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Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissue

Gene therapy, 2013-04, Vol.20 (4), p.417-424

2013

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High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

Gene therapy, 2010-04, Vol.17 (4), p.503-510

2010

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AAV-mediated gene transfer for the treatment of hemophilia B: problems and prospects

Gene therapy, 2008-06, Vol.15 (11), p.870-875

2008

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Gene therapy for haemophilia: a long and winding road

Journal of thrombosis and haemostasis, 2011-07, Vol.9, p.2-11

HIGH, K. A.

2011

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Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector

Nature genetics, 2000-03, Vol.24 (3), p.257-261

2000

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A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

Journal of thrombosis and haemostasis, 2008-02, Vol.6 (2), p.339-345

2008

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Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

Nature genetics, 1995-05, Vol.10 (1), p.119-121

1995

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Progress in the molecular biology of inherited bleeding disorders

Haemophilia : the official journal of the World Federation of Hemophilia, 2008-07, Vol.14 (s3), p.130-137

2008

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Prevalence of the factor V Leiden mutation in children and neonates with thromboembolic disease

The Journal of pediatrics, 1998-12, Vol.133 (6), p.777-781

1998

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Gene Transfer as an Approach to Treating Hemophilia

Circulation research, 2001-02, Vol.88 (2), p.137-144

High, Katherine A

2001

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Gene therapy in haemophilia - going for cure?

Haemophilia : the official journal of the World Federation of Hemophilia, 2010-05, Vol.16 (s3), p.24-28

2010

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Enhanced γ-Carboxylation of Recombinant Factor X Using a Chimeric Construct Containing the Prothrombin Propeptide

Biochemistry (Easton), 2000-11, Vol.39 (46), p.14322-14329

2000

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Intravenous administration of an E1/E3-deleted adenoviral vector induces tolerance to factor IX in C57BL/6 mice

Gene therapy, 2001-03, Vol.8 (5), p.354-361

2001

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Canine Hemophilia B Resulting from a Point Mutation with Unusual Consequences

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (24), p.10095-10099

1989

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Progress and Prospects: Gene Therapy Clinical Trials (Part 2)

Gene therapy, 2007-11, Vol.14 (22), p.1555-1563

2007

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AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B

Blood, 2003-04, Vol.101 (8), p.2963-2972

2003

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Successful Expression of Human Factor IX Following Repeat Administration of an Adenoviral Vector in Mice

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (7), p.3056-3061

1996

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A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism

The Journal of clinical investigation, 1996-10, Vol.98 (7), p.1619-1625

1996

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Special lectures in haemophilia management

Haemophilia : the official journal of the World Federation of Hemophilia, 2010-07, Vol.16 (s5), p.22-28

2010

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Gene therapy: a 2001 perspective

Haemophilia : the official journal of the World Federation of Hemophilia, 2001-01, Vol.7 (s1), p.23-27

High, K.A.

2001

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Generation of a novel factor IX with augmented clotting activities in vitro and in vivo

Journal of thrombosis and haemostasis, 2010-08, Vol.8 (8), p.1773-1783

2010

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Protein Replacement Therapy and Gene Transfer in Canine Models of Hemophilia A, Hemophilia B, von Willebrand Disease, and Factor VII Deficiency

ILAR journal, 2009, Vol.50 (2), p.144-167

2009

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Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector

Nature medicine, 1999-01, Vol.5 (1), p.56-63

1999

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A novel missense mutation responsible for factor VII deficiency in research Beagle colonies

Journal of thrombosis and haemostasis, 2006-12, Vol.4 (12), p.2616-2622

2006

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Gene therapy in haematology and oncology

The Lancet (British edition), 2000-12, Vol.356, p.S8-S8

High, Katherine A

2000

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Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissue

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

AAV-mediated gene transfer for the treatment of hemophilia B: problems and prospects

Gene therapy for haemophilia: a long and winding road

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector

A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A

Progress in the molecular biology of inherited bleeding disorders

Prevalence of the factor V Leiden mutation in children and neonates with thromboembolic disease

Gene Transfer as an Approach to Treating Hemophilia

Gene therapy in haemophilia - going for cure?

Enhanced γ-Carboxylation of Recombinant Factor X Using a Chimeric Construct Containing the Prothrombin Propeptide

Intravenous administration of an E1/E3-deleted adenoviral vector induces tolerance to factor IX in C57BL/6 mice

Canine Hemophilia B Resulting from a Point Mutation with Unusual Consequences

Progress and Prospects: Gene Therapy Clinical Trials (Part 2)

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B

Successful Expression of Human Factor IX Following Repeat Administration of an Adenoviral Vector in Mice

A mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism

Special lectures in haemophilia management

Gene therapy: a 2001 perspective

Generation of a novel factor IX with augmented clotting activities in vitro and in vivo

Protein Replacement Therapy and Gene Transfer in Canine Models of Hemophilia A, Hemophilia B, von Willebrand Disease, and Factor VII Deficiency

Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector

A novel missense mutation responsible for factor VII deficiency in research Beagle colonies

Gene therapy in haematology and oncology

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