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Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

The Journal of pharmacology and experimental therapeutics, 2007-11, Vol.323 (2), p.469-475

2007

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Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

Journal of neuroinflammation, 2010-12, Vol.7 (1), p.95-95, Article 95

2010

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FTY720 sustains and restores neuronal function in the DA rat model of MOG-induced experimental autoimmune encephalomyelitis

Brain research bulletin, 2007-10, Vol.74 (5), p.307-316

2007

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Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-Cyanopyrimidines. Part 2

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (19), p.5280-5284

2008

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Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720

Progress in drug research, 2008, Vol.66, p.361, 363

2008

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Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity

European journal of immunology, 1987, Vol.17 (9), p.1359-1365

1987

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FK 506-Binding Protein Proline Rotamase is a Target for the Immunosuppressive Agent FK 506 in Saccharomyces cerevisiae

Proceedings of the National Academy of Sciences - PNAS, 1991-03, Vol.88 (5), p.1948-1952

1991

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Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo

Biochimica et biophysica acta. Molecular basis of disease, 1992-02, Vol.1138 (2), p.115-121

1992

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Prolactin as a Modulator of Lymphocyte Responsiveness Provides a Possible Mechanism of Action for Cyclosporine

Proceedings of the National Academy of Sciences - PNAS, 1986-04, Vol.83 (8), p.2599-2603

1986

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A novel secreted cyclophilin-like protein (SCYLP)

The Journal of biological chemistry, 1991-06, Vol.266 (17), p.10735-10738

1991

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SDZ PSC 833, A non‐immunosuppressive cyclosporine: Its potency in overcoming P‐glycoprotein‐mediated multidrug resistance of murine leukemia

International journal of cancer, 1992-02, Vol.50 (4), p.593-597

1992

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Pharmacologic interactions between the resistance‐modifying cyclosporine sdz psc 833 and etoposide (VP 16–213) enhance In Vivo cytostatic activity and toxicity

International journal of cancer, 1992-05, Vol.51 (3), p.433-438

1992

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Adenosine 3':5'-Monophosphate-dependent Protein Kinase and the Stimulation of Ovarian Nuclear Ribonucleic Acid Polymerase Activities

The Journal of biological chemistry, 1974-09, Vol.249 (17), p.5444-5451

1974

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A comparison of cyclosporine binding by cyclophilin and calmodulin and the identification of a novel 45 KD cyclosporine-binding phosphoprotein in Jurkat cells

Transplantation, 1988-08, Vol.46 (2 Suppl), p.35S-40S

1988

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Dispholidus typus (boomslang) snake venom: Purification and properties of the coagulant principle

Toxicon (Oxford), 1979, Vol.17 (5), p.489-498

1979

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Immunomodulating activities of ethylene-2,2'-bis(dithio)bis(ethanol) and related compounds. Effects on murine lymphocyte proliferation and functions in vitro

International journal of immunopharmacology, 1985, Vol.7 (1), p.129-140

1985

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MOLECULAR CHARACTERISTICS OF CYCLOPHILIN-CYCLOSPORINE INTERACTION

Transplantation, 1988-08, Vol.46 (Supplement), p.23-28S

1988

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Mechanism of action of gonadotropin. IV. Cyclic adenosine monophosphate-dependent translocation of ovarian cytoplasmic cyclic adenosine monophosphate-binding protein and protein kinase to nuclear acceptor sites

Endocrinology (Philadelphia), 1974-01, Vol.94 (1), p.168-183

1974

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Phosphorylation of myelin basic proteins: An age-dependent process affected by divalent cations and Co-Dergocrine (dihydroergotoxine)

Experimental aging research, 1983-01, Vol.9 (1), p.9-15

1983

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Mechanism of Action of Gonadotropin. IV. Cyclic Adenosine Monophosphate-Dependent Translocation of Ovarian Cytoplasmic Cyclic Adenosine Monophosphate-Binding Protein and Protein Kinase to Nuclear Acceptor Sites 1

