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Can non-renal clearance and/or bioavailability of drugs be assessed reliably in renal impairment studies with oral drug administration?

International journal of clinical pharmacology and therapeutics, 2024-03

2024

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The Pharmacokinetics of Potassium in Humans Is Unusual

Journal of clinical pharmacology, 2016-10, Vol.56 (10), p.1212-1220

Hinderling, Peter H.

2016

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The pH dependency of the binding of drugs to plasma proteins in man

Therapeutic drug monitoring, 2005-02, Vol.27 (1), p.71-85

2005

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Why Collecting Pharmacokinetic Information After Intravenous Drug Administration Is Important

Clinical pharmacology in drug development, 2020-02, Vol.9 (2), p.146-150

2020

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Quantitative Assessment of the Effect of Chronic Kidney Disease on the Nonrenal Clearance of 10 Drugs After Intravenous Administration

Clinical pharmacology in drug development, 2019-02, Vol.8 (2), p.138-151

2019

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Evaluation of a novel method to estimate absolute bioavailability of drugs from oral data

Biopharmaceutics & drug disposition, 2003-01, Vol.24 (1), p.1-16

Hinderling, Peter H.

2003

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Systemic Availability of the Active Metabolite Hydroxy-Fasudil After Administration of Fasudil to Different Sites of the Human Gastrointestinal Tract

Journal of clinical pharmacology, 2007-01, Vol.47 (1), p.19-25

2007

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Red blood cells: a neglected compartment in pharmacokinetics and pharmacodynamics

Pharmacological reviews, 1997-09, Vol.49 (3), p.279

Hinderling, P H

1997

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The Pharmacokinetics and Pharmacodynamics of Fludarabine Phosphate in Patients with Renal Impairment: A Prospective Dose Adjustment Study

Cancer investigation, 2002, Vol.20 (7-8), p.904-913

2002

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Biased estimates of nonrenal clearance

Journal of pharmaceutical sciences, 2001-07, Vol.90 (7), p.960-966

Hinderling, Peter H.

2001

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Pharmacokinetics and pharmacodynamics of sotalol in a pediatric population with supraventricular and ventricular tachyarrhythmia

Clinical pharmacology and therapeutics, 2001-03, Vol.69 (3), p.145-157

2001

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Importance of using controls in in vivo experiments

Radiology, 2004-10, Vol.233 (1), p.297-299

2004

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Population pharmacokinetics and pharmacodynamics of sotalol in pediatric patients with supraventricular or ventricular tachyarrhythmia

Journal of pharmacokinetics and pharmacodynamics, 2001-12, Vol.28 (6), p.555-575

2001

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Single-Dose Pharmacokinetics of Sotalol in a Pediatric Population with Supraventricular and/or Ventricular Tachyarrhythmia

Journal of clinical pharmacology, 2001-01, Vol.41 (1), p.35-43

2001

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Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans

Therapeutic drug monitoring, 1991-09, Vol.13 (5), p.381-401

1991

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Inhibition of thrombin by Iopromide in vitro

Therapeutic drug monitoring, 2001-04, Vol.23 (2), p.93-99

2001

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Pharmacokinetic, pharmacodynamic, and safety evaluation of an accelerated dose titration regimen of sotalol in healthy middle-aged subjects

Clinical pharmacology and therapeutics, 1999-07, Vol.66 (1), p.91-99

1999

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Comparative In Vivo Evaluation of a Radioimmunoassay and a Chromatographic Assay for the Measurement of Digoxin in Biological Fluids

Journal of pharmaceutical sciences, 1986-05, Vol.75 (5), p.517-521

1986

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Commentary 'Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: A critical review ' (I. Mahmood)

Biopharmaceutics & drug disposition, 1997-12, Vol.18 (9), p.821-824

Hinderling, Peter H.

1997

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Absolute Bioavailability Estimated from Oral Data

Journal of pharmaceutical sciences, 1995-03, Vol.84 (3), p.385-386

1995

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Single-Dose Pharmacokinetics of Sotalol in a Pediatric Population with Supraventricular and/or Ventricular Tachyarrhythmia

Journal of clinical pharmacology, 2001-01, Vol.41 (1), p.35-43

2001

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Kinetics and dynamics of sematilide

Therapeutic drug monitoring, 1995-10, Vol.17 (5), p.437-444

1995

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Pharmacokinetics of Sematilide in Renal Failure

Journal of clinical pharmacology, 1996-02, Vol.36 (2), p.131-143

1996

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Comparative serum estradiol profiles from a new once-a-week transdermal estradiol patch and a twice-a-week transdermal estradiol patch

Therapeutic drug monitoring, 1997-02, Vol.19 (1), p.37-42

1997

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Kinetics of Partitioning and Binding of Digoxin and Its Analogues in the Subcompartments of Blood

Journal of pharmaceutical sciences, 1984-08, Vol.73 (8), p.1042-1053

Hinderling, Peter H.

1984

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Can non-renal clearance and/or bioavailability of drugs be assessed reliably in renal impairment studies with oral drug administration?

The Pharmacokinetics of Potassium in Humans Is Unusual

The pH dependency of the binding of drugs to plasma proteins in man

Why Collecting Pharmacokinetic Information After Intravenous Drug Administration Is Important

Quantitative Assessment of the Effect of Chronic Kidney Disease on the Nonrenal Clearance of 10 Drugs After Intravenous Administration

Evaluation of a novel method to estimate absolute bioavailability of drugs from oral data

Systemic Availability of the Active Metabolite Hydroxy-Fasudil After Administration of Fasudil to Different Sites of the Human Gastrointestinal Tract

Red blood cells: a neglected compartment in pharmacokinetics and pharmacodynamics

The Pharmacokinetics and Pharmacodynamics of Fludarabine Phosphate in Patients with Renal Impairment: A Prospective Dose Adjustment Study

Biased estimates of nonrenal clearance

Pharmacokinetics and pharmacodynamics of sotalol in a pediatric population with supraventricular and ventricular tachyarrhythmia

Importance of using controls in in vivo experiments

Population pharmacokinetics and pharmacodynamics of sotalol in pediatric patients with supraventricular or ventricular tachyarrhythmia

Single-Dose Pharmacokinetics of Sotalol in a Pediatric Population with Supraventricular and/or Ventricular Tachyarrhythmia

Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans

Inhibition of thrombin by Iopromide in vitro

Pharmacokinetic, pharmacodynamic, and safety evaluation of an accelerated dose titration regimen of sotalol in healthy middle-aged subjects

Comparative In Vivo Evaluation of a Radioimmunoassay and a Chromatographic Assay for the Measurement of Digoxin in Biological Fluids

Commentary 'Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: A critical review ' (I. Mahmood)

Absolute Bioavailability Estimated from Oral Data

Single-Dose Pharmacokinetics of Sotalol in a Pediatric Population with Supraventricular and/or Ventricular Tachyarrhythmia

Kinetics and dynamics of sematilide

Pharmacokinetics of Sematilide in Renal Failure

Comparative serum estradiol profiles from a new once-a-week transdermal estradiol patch and a twice-a-week transdermal estradiol patch

Kinetics of Partitioning and Binding of Digoxin and Its Analogues in the Subcompartments of Blood

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