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Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

Journal of molecular biology, 2009-01, Vol.385 (3), p.693-713

2009

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Drug-induced functional cardiotoxicity screening in stem cell-derived human and mouse cardiomyocytes: Effects of reference compounds

Journal of pharmacological and toxicological methods, 2013-07, Vol.68 (1), p.97-111

Himmel, Herbert M.

2013

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Non-Nucleoside Reverse Transcriptase Inhibitors Join Forces with Integrase Inhibitors to Combat HIV

Pharmaceuticals (Basel, Switzerland), 2020-06, Vol.13 (6), p.122

2020

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Irreversible transformations of native celluloses, upon exposure to elevated temperatures

Carbohydrate polymers, 2014-01, Vol.100 (1), p.2-8

2014

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Deposition of Lignin Droplets Produced During Dilute Acid Pretreatment of Maize Stems Retards Enzymatic Hydrolysis of Cellulose

Biotechnology progress, 2007, Vol.23 (6), p.1333-1339

2007

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Safety pharmacology assessment of central nervous system function in juvenile and adult rats: Effects of pharmacological reference compounds

Journal of pharmacological and toxicological methods, 2008-09, Vol.58 (2), p.129-146

Himmel, Herbert M.

2008

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Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7582-7591

2005

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The On–Off Switch in Regulated Myosins: Different Triggers but Related Mechanisms

Journal of molecular biology, 2009-12, Vol.394 (3), p.496-505

2009

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Crystallographic Findings on the Internally Uncoupled and Near-Rigor States of Myosin: Further Insights into the Mechanics of the Motor

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.12645-12650

2002

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Identification of Alternative Binding Sites for Inhibitors of HIV-1 Ribonuclease H Through Comparative Analysis of Virtual Enrichment Studies

Journal of chemical information and modeling, 2011-08, Vol.51 (8), p.1986-1998

2011

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Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106571-106571, Article 106571

2019

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Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential

Journal of pharmacological and toxicological methods, 2007-09, Vol.56 (2), p.145-158

Himmel, Herbert M.

2007

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Enzymes, energy, and the environment: a strategic perspective on the U.S. Department of Energy's Research and Development Activities for Bioethanol

Biotechnology progress, 1999, Vol.15 (5), p.817-827

1999

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Cost Effectiveness of Neoadjuvant Chemotherapy in Locally Advanced Operable Head and Neck Cancer Followed by Surgery and Postoperative Radiotherapy: A Markov Model-Based Decision Analysis

Oncology, 2013-01, Vol.84 (6), p.336-341

2013

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Fungal Cellulases

Chemical reviews, 2015-02, Vol.115 (3), p.1308-1448

2015

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Myosin Subfragment 1 Structures Reveal a Partially Bound Nucleotide and a Complex Salt Bridge That Helps Couple Nucleotide and Actin Binding

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (24), p.8930-8935

2004

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Ab initio molecular dynamics simulations of β- d-glucose and β- d-xylose degradation mechanisms in acidic aqueous solution

Carbohydrate research, 2005-10, Vol.340 (14), p.2319-2327

2005

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How Does Plant Cell Wall Nanoscale Architecture Correlate with Enzymatic Digestibility?

Science (American Association for the Advancement of Science), 2012-11, Vol.338 (6110), p.1055-1060

2012

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Multiple synaptic and membrane sites of anesthetic action in the CA1 region of rat hippocampal slices

BMC neuroscience, 2004-12, Vol.5 (1), p.52-52

2004

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Subtype-specific statistical causalities in parkinsonian tremor

Neuroscience, 2012-05, Vol.210, p.353-362

2012

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Visualizing lignin coalescence and migration through maize cell walls following thermochemical pretreatment

Biotechnology and bioengineering, 2008-12, Vol.101 (5), p.913-925

2008

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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

Scientific reports, 2020-03, Vol.10 (1), p.5627, Article 5627

2020

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Pupillary function test in rat: Establishment of imaging setup and pharmacological validation within modified Irwin test

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106588-106588, Article 106588

2019

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Intracellular Calcium, Currents, and Stimulus-Response Coupling in Endothelial Cells

Hypertension (Dallas, Tex. 1979), 1993-01, Vol.21 (1), p.112-127

1993

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Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition

Drug-induced functional cardiotoxicity screening in stem cell-derived human and mouse cardiomyocytes: Effects of reference compounds

Non-Nucleoside Reverse Transcriptase Inhibitors Join Forces with Integrase Inhibitors to Combat HIV

Irreversible transformations of native celluloses, upon exposure to elevated temperatures

Deposition of Lignin Droplets Produced During Dilute Acid Pretreatment of Maize Stems Retards Enzymatic Hydrolysis of Cellulose

Safety pharmacology assessment of central nervous system function in juvenile and adult rats: Effects of pharmacological reference compounds

Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains

The On–Off Switch in Regulated Myosins: Different Triggers but Related Mechanisms

Crystallographic Findings on the Internally Uncoupled and Near-Rigor States of Myosin: Further Insights into the Mechanics of the Motor

Identification of Alternative Binding Sites for Inhibitors of HIV-1 Ribonuclease H Through Comparative Analysis of Virtual Enrichment Studies

Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison

Suitability of commonly used excipients for electrophysiological in-vitro safety pharmacology assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential

Enzymes, energy, and the environment: a strategic perspective on the U.S. Department of Energy's Research and Development Activities for Bioethanol

Cost Effectiveness of Neoadjuvant Chemotherapy in Locally Advanced Operable Head and Neck Cancer Followed by Surgery and Postoperative Radiotherapy: A Markov Model-Based Decision Analysis

Fungal Cellulases

Myosin Subfragment 1 Structures Reveal a Partially Bound Nucleotide and a Complex Salt Bridge That Helps Couple Nucleotide and Actin Binding

Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective

Ab initio molecular dynamics simulations of β- d-glucose and β- d-xylose degradation mechanisms in acidic aqueous solution

How Does Plant Cell Wall Nanoscale Architecture Correlate with Enzymatic Digestibility?

Multiple synaptic and membrane sites of anesthetic action in the CA1 region of rat hippocampal slices

Subtype-specific statistical causalities in parkinsonian tremor

Visualizing lignin coalescence and migration through maize cell walls following thermochemical pretreatment

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

Pupillary function test in rat: Establishment of imaging setup and pharmacological validation within modified Irwin test

Intracellular Calcium, Currents, and Stimulus-Response Coupling in Endothelial Cells

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