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From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists

Trends in pharmacological sciences (Regular ed.), 2013-10, Vol.34 (10), p.560-570

2013

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Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test

Psychopharmacologia, 2007-12, Vol.195 (2), p.223-234

2007

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Low Doses of Psilocybin and Ketamine Enhance Motivation and Attention in Poor Performing Rats: Evidence for an Antidepressant Property

Frontiers in pharmacology, 2021-02, Vol.12, p.640241

2021

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The 5-HT2C Receptor Agonist Lorcaserin Reduces Nicotine Self-Administration, Discrimination, and Reinstatement: Relationship to Feeding Behavior and Impulse Control

Neuropsychopharmacology (New York, N.Y.), 2012-04, Vol.37 (5), p.1177-1191

2012

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Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice

Neuropsychopharmacology (New York, N.Y.), 2017-10, Vol.42 (11), p.2178-2187

2017

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Impulsive action in the 5-choice serial reaction time test in 5-HT2C receptor null mutant mice

Psychopharmacology, 2013-04, Vol.226 (3), p.561-570

2013

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Characterization of Amphetamine, Methylphenidate, Nicotine, and Atomoxetine on Measures of Attention, Impulsive Action, and Motivation in the Rat: Implications for Translational Research

Frontiers in pharmacology, 2020-04, Vol.11, p.427-427

2020

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Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential

Pharmacology & therapeutics (Oxford), 2020-01, Vol.205, p.107417, Article 107417

2020

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The effects of the 5-HT2c receptor antagonist SB242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists

Psychopharmacologia, 2006-09, Vol.187 (4), p.515-525

2006

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Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew)

Frontiers in pharmacology, 2016-08, Vol.7, p.263-263

2016

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The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

Psychopharmacology, 2005-04, Vol.179 (1), p.207-217

2005

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Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent

Neuropharmacology, 2004-06, Vol.46 (7), p.907-917

2004

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Effect of a single psilocybin treatment on Fos protein expression in male rat brain

Neuroscience, 2024-02, Vol.539, p.1-11

2024

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Contrasting effects of d-amphetamine and atomoxetine on measures of impulsive action and choice

Pharmacology, biochemistry and behavior, 2021-08, Vol.207, p.173220, Article 173220

2021

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Therapeutic Potential of 5‑HT2C Receptor Agonists for Addictive Disorders

ACS chemical neuroscience, 2015-07, Vol.6 (7), p.1071-1088

2015

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Enhancing effects of nicotine and impairing effects of scopolamine on distinct aspects of performance in computerized attention and working memory tasks in marmoset monkeys

Neuropharmacology, 2006-08, Vol.51 (2), p.238-250

2006

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Effects of 5-HT2C receptor modulation and the NA reuptake inhibitor atomoxetine in tests of compulsive and impulsive behaviour

Neuropharmacology, 2020-06, Vol.170, p.108064, Article 108064

2020

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Effects of pimavanserin and lorcaserin on alcohol self-administration and reinstatement in male and female rats

Neuropharmacology, 2022-09, Vol.215, p.109150-109150, Article 109150

2022

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Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity

The Journal of neuroscience, 2002-08, Vol.22 (15), p.6713-6723

2002

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Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety

Pharmacology, biochemistry and behavior, 2002-04, Vol.71 (4), p.615-625

2002

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Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT2C receptor stimulation and 5-HT2A receptor blockade

Neuropharmacology, 2011-09, Vol.61 (3), p.468-477

2011

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Effects of 5-HT2C receptor stimulation in male mice on behaviour and Fos expression: Feeding, reward and impulsivity

Behavioural brain research, 2023-06, Vol.447, p.114438-114438, Article 114438

2023

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Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists

Journal of Psychopharmacology, 2017-11, Vol.31 (11), p.1403-1418

2017

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Enhanced attention and impulsive action following NMDA receptor GluN2B-selective antagonist pretreatment

Behavioural brain research, 2016-09, Vol.311, p.1-14

2016

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The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors

Behavioural brain research, 2007-12, Vol.185 (1), p.32-42

2007

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From obesity to substance abuse: therapeutic opportunities for 5-HT2C receptor agonists

Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test

Low Doses of Psilocybin and Ketamine Enhance Motivation and Attention in Poor Performing Rats: Evidence for an Antidepressant Property

The 5-HT2C Receptor Agonist Lorcaserin Reduces Nicotine Self-Administration, Discrimination, and Reinstatement: Relationship to Feeding Behavior and Impulse Control

Pharmacological Modulation of 5-HT2C Receptor Activity Produces Bidirectional Changes in Locomotor Activity, Responding for a Conditioned Reinforcer, and Mesolimbic DA Release in C57BL/6 Mice

Impulsive action in the 5-choice serial reaction time test in 5-HT2C receptor null mutant mice

Characterization of Amphetamine, Methylphenidate, Nicotine, and Atomoxetine on Measures of Attention, Impulsive Action, and Motivation in the Rat: Implications for Translational Research

Lorcaserin: A review of its preclinical and clinical pharmacology and therapeutic potential

The effects of the 5-HT2c receptor antagonist SB242084 on locomotor activity induced by selective, or mixed, indirect serotonergic and dopaminergic agonists

Profile of Antiemetic Activity of Netupitant Alone or in Combination with Palonosetron and Dexamethasone in Ferrets and Suncus murinus (House Musk Shrew)

The antinociceptive and anxiolytic-like effects of the metabotropic glutamate receptor 5 (mGluR5) antagonists, MPEP and MTEP, and the mGluR1 antagonist, LY456236, in rodents: a comparison of efficacy and side-effect profiles

Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent

Effect of a single psilocybin treatment on Fos protein expression in male rat brain

Contrasting effects of d-amphetamine and atomoxetine on measures of impulsive action and choice

Therapeutic Potential of 5‑HT2C Receptor Agonists for Addictive Disorders

Enhancing effects of nicotine and impairing effects of scopolamine on distinct aspects of performance in computerized attention and working memory tasks in marmoset monkeys

Effects of 5-HT2C receptor modulation and the NA reuptake inhibitor atomoxetine in tests of compulsive and impulsive behaviour

Effects of pimavanserin and lorcaserin on alcohol self-administration and reinstatement in male and female rats

Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity

Influence of the 5-HT2C receptor antagonist, SB-242084, in tests of anxiety

Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT2C receptor stimulation and 5-HT2A receptor blockade

Effects of 5-HT2C receptor stimulation in male mice on behaviour and Fos expression: Feeding, reward and impulsivity

Role of impulsivity and reward in the anti-obesity actions of 5-HT2C receptor agonists

Enhanced attention and impulsive action following NMDA receptor GluN2B-selective antagonist pretreatment

The effect of caffeine to increase reaction time in the rat during a test of attention is mediated through antagonism of adenosine A2A receptors

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