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Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

British journal of cancer, 2014-03, Vol.110 (5), p.1155-1162

2014

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Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

Annals of oncology, 2006-05, Vol.17 (5), p.866-873

2006

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Combination of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma: Results from a phase I extension trial

European journal of cancer (1990), 2009-03, Vol.45 (4), p.579-587

2009

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P1262: EZH2 INHIBITORS MEDIATE PLATINUM RESISTANCE BY ENHANCED EFFLUX

HemaSphere, 2022-06, Vol.6 (Suppl), p.1147-1148

2022

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Dose-escalated treosulphan in combination with cyclophosphamide as a new preparative regimen for allogeneic haematopoietic stem cell transplantation in patients with an increased risk for regimen-related complications

Bone marrow transplantation (Basingstoke), 2005-02, Vol.35 (3), p.233-241

2005

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The Ras-Raf-MEK-ERK pathway in the treatment of cancer

Onkologie, 2002-12, Vol.25 (6), p.511

2002

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Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin or cisplatin in patients with advanced non-small-cell lung cancer (NSCLC)

Annals of oncology, 2016-10, Vol.27 (10), p.1895-1902

2016

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Oxaliplatin-DNA adduct formation in white blood cells of cancer patients

British journal of cancer, 2008-06, Vol.98 (12), p.1959-1965

2008

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Results of phase I pharmacokinetic and pharmacodynamic studies of the Raf kinase inhibitor BAY 43-9006 in patients with solid tumors

International journal of clinical pharmacology and therapeutics, 2002-12, Vol.40 (12), p.580

2002

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Phase II study of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer

Investigational new drugs, 2012-06, Vol.30 (3), p.1138-1143

2012

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Novel antitumoral compound isolated from Clusia rosea

International journal of clinical pharmacology and therapeutics, 2003-12, Vol.41 (12), p.622

2003

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A phase I clinical and pharmacokinetic study of the Raf kinase inhibitor (RKI) BAY 43-9006 administered in combination with doxorubicin in patients with solid tumors

International journal of clinical pharmacology and therapeutics, 2003-12, Vol.41 (12), p.620

2003

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Safety, tolerability and pharmacokinetic properties of the novel triazene TriN 2755 in tumour bearing dogs – a phase I study

Veterinary & comparative oncology, 2017-03, Vol.15 (1), p.94-104

2017

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Antitumor effect and potentiation or reduction in cytotoxic drug activity in human colon carcinoma cells by the Raf kinase inhibitor (RKI) BAY 43-9006

International journal of clinical pharmacology and therapeutics, 2003-12, Vol.41 (12), p.616

2003

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Defining the role of MRP-mediated efflux and glutathione in detoxification of oxaliplatin

Pharmazie, 2013-07, Vol.68 (7), p.622-627

2013

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Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

British journal of cancer, 1999-12, Vol.81 (8), p.1304-1310

1999

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Femoral head necrosis in three patients with relapsed ovarian cancer receiving high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation

Bone marrow transplantation (Basingstoke), 2003-03, Vol.31 (6), p.487-491

2003

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ERK1/2 phosphorylation: a biomarker analysis within a phase I study with the new Raf kinase inhibitor BAY43-9006

International journal of clinical pharmacology and therapeutics, 2002-12, Vol.40 (12), p.567

2002

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Clinical pharmacokinetics of intravenous treosulfan in patients with advanced solid tumors

Cancer chemotherapy and pharmacology, 1998, Vol.42 (2), p.99-104

1998

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The influence of liver metastases on the pharmacokinetics of doxorubicin---a population-based pharmacokinetic project of the CESAR-APOH

International journal of clinical pharmacology and therapeutics, 2003-12, Vol.41 (12), p.598

2003

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Safety, efficacy and pharmacokinetics of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer

International journal of clinical pharmacology and therapeutics, 2010-07, Vol.48 (7), p.473

2010

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Circadian rhythm in the regulation of the MAP kinase pathway--pitfall in the determination of surrogate parameters?

International journal of clinical pharmacology and therapeutics, 2003-12, Vol.41 (12), p.614

2003

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Results of a phase I trial of BAY 43-9006 in combination with doxorubicin in patients with primary hepatic cancer

International journal of clinical pharmacology and therapeutics, 2004-11, Vol.42 (11), p.650

2004

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Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

Cancer chemotherapy and pharmacology, 2000, Vol.45 (6), p.483-488

2000

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Chemosensitivity of conjunctival melanoma cell lines to chemotherapeutic agents

International journal of clinical pharmacology and therapeutics, 2011-01, Vol.49 (1), p.78

2011

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Phase I study of panobinostat and imatinib in patients with treatment-refractory metastatic gastrointestinal stromal tumors

Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

Combination of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma: Results from a phase I extension trial

P1262: EZH2 INHIBITORS MEDIATE PLATINUM RESISTANCE BY ENHANCED EFFLUX

Dose-escalated treosulphan in combination with cyclophosphamide as a new preparative regimen for allogeneic haematopoietic stem cell transplantation in patients with an increased risk for regimen-related complications

The Ras-Raf-MEK-ERK pathway in the treatment of cancer

Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin or cisplatin in patients with advanced non-small-cell lung cancer (NSCLC)

Oxaliplatin-DNA adduct formation in white blood cells of cancer patients

Results of phase I pharmacokinetic and pharmacodynamic studies of the Raf kinase inhibitor BAY 43-9006 in patients with solid tumors

Phase II study of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer

Novel antitumoral compound isolated from Clusia rosea

A phase I clinical and pharmacokinetic study of the Raf kinase inhibitor (RKI) BAY 43-9006 administered in combination with doxorubicin in patients with solid tumors

Safety, tolerability and pharmacokinetic properties of the novel triazene TriN 2755 in tumour bearing dogs – a phase I study

Antitumor effect and potentiation or reduction in cytotoxic drug activity in human colon carcinoma cells by the Raf kinase inhibitor (RKI) BAY 43-9006

Defining the role of MRP-mediated efflux and glutathione in detoxification of oxaliplatin

Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

Femoral head necrosis in three patients with relapsed ovarian cancer receiving high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation

ERK1/2 phosphorylation: a biomarker analysis within a phase I study with the new Raf kinase inhibitor BAY43-9006

Clinical pharmacokinetics of intravenous treosulfan in patients with advanced solid tumors

The influence of liver metastases on the pharmacokinetics of doxorubicin---a population-based pharmacokinetic project of the CESAR-APOH

Safety, efficacy and pharmacokinetics of nimotuzumab, a humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody, in patients with locally advanced or metastatic pancreatic cancer

Circadian rhythm in the regulation of the MAP kinase pathway--pitfall in the determination of surrogate parameters?

Results of a phase I trial of BAY 43-9006 in combination with doxorubicin in patients with primary hepatic cancer

Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

Chemosensitivity of conjunctival melanoma cell lines to chemotherapeutic agents

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