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Chronic ataluren (PTC124) treatment of nonsense mutation cystic fibrosis

The European respiratory journal, 2011-07, Vol.38 (1), p.59-69

2011

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Juxtapapillary retinochoroidal coloboma presenting with macular retinoschisis

Indian journal of ophthalmology, 2022-07, Vol.70 (7), p.2770-2770

2022

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Choroidal flame

Indian journal of ophthalmology, 2022-06, Vol.70 (6), p.1882-1882

2022

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Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial

The Lancet (British edition), 2008-08, Vol.372 (9640), p.719-727

2008

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Changes in confocal microscopy in glaucoma patients after intraocular pressure reduction with medical therapy

Indian journal of ophthalmology, 2024-06, Vol.72 (6), p.881-884

2024

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Circulating tumor DNA as a novel tool to shape clinical trial designs with the potential to impact outcomes: a focus on PI3K inhibitors

Annals of oncology, 2017-11, Vol.28 (11), p.2882-2887

2017

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Discovery and development of novel therapies in advanced breast cancer: rapid development of ribociclib

Annals of oncology, 2017-08, Vol.28 (8), p.2021-2024

2017

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Alpelisib for PIK3CA-Mutated, Hormone Receptor–Positive Advanced Breast Cancer

The New England journal of medicine, 2019-05, Vol.380 (20), p.1929-1940

2019

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Extensive myelinated nerve fibers in eye with colobomatous optic disk

Indian journal of ophthalmology, 2020-10, Vol.68 (10), p.2264-2264

2020

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PI3K inhibitors as new cancer therapeutics: implications for clinical trial design

OncoTargets and therapy, 2016-01, Vol.9 (Issue 1), p.203-210

2016

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Alpelisib (ALP) + fulvestrant (FUL) for advanced breast cancer (ABC): Results of the phase III SOLAR-1 trial

Annals of oncology, 2018-10, Vol.29, p.viii709-viii709

2018

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Quantitative cough assessment in cystic fibrosis (CF)

Journal of cystic fibrosis, 2008-06, Vol.7, p.S59-S59

2008

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G.P.3.05 Phase 2 study of PTC124 for nonsense mutation suppression therapy of Duchenne muscular dystrophy (DMD)

Neuromuscular disorders : NMD, 2007, Vol.17 (9), p.783-783

2007

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PTC124 induces CFTR full-length production and activity in children with nonsense-mutation-mediated CF

Journal of cystic fibrosis, 2008-06, Vol.7, p.S22-S22

2008

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PTC124 treatment over 3 months improves pharmacodynamic and clinical parameters in patients with nonsense-mutation-mediated CF

Journal of cystic fibrosis, 2008-06, Vol.7, p.S22-S22

2008

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Abstract P4-22-16: First-line ribociclib + letrozole in patients with HR+, HER2– advanced breast cancer (ABC) presenting with visceral metastases or bone-only disease: A subgroup analysis of the MONALEESA-2 trial

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P4-P4-22-16

2017

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Abstract P4-22-18: Phase Ib safety, efficacy, and molecular analysis of ribociclib (LEE011) plus letrozole for the treatment of ER+, HER2– advanced breast cancer

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P4-P4-22-18

2017

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Abstract GS2-05: First-line ribociclib vs placebo with goserelin and tamoxifen or a non-steroidal aromatase inhibitor in premenopausal women with hormone receptor-positive, HER2-negative advanced breast cancer: Results from the randomized phase III MONALEESA-7 trial

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.GS2-05-GS2-05

2018

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41 PTC124 activity in CF patients carrying stop mutations: results of a phase 2 study

Journal of cystic fibrosis, 2007, Vol.6, p.S10-S10

2007

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Abstract P4-14-25: Single agent and combined targeting of PI3K, mTOR, HER2 and ER signaling in a panel of HER2+/ER+ versus HER2+/ER- breast cancer cell lines

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P4-P4-14-25

2016

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Abstract OT2-3-08: Phase III randomized study of the oral pan-PI3K inhibitor BKM120 with fulvestrant in postmenopausal women with HR+/HER2– locally advanced or metastatic breast cancer, treated with aromatase inhibitor, and progressed on or after mTOR inhibitor-based treatment – BELLE-3

