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Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis

Journal of clinical oncology, 2005-02, Vol.23 (5), p.1011-1027

2005

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Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular Oncology

Clinical cancer research, 2009-12, Vol.15 (24), p.7471-7478

2009

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Pathways Mediating Resistance to Vascular Endothelial Growth Factor–Targeted Therapy

Clinical cancer research, 2008-10, Vol.14 (20), p.6371-6375

2008

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Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

Cancer cell, 2005-10, Vol.8 (4), p.299-309

2005

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Antiangiogenic therapy--evolving view based on clinical trial results

Nature reviews. Clinical oncology, 2012-05, Vol.9 (5), p.297-303

2012

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

Cancer research (Chicago, Ill.), 2006-02, Vol.66 (3), p.1500-1508

2006

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Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (8), p.3560-3564

2007

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Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

Cancer research (Chicago, Ill.), 2004-06, Vol.64 (11), p.3731-3736

2004

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Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors

Science (American Association for the Advancement of Science), 2006-09, Vol.313 (5794), p.1785-1787

2006

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Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4 + hemangiocytes

Nature medicine, 2006-05, Vol.12 (5), p.557-567

2006

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Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells

Oncogene, 2005-04, Vol.24 (16), p.2647-2653

2005

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Granulocyte colony‐stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils

The FASEB journal, 2005-12, Vol.19 (14), p.2005-2007

2005

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VEGF-targeted therapy: mechanisms of anti-tumour activity

Nature reviews. Cancer, 2008-08, Vol.8 (8), p.579-591

2008

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The vascular endothelial growth factor receptor (VEGFR‐1) supports growth and survival of human breast carcinoma

International journal of cancer, 2006-10, Vol.119 (7), p.1519-1529

2006

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Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.46-51

2006

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Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization

The Journal of experimental medicine, 2005-09, Vol.202 (6), p.739-750

2005

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Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

Nature medicine, 2002-08, Vol.8 (8), p.831-840

2002

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Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) Functions to Promote Uterine Decidual Angiogenesis during Early Pregnancy in the Mouse

Endocrinology (Philadelphia), 2009-08, Vol.150 (8), p.3845-3854

2009

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Review: Monoclonal Antibodies to the Vascular Endothelial Growth Factor Receptor-2 in Cancer Therapy

Clinical cancer research, 2007-09, Vol.13 (18), p.5544s-5548s

2007

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A Vascular Endothelial Growth Factor Receptor-2 Inhibitor Enhances Antitumor Immunity through an Immune-Based Mechanism

Clinical cancer research, 2007-07, Vol.13 (13), p.3951-3959

2007

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Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1 + stem cells from bone-marrow microenvironment

Nature medicine, 2002-08, Vol.8 (8), p.841-849

2002

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Vascular endothelial growth factor receptor‐1 promotes migration and invasion in pancreatic carcinoma cell lines

Cancer, 2005-07, Vol.104 (2), p.427-438

2005

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Monoclonal Antibody Cetuximab Binds to and Down-regulates Constitutively Activated Epidermal Growth Factor Receptor vIII on the Cell Surface

Anticancer research, 2007-09, Vol.27 (5A), p.3355-3366

2007

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Enhanced Antitumor Activity of Anti-epidermal Growth Factor Receptor Monoclonal Antibody IMC-C225 in Combination with Irinotecan (CPT-11) against Human Colorectal Tumor Xenografts

Clinical cancer research, 2002-05, Vol.8 (5), p.994-1003

2002

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Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis

Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular Oncology

Pathways Mediating Resistance to Vascular Endothelial Growth Factor–Targeted Therapy

Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

Antiangiogenic therapy--evolving view based on clinical trial results

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

Anticancer therapies combining antiangiogenic and tumor cell cytotoxic effects reduce the tumor stem-like cell fraction in glioma xenograft tumors

Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors

Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors

Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4 + hemangiocytes

Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells

Granulocyte colony‐stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils

VEGF-targeted therapy: mechanisms of anti-tumour activity

The vascular endothelial growth factor receptor (VEGFR‐1) supports growth and survival of human breast carcinoma

Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells

Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMP-9-mediated progenitor cell mobilization

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) Functions to Promote Uterine Decidual Angiogenesis during Early Pregnancy in the Mouse

Review: Monoclonal Antibodies to the Vascular Endothelial Growth Factor Receptor-2 in Cancer Therapy

A Vascular Endothelial Growth Factor Receptor-2 Inhibitor Enhances Antitumor Immunity through an Immune-Based Mechanism

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1 + stem cells from bone-marrow microenvironment

Vascular endothelial growth factor receptor‐1 promotes migration and invasion in pancreatic carcinoma cell lines

Monoclonal Antibody Cetuximab Binds to and Down-regulates Constitutively Activated Epidermal Growth Factor Receptor vIII on the Cell Surface

Enhanced Antitumor Activity of Anti-epidermal Growth Factor Receptor Monoclonal Antibody IMC-C225 in Combination with Irinotecan (CPT-11) against Human Colorectal Tumor Xenografts

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