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Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

The EMBO journal, 2016-04, Vol.35 (8), p.831-844

2016

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Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly

Developmental cell, 2012-02, Vol.22 (2), p.459-467

2012

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Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

Cell, 2012-05, Vol.149 (5), p.1008-1022

2012

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The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression

Cell reports (Cambridge), 2017-08, Vol.20 (6), p.1396-1408

2017

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Mapping the Shh long-range regulatory domain

Development (Cambridge), 2014-10, Vol.141 (20), p.3934-3943

2014

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Development of five digits is controlled by a bipartite long-range cis-regulator

Development (Cambridge), 2014-04, Vol.141 (8), p.1715-1725

2014

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UBR5 promotes antiviral immunity by disengaging the transcriptional brake on RIG-I like receptors

Nature communications, 2024-01, Vol.15 (1), p.780-780, Article 780

2024

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Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

Nature genetics, 2010-01, Vol.42 (1), p.89-93

2010

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Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly

Human molecular genetics, 2008-04, Vol.17 (7), p.978-985

2008

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Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis

PLoS genetics, 2021-04, Vol.17 (4), p.e1009275

2021

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Enhancers: From Developmental Genetics to the Genetics of Common Human Disease

Developmental cell, 2011-07, Vol.21 (1), p.17-19

2011

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Anterior-posterior differences in HoxD chromatin topology in limb development

Development (Cambridge), 2012-09, Vol.139 (17), p.3157-3167

2012

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Enhancer-adoption as a mechanism of human developmental disease

Human mutation, 2011-12, Vol.32 (12), p.1492-1499

2011

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Lineage tracing in the adult mouse corneal epithelium supports the limbal epithelial stem cell hypothesis with intermittent periods of stem cell quiescence

Stem cell research, 2015-11, Vol.15 (3), p.665-677

2015

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Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites

PloS one, 2014-10, Vol.9 (10), p.e109193-e109193

2014

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Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia

PloS one, 2013-08, Vol.8 (8), p.e71117-e71117

2013

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Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors

eLife, 2017-09, Vol.6

2017

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Developmentally regulated Shh expression is robust to TAD perturbations

Development (Cambridge), 2019-09, Vol.146 (19)

2019

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Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas

PloS one, 2011-06, Vol.6 (6), p.e21753-e21753

2011

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Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity

Development (Cambridge), 2016-08, Vol.143 (16), p.2994-3001

2016

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Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasis

PloS one, 2011-12, Vol.6 (12), p.e28895-e28895

2011

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Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice

Stem cell research, 2018-07, Vol.30, p.1-11

2018

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Cohesin is required for long-range enhancer action at the Shh locus

Nature structural & molecular biology, 2022-09, Vol.29 (9), p.891-897

2022

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A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium

BMC research notes, 2018-10, Vol.11 (1), p.705-705, Article 705

2018

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Left-right asymmetry in gut development: what happens next

BioEssays, 2009-10, Vol.31 (10), p.1026-1037

2009

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Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response

Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly

Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development

The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression

Mapping the Shh long-range regulatory domain

Development of five digits is controlled by a bipartite long-range cis-regulator

UBR5 promotes antiviral immunity by disengaging the transcriptional brake on RIG-I like receptors

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly

Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis

Enhancers: From Developmental Genetics to the Genetics of Common Human Disease

Anterior-posterior differences in HoxD chromatin topology in limb development

Enhancer-adoption as a mechanism of human developmental disease

Lineage tracing in the adult mouse corneal epithelium supports the limbal epithelial stem cell hypothesis with intermittent periods of stem cell quiescence

Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites

Increased corneal epithelial turnover contributes to abnormal homeostasis in the Pax6(+/-) mouse model of aniridia

Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors

Developmentally regulated Shh expression is robust to TAD perturbations

Impaired spleen formation perturbs morphogenesis of the gastric lobe of the pancreas

Shh and ZRS enhancer colocalisation is specific to the zone of polarising activity

Effects of aberrant Pax6 gene dosage on mouse corneal pathophysiology and corneal epithelial homeostasis

Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice

Cohesin is required for long-range enhancer action at the Shh locus

A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium

Left-right asymmetry in gut development: what happens next

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