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (24_Supplement), p.OT2-3-08-OT2-3-08

2012

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Abstract P4-22-05: First-line ribociclib plus letrozole in patients with de novo HR+, HER2– advanced breast cancer (ABC): A subgroup analysis of the MONALEESA-2 trial

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P4-P4-22-05

2017

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Circulating tumor DNA as a novel tool to shape clinical trial designs with the potential to impact outcomes: a focus on PI3K inhibitors

Annals of oncology, 2017-11, Vol.28 (11), p.2882

2017

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Abstract PD1-5: Targeting PI3K overcomes in vivo resistance to everolimus in estrogen receptor (ER+) breast cancer

Cancer research (Chicago, Ill.), 2013-12, Vol.73 (24_Supplement), p.PD1-5-PD1-5

2013

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Abstract P4-08-01: PI3K/mTOR inhibition overcomes in vitro and in vivo trastuzumab resistance independent of feedback activation of pAKT

Cancer research (Chicago, Ill.), 2012-12, Vol.72 (24_Supplement), p.P4-P4-08-01

2012

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Chronic ataluren (PTC124) treatment of nonsense mutation cystic fibrosis

Juxtapapillary retinochoroidal coloboma presenting with macular retinoschisis

Choroidal flame

Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial

Changes in confocal microscopy in glaucoma patients after intraocular pressure reduction with medical therapy

Circulating tumor DNA as a novel tool to shape clinical trial designs with the potential to impact outcomes: a focus on PI3K inhibitors

Discovery and development of novel therapies in advanced breast cancer: rapid development of ribociclib

Alpelisib for PIK3CA-Mutated, Hormone Receptor–Positive Advanced Breast Cancer

Extensive myelinated nerve fibers in eye with colobomatous optic disk

PI3K inhibitors as new cancer therapeutics: implications for clinical trial design

Alpelisib (ALP) + fulvestrant (FUL) for advanced breast cancer (ABC): Results of the phase III SOLAR-1 trial

Quantitative cough assessment in cystic fibrosis (CF)

G.P.3.05 Phase 2 study of PTC124 for nonsense mutation suppression therapy of Duchenne muscular dystrophy (DMD)

PTC124 induces CFTR full-length production and activity in children with nonsense-mutation-mediated CF

PTC124 treatment over 3 months improves pharmacodynamic and clinical parameters in patients with nonsense-mutation-mediated CF

Abstract P4-22-16: First-line ribociclib + letrozole in patients with HR+, HER2– advanced breast cancer (ABC) presenting with visceral metastases or bone-only disease: A subgroup analysis of the MONALEESA-2 trial

Abstract P4-22-18: Phase Ib safety, efficacy, and molecular analysis of ribociclib (LEE011) plus letrozole for the treatment of ER+, HER2– advanced breast cancer

Abstract GS2-05: First-line ribociclib vs placebo with goserelin and tamoxifen or a non-steroidal aromatase inhibitor in premenopausal women with hormone receptor-positive, HER2-negative advanced breast cancer: Results from the randomized phase III MONALEESA-7 trial

41 PTC124 activity in CF patients carrying stop mutations: results of a phase 2 study

Abstract P4-14-25: Single agent and combined targeting of PI3K, mTOR, HER2 and ER signaling in a panel of HER2+/ER+ versus HER2+/ER- breast cancer cell lines

Abstract OT2-3-08: Phase III randomized study of the oral pan-PI3K inhibitor BKM120 with fulvestrant in postmenopausal women with HR+/HER2– locally advanced or metastatic breast cancer, treated with aromatase inhibitor, and progressed on or after mTOR inhibitor-based treatment – BELLE-3

Abstract P4-22-05: First-line ribociclib plus letrozole in patients with de novo HR+, HER2– advanced breast cancer (ABC): A subgroup analysis of the MONALEESA-2 trial

Circulating tumor DNA as a novel tool to shape clinical trial designs with the potential to impact outcomes: a focus on PI3K inhibitors

Abstract PD1-5: Targeting PI3K overcomes in vivo resistance to everolimus in estrogen receptor (ER+) breast cancer

Abstract P4-08-01: PI3K/mTOR inhibition overcomes in vitro and in vivo trastuzumab resistance independent of feedback activation of pAKT

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