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The Tumor Microenvironment Innately Modulates Cancer Progression

Cancer research (Chicago, Ill.), 2019-09, Vol.79 (18), p.4557-4566

2019

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Merlin deficiency alters the redox management program in breast cancer

Molecular oncology, 2021-04, Vol.15 (4), p.942-956

2021

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Ribosome biosynthesis and Hedgehog activity are cooperative actionable signaling mechanisms in breast cancer following radiotherapy

NPJ precision oncology, 2023-06, Vol.7 (1), p.61-61, Article 61

2023

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Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages

Cancer research (Chicago, Ill.), 2021-11, Vol.81 (21), p.5425-5437

2021

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A Metabolic Axis of Immune Intractability

Cancer immunology research, 2024-03, Vol.12 (3), p.282

2024

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Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma

Laboratory investigation, 2022-11, Vol.102 (11), p.1236-1244

2022

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Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study

Journal of clinical oncology, 2023-11, Vol.41 (33), p.JCO2300702-5150

2023

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Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding

Cancer letters, 2021-10, Vol.517, p.24-34

2021

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Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape

Molecular cancer research, 2022-01, Vol.20 (1), p.150-160

2022

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Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer

Cancer immunology research, 2023-05, Vol.11 (5), p.687-702

2023

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O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity

Laboratory investigation, 2019-02, Vol.99 (2), p.260-270

2019

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Hedgehog signaling interfaces with the Hexoseamine Biosynthetic Pathway to promote M2 polarization of mammary tumor associated macrophages

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.101-101.02

2021

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Hedgehog signaling induced metabolic reprogramming is essential for M2 polarization of macrophages in breast cancer

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.164-164.16

2020

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Abemaciclib in patients (pts) with esophageal cancer (EC) with CDKN2A loss or mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Journal of clinical oncology, 2024-01, Vol.42 (3_suppl), p.308-308

2024

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Quantitative longitudinal imaging reveals that inhibiting Hedgehog activity alleviates the hypoxic tumor landscape: Longitudinal hypoxia imaging is a strategy to monitor the efficacy of Hh inhibition

Molecular cancer research, 2021-09, Vol.20 (1), p.150-160

2021

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Talazoparib (Tala) in patients (pts) with colorectal cancer (CRC) with BRCA1/2 mutations (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Journal of clinical oncology, 2024-01, Vol.42 (3_suppl), p.106-106

2024

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Nivolumab plus ipilimumab (N+I) in patients (pts) with ovarian cancer (OC) with BRCA1/2 mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.5548-5548

2023

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Talazoparib (Tala) in patients (pts) with solid tumors with BRCA1/2 mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.3115-3115

2023

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Hedgehog Signaling Rewires M2 Macrophage and Regulatory T Cell Metabolism Within the Tumor Microenvironment of Breast Cancer

Hinshaw, Dominique C

2022

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ProQuest

Abstract 2367: Hedgehog signaling influences tumor immunogenicity by the modulation of T cell populations in breast cancer

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2367-2367

2023

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O-GlcNAcylation of GLI Transcription Factors in Hyperglycemic Conditions Augments Hedgehog activity: Hyperglycemic conditions upregulate GLI activity

Laboratory investigation, 2018-11, Vol.99 (2), p.260-270

2018

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Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8 + T cells in a mouse model of mammary carcinoma

Laboratory investigation, 2022-11, Vol.102 (11), p.1236

2022

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Regorafenib in Patients With Solid Tumors With BRAF Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study

JCO precision oncology, 2024-04, Vol.8, p.e2300527

2024

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Pertuzumab Plus Trastuzumab in Patients With Biliary Tract Cancer With ERBB2/3 Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study

Journal of clinical oncology, 2024-05, p.JCO2302078-JCO2302078

2024

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The Tumor Microenvironment Innately Modulates Cancer Progression

Merlin deficiency alters the redox management program in breast cancer

Ribosome biosynthesis and Hedgehog activity are cooperative actionable signaling mechanisms in breast cancer following radiotherapy

Hedgehog Signaling Regulates Metabolism and Polarization of Mammary Tumor-Associated Macrophages

A Metabolic Axis of Immune Intractability

Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma

Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study

Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding

Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape

Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer

O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity

Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study

Hedgehog signaling interfaces with the Hexoseamine Biosynthetic Pathway to promote M2 polarization of mammary tumor associated macrophages

Hedgehog signaling induced metabolic reprogramming is essential for M2 polarization of macrophages in breast cancer

Abemaciclib in patients (pts) with esophageal cancer (EC) with CDKN2A loss or mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Quantitative longitudinal imaging reveals that inhibiting Hedgehog activity alleviates the hypoxic tumor landscape: Longitudinal hypoxia imaging is a strategy to monitor the efficacy of Hh inhibition

Talazoparib (Tala) in patients (pts) with colorectal cancer (CRC) with BRCA1/2 mutations (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Nivolumab plus ipilimumab (N+I) in patients (pts) with ovarian cancer (OC) with BRCA1/2 mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Talazoparib (Tala) in patients (pts) with solid tumors with BRCA1/2 mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study

Hedgehog Signaling Rewires M2 Macrophage and Regulatory T Cell Metabolism Within the Tumor Microenvironment of Breast Cancer

Abstract 2367: Hedgehog signaling influences tumor immunogenicity by the modulation of T cell populations in breast cancer

O-GlcNAcylation of GLI Transcription Factors in Hyperglycemic Conditions Augments Hedgehog activity: Hyperglycemic conditions upregulate GLI activity

Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8 + T cells in a mouse model of mammary carcinoma

Regorafenib in Patients With Solid Tumors With BRAF Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study

Pertuzumab Plus Trastuzumab in Patients With Biliary Tract Cancer With ERBB2/3 Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study

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