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M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

Oncoimmunology, 2018-05, Vol.7 (5), p.e1426519-e1426519

2018

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Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

Nature communications, 2021-08, Vol.12 (1), p.5151-5151, Article 5151

2021

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Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer

The Journal of clinical investigation, 2021-08, Vol.131 (16)

2021

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Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy

Journal for immunotherapy of cancer, 2019-03, Vol.7 (1), p.82-82, Article 82

2019

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Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein

PloS one, 2017-02, Vol.12 (2), p.e0171616-e0171616

2017

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Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

Oncoimmunology, 2018-11, Vol.7 (11), p.e1466018-e1466018

2018

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Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

Journal for immunotherapy of cancer, 2020-04, Vol.8 (1), p.e000493

2020

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Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies

Journal for immunotherapy of cancer, 2022-06, Vol.10 (6), p.e004561

2022

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Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced Stage Breast Cancer

Frontiers in oncology, 2021-03, Vol.10, p.581801-581801

2021

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Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

Oncoimmunology, 2021-01, Vol.10 (1), p.1915561-1915561

2021

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Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

The Journal of biological chemistry, 2011-12, Vol.286 (49), p.42027-42036

2011

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Myeloid Cell-Derived Oxidized Lipids and Regulation of the Tumor Microenvironment

Cancer research (Chicago, Ill.), 2022-01, Vol.82 (2), p.187-194

2022

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Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes

The Journal of biological chemistry, 2016-08, Vol.291 (32), p.16787-16801

2016

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Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy

Clinical cancer research, 2020-02, Vol.26 (3), p.704-716

2020

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Sprouty2 protein regulates hypoxia-inducible factor-α (HIFα) protein levels and transcription of HIFα-responsive genes

The Journal of biological chemistry, 2017-02, Vol.292 (7), p.3060-3060

2017

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Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy

Cancer immunology research, 2019-08, Vol.7 (8), p.1359-1370

2019

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Regulation of hypoxic responses by Sprouty2 in hepatocellular carcinoma

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer

The Journal of clinical investigation, 2021-08, Vol.131 (16), p.1-14

2021

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Abstract 1740: Epigenetic reprogramming of the tumor microenvironment by entinostat increases tumor sensitivity to multivalent immunotherapy combinations with an IL-15 superagonist plus vaccine or immune checkpoint blockade

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1740-1740

2018

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Abstract P034: Tumor-targeted interleukin-12 and Entinostat combination therapy improves cancer survival by reprogramming the tumor immune cell landscape

Cancer immunology research, 2022-01, Vol.10 (1_Supplement), p.P034-P034

2022

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The risk of incident extrahepatic cancers is higher in non-alcoholic fatty liver disease than obesity – A longitudinal cohort study

Journal of hepatology, 2019-12, Vol.71 (6), p.1229-1236

2019

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More than 50% of Clostridium difficile Isolates from Pet Dogs in Flagstaff, USA, Carry Toxigenic Genotypes

PloS one, 2016-10, Vol.11 (10), p.e0164504

2016

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Use of modified Magee equations and histologic criteria to predict the Oncotype DX recurrence score

Modern pathology, 2015-07, Vol.28 (7), p.921-931

2015

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A brief note on substantial sub-daily arsenic variability in pumping drinking-water wells in New Hampshire

The Science of the total environment, 2024-04, Vol.919, p.170838-170838, Article 170838

2024

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M7824, a novel bifunctional anti-PD-L1/TGFβ Trap fusion protein, promotes anti-tumor efficacy as monotherapy and in combination with vaccine

Tumour-targeted interleukin-12 and entinostat combination therapy improves cancer survival by reprogramming the tumour immune cell landscape

Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer

Mechanisms involved in IL-15 superagonist enhancement of anti-PD-L1 therapy

Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein

Epigenetic priming of both tumor and NK cells augments antibody-dependent cellular cytotoxicity elicited by the anti-PD-L1 antibody avelumab against multiple carcinoma cell types

Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist

Tumor-targeted interleukin-12 synergizes with entinostat to overcome PD-1/PD-L1 blockade-resistant tumors harboring MHC-I and APM deficiencies

Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced Stage Breast Cancer

Analysis of the tumor microenvironment and anti-tumor efficacy of subcutaneous vs systemic delivery of the bifunctional agent bintrafusp alfa

Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

Myeloid Cell-Derived Oxidized Lipids and Regulation of the Tumor Microenvironment

Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes

Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy

Sprouty2 protein regulates hypoxia-inducible factor-α (HIFα) protein levels and transcription of HIFα-responsive genes

Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy

Regulation of hypoxic responses by Sprouty2 in hepatocellular carcinoma

Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer

Abstract 1740: Epigenetic reprogramming of the tumor microenvironment by entinostat increases tumor sensitivity to multivalent immunotherapy combinations with an IL-15 superagonist plus vaccine or immune checkpoint blockade

Abstract P034: Tumor-targeted interleukin-12 and Entinostat combination therapy improves cancer survival by reprogramming the tumor immune cell landscape

The risk of incident extrahepatic cancers is higher in non-alcoholic fatty liver disease than obesity – A longitudinal cohort study

More than 50% of Clostridium difficile Isolates from Pet Dogs in Flagstaff, USA, Carry Toxigenic Genotypes

Recognize fish as food in policy discourse and development funding

Use of modified Magee equations and histologic criteria to predict the Oncotype DX recurrence score

A brief note on substantial sub-daily arsenic variability in pumping drinking-water wells in New Hampshire

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