Endocrinology (Philadelphia), 1974-01, Vol.94 (1), p.168-183

1974

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Mechanism of Action of Gonadotropin. III. Binding of Adenosine 3′,5′-Monophosphate by the 105,000 × g Supernatant Fraction from Homogenates of Calf Ovaries1

Endocrinology (Philadelphia), 1973-07, Vol.93 (1), p.217-230

1973

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Early head‐to‐pelvis computed tomography in out‐of‐hospital circulatory arrest without obvious etiology

Academic emergency medicine, 2021-04, Vol.28 (4), p.394-403

2021

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Studies on Adrenal Histones

The Journal of biological chemistry, 1970-09, Vol.245 (17), p.4321-4326

1970

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Emergency Department Discharge of Pulmonary Embolus Patients

Academic emergency medicine, 2018-09, Vol.25 (9), p.995-1003

2018

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The Use of Very Low Concentrations of High‐sensitivity Troponin T to Rule Out Acute Myocardial Infarction Using a Single Blood Test

Academic emergency medicine, 2016-09, Vol.23 (9), p.1004-1013

2016

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Brain penetration of the oral immunomodulatory drug FTY720 and its phosphorylation in the central nervous system during experimental autoimmune encephalomyelitis: consequences for mode of action in multiple sclerosis

Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

FTY720 sustains and restores neuronal function in the DA rat model of MOG-induced experimental autoimmune encephalomyelitis

Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-Cyanopyrimidines. Part 2

Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720

Cyclophilin binds to the region of cyclosporine involved in its immunosuppressive activity

FK 506-Binding Protein Proline Rotamase is a Target for the Immunosuppressive Agent FK 506 in Saccharomyces cerevisiae

Identification of several cyclosporine binding proteins in lymphoid and non-lymphoid cells in vivo

Prolactin as a Modulator of Lymphocyte Responsiveness Provides a Possible Mechanism of Action for Cyclosporine

A novel secreted cyclophilin-like protein (SCYLP)

SDZ PSC 833, A non‐immunosuppressive cyclosporine: Its potency in overcoming P‐glycoprotein‐mediated multidrug resistance of murine leukemia

Pharmacologic interactions between the resistance‐modifying cyclosporine sdz psc 833 and etoposide (VP 16–213) enhance In Vivo cytostatic activity and toxicity

Adenosine 3':5'-Monophosphate-dependent Protein Kinase and the Stimulation of Ovarian Nuclear Ribonucleic Acid Polymerase Activities

A comparison of cyclosporine binding by cyclophilin and calmodulin and the identification of a novel 45 KD cyclosporine-binding phosphoprotein in Jurkat cells

Dispholidus typus (boomslang) snake venom: Purification and properties of the coagulant principle

Immunomodulating activities of ethylene-2,2'-bis(dithio)bis(ethanol) and related compounds. Effects on murine lymphocyte proliferation and functions in vitro

MOLECULAR CHARACTERISTICS OF CYCLOPHILIN-CYCLOSPORINE INTERACTION

Mechanism of action of gonadotropin. IV. Cyclic adenosine monophosphate-dependent translocation of ovarian cytoplasmic cyclic adenosine monophosphate-binding protein and protein kinase to nuclear acceptor sites

Phosphorylation of myelin basic proteins: An age-dependent process affected by divalent cations and Co-Dergocrine (dihydroergotoxine)

Mechanism of Action of Gonadotropin. IV. Cyclic Adenosine Monophosphate-Dependent Translocation of Ovarian Cytoplasmic Cyclic Adenosine Monophosphate-Binding Protein and Protein Kinase to Nuclear Acceptor Sites 1

Mechanism of Action of Gonadotropin. III. Binding of Adenosine 3′,5′-Monophosphate by the 105,000 × g Supernatant Fraction from Homogenates of Calf Ovaries1

Early head‐to‐pelvis computed tomography in out‐of‐hospital circulatory arrest without obvious etiology

Studies on Adrenal Histones

Emergency Department Discharge of Pulmonary Embolus Patients

The Use of Very Low Concentrations of High‐sensitivity Troponin T to Rule Out Acute Myocardial Infarction Using a Single Blood Test

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