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation

The Journal of biological chemistry, 2011-03, Vol.286 (12), p.10702-10711

2011

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Type I Interferon-Independent Dendritic Cell Priming and Antitumor T Cell Activation Induced by a Mycoplasma fermentans Lipopeptide

Frontiers in immunology, 2018-03, Vol.9, p.496-496

2018

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Pattern recognition receptors of innate immunity and their application to tumor immunotherapy

Cancer science, 2010-02, Vol.101 (2), p.313-320

2010

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Live imaging of transforming growth factor‐β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acid

Cancer science, 2016-05, Vol.107 (5), p.644-652

2016

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TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis

Oncoimmunology, 2012-09, Vol.1 (6), p.917-923

2012

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Myeloid-Derived Suppressor Cells Confer Tumor-Suppressive Functions on Natural Killer Cells via Polyinosinic:Polycytidylic Acid Treatment in Mouse Tumor Models

Journal of innate immunity, 2014-01, Vol.6 (3), p.293-305

2014

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TAMable tumor-associated macrophages in response to innate RNA sensing

Oncoimmunology, 2012-09, Vol.1 (6), p.1000-1001

2012

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The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice

Journal of biomedical science, 2017-10, Vol.24 (1), p.79-79, Article 79

2017

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Dynamic regulation of p53 subnuclear localization and senescence by MORC3

Molecular biology of the cell, 2007-05, Vol.18 (5), p.1701-1709

2007

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Development of mouse hepatocyte lines permissive for hepatitis C virus (HCV)

PloS one, 2011-06, Vol.6 (6), p.e21284-e21284

2011

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Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2

Microbes and infection, 2011-04, Vol.13 (4), p.350-358

2011

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Adjuvant for vaccine immunotherapy of cancer – focusing on Toll‐like receptor 2 and 3 agonists for safely enhancing antitumor immunity

Double-stranded RNA promotes CTL-independent tumor cytolysis mediated by CD11b+Ly6G+ intratumor myeloid cells through the TICAM-1 signaling pathway

Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors

Foxp3+ CD4+ regulatory T cells control dendritic cells in inducing antigen-specific immunity to emerging SARS-CoV-2 antigens

STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation

Tumor-Secreted Lactic Acid Promotes IL-23/IL-17 Proinflammatory Pathway

The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on Macrophages

Ultraviolet B-Induced Maturation of CD11b-Type Langerin - Dendritic Cells Controls the Expansion of Foxp3 + Regulatory T Cells in the Skin

Anti-oxidative Amino Acid L-ergothioneine Modulates the Tumor Microenvironment to Facilitate Adjuvant Vaccine Immunotherapy

Mature dendritic cells enriched in regulatory molecules may control regulatory T cells and the prognosis of head and neck cancer

IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid

Vaccine immunotherapy with ARNAX induces tumor‐specific memory T cells and durable anti‐tumor immunity in mouse models

Tumor cell death by pattern-sensing of exogenous RNA: Tumor cell TLR3 directly induces necroptosis by poly(I:C) in vivo, independent of immune effector-mediated tumor shrinkage

Toll‐like receptor 3 signal augments radiation‐induced tumor growth retardation in a murine model

Raftlin Is Involved in the Nucleocapture Complex to Induce Poly(I:C)-mediated TLR3 Activation

Type I Interferon-Independent Dendritic Cell Priming and Antitumor T Cell Activation Induced by a Mycoplasma fermentans Lipopeptide

Pattern recognition receptors of innate immunity and their application to tumor immunotherapy

Live imaging of transforming growth factor‐β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acid

TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosis

Myeloid-Derived Suppressor Cells Confer Tumor-Suppressive Functions on Natural Killer Cells via Polyinosinic:Polycytidylic Acid Treatment in Mouse Tumor Models

TAMable tumor-associated macrophages in response to innate RNA sensing

The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice

Dynamic regulation of p53 subnuclear localization and senescence by MORC3

Development of mouse hepatocyte lines permissive for hepatitis C virus (HCV)

Failure of mycoplasma lipoprotein MALP-2 to induce NK cell activation through dendritic cell TLR2

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