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IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation

Nature communications, 2016-11, Vol.7 (1), p.13567-15, Article 13567

2016

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Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

Molecular cancer, 2010-06, Vol.9 (1), p.154-154, Article 154

2010

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Circulating Galectin-3 Promotes Metastasis by Modifying MUC1 Localization on Cancer Cell Surface

Cancer research (Chicago, Ill.), 2009-09, Vol.69 (17), p.6799-6806

2009

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Chromatin landscapes of retroviral and transposon integration profiles

PLoS genetics, 2014-04, Vol.10 (4), p.e1004250

2014

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Galectin-3 Interaction with Thomsen-Friedenreich Disaccharide on Cancer-associated MUC1 Causes Increased Cancer Cell Endothelial Adhesion

The Journal of biological chemistry, 2007-01, Vol.282 (1), p.773-781

2007

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Insulin receptor substrate 4 (IRS4) is a constitutive active oncogenic driver collaborating with HER2 and causing therapeutic resistance

Molecular & cellular oncology, 2017-03, Vol.4 (2), p.e1279722-e1279722

2017

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MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA

PloS one, 2016-10, Vol.11 (10), p.e0165031-e0165031

2016

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Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors

PloS one, 2013-05, Vol.8 (5), p.e62113

2013

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A STAT-responsive Element in the Promoter of the Episialin/MUC1 Gene Is Involved in Its Overexpression in Carcinoma Cells

The Journal of biological chemistry, 2001-03, Vol.276 (9), p.6191-6199

2001

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Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas

Oncogene, 2004-08, Vol.23 (36), p.6047-6055

2004

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Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells

Cell death and differentiation, 2017-11, Vol.24 (11), p.1937-1947

2017

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MUC1/episialin: a critical barrier in the female reproductive tract

Journal of reproductive immunology, 1999-12, Vol.45 (2), p.127-158

1999

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RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis

Gut, 2017-06, Vol.66 (6), p.1095

2017

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MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer

Nature genetics, 2007-06, Vol.39 (6), p.759-769

2007

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R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling

Cancer letters, 2023-08, Vol.568, p.216301-216301, Article 216301

2023

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R‐spondin‐3 is an oncogenic driver of poorly differentiated invasive breast cancer

The Journal of pathology, 2022-11, Vol.258 (3), p.289-299

2022

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Recent translational research: oncogene discovery by insertional mutagenesis gets a new boost

Breast cancer research : BCR, 2006-01, Vol.8 (1), p.102-102, Article 102

Hilkens, John

2006

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Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance

Oncogene, 2018-03, Vol.37 (12), p.1594-1609

2018

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Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing

Life science alliance, 2024-06, Vol.7 (6), p.e202302366

2024

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A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1

Molecular biology of the cell, 1996-04, Vol.7 (4), p.565-577

1996

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Chromatin Landscapes of Retroviral and Transposon Integration Profiles: e1004250

PLoS genetics, 2014-04, Vol.10 (4)

2014

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Episialin (MUC1) Overexpression Inhibits Integrin-Mediated Cell Adhesion to Extracellular Matrix Components

The Journal of cell biology, 1995-04, Vol.129 (1), p.255-265

1995

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Immunohistochemical study of mucin carbohydrates and core proteins in hepatolithiasis and cholangiocarcinoma

International journal of cancer, 1993-08, Vol.55 (1), p.82-91

1993

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AsialoGM1 and integrin α2β1 mediate prostate cancer progression

International journal of oncology, 2009-10, Vol.35 (4), p.693-699

2009

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Altered expression and allelic association of the hypervariable membrane mucin MUC1 in Helicobacter pylori gastritis

Gastroenterology (New York, N.Y. 1943), 2002-07, Vol.123 (1), p.41-49

2002

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IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation

Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

Circulating Galectin-3 Promotes Metastasis by Modifying MUC1 Localization on Cancer Cell Surface

Chromatin landscapes of retroviral and transposon integration profiles

Galectin-3 Interaction with Thomsen-Friedenreich Disaccharide on Cancer-associated MUC1 Causes Increased Cancer Cell Endothelial Adhesion

Insulin receptor substrate 4 (IRS4) is a constitutive active oncogenic driver collaborating with HER2 and causing therapeutic resistance

MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors

A STAT-responsive Element in the Promoter of the Episialin/MUC1 Gene Is Involved in Its Overexpression in Carcinoma Cells

Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas

Interaction of galectin-3 with MUC1 on cell surface promotes EGFR dimerization and activation in human epithelial cancer cells

MUC1/episialin: a critical barrier in the female reproductive tract

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer

R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling

R‐spondin‐3 is an oncogenic driver of poorly differentiated invasive breast cancer

Recent translational research: oncogene discovery by insertional mutagenesis gets a new boost

Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance

Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing

A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1

Chromatin Landscapes of Retroviral and Transposon Integration Profiles: e1004250

Episialin (MUC1) Overexpression Inhibits Integrin-Mediated Cell Adhesion to Extracellular Matrix Components

Immunohistochemical study of mucin carbohydrates and core proteins in hepatolithiasis and cholangiocarcinoma

AsialoGM1 and integrin α2β1 mediate prostate cancer progression

Altered expression and allelic association of the hypervariable membrane mucin MUC1 in Helicobacter pylori gastritis

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