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Preclinical trials in Alzheimer's disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

PloS one, 2023-04, Vol.18 (4), p.e0281003-e0281003

2023

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Miro proteins prime mitochondria for Parkin translocation and mitophagy

The EMBO journal, 2019-01, Vol.38 (2), p.n/a

2019

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ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome

Nature communications, 2024-07, Vol.15 (1), p.6143-18, Article 6143

2024

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Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration

Scientific reports, 2017-08, Vol.7 (1), p.10220-10220, Article 10220

2017

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Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease

Molecular neurodegeneration, 2012-04, Vol.7 (1), p.12-12, Article 12

2012

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No Evidence of Sensory Neuropathy in a Traditional Mouse Model of Idiopathic Parkinson's Disease

Cells (Basel, Switzerland), 2024-05, Vol.13 (10), p.799

2024

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Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype

Cells (Basel, Switzerland), 2021-11, Vol.10 (11), p.3193

2021

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Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy

Autophagy, 2019-05, Vol.15 (5), p.930-931

2019

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BECN1 is involved in the initiation of mitophagy: It facilitates PARK2 translocation to mitochondria

Autophagy, 2014-06, Vol.10 (6), p.1105-1119

2014

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Mutant huntingtin-impaired degradation of β-catenin causes neurotoxicity in Huntington's disease

The EMBO journal, 2010-07, Vol.29 (14), p.2433-2445

2010

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The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease

Journal of neurochemistry, 2002-04, Vol.81 (1), p.46-59

2002

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Phenotype onset in Huntington’s disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene

Journal of neuroscience research, 2019-12, Vol.97 (12), p.1590-1605

2019

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Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models

Human molecular genetics, 2009-03, Vol.18 (6), p.1006-1016

2009

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Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders

Scientific reports, 2019-04, Vol.9 (1), p.5457-5457, Article 5457

2019

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A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease

Journal of neurophysiology, 2012-01, Vol.107 (2), p.677-691

2012

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Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease

Brain research bulletin, 2012-04, Vol.87 (6), p.571-578

2012

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Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect

Trends in neurosciences (Regular ed.), 2004-11, Vol.27 (11), p.691-697

2004

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Apoptosis in Huntington's disease

Progress in neuro-psychopharmacology & biological psychiatry, 2003-04, Vol.27 (2), p.255-265

2003

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Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease

Molecular and cellular neuroscience, 2012-02, Vol.49 (2), p.149-157

2012

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Methamphetamine toxicity in mice is potentiated by exposure to loud music

Neuroreport, 2001-10, Vol.12 (15), p.3277-3281

2001

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Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics

Chemical research in toxicology, 2021-05, Vol.34 (5), p.1223-1239

2021

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Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and Ampakines

PLoS currents, 2010-09, Vol.2, p.RRN1182

2010

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Mice Transgenic for the Huntington's Disease Mutation Are Resistant to Chronic 3‐Nitropropionic Acid‐Induced Striatal Toxicity

Journal of neurochemistry, 2000-11, Vol.75 (5), p.2163-2171

2000

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Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

Neuroscience, 2008-11, Vol.157 (1), p.280-295

2008

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Preclinical trials in Alzheimer's disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

PloS one, 2023-01, Vol.18 (4), p.e0281003

2023

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Preclinical trials in Alzheimer's disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

Miro proteins prime mitochondria for Parkin translocation and mitophagy

ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome

Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration

Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease

No Evidence of Sensory Neuropathy in a Traditional Mouse Model of Idiopathic Parkinson's Disease

Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype

Mitochondrial transport proteins RHOT1 and RHOT2 serve as docking sites for PRKN-mediated mitophagy

BECN1 is involved in the initiation of mitophagy: It facilitates PARK2 translocation to mitochondria

Mutant huntingtin-impaired degradation of β-catenin causes neurotoxicity in Huntington's disease

The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease

Phenotype onset in Huntington’s disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene

Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models

Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders

A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease

Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease

Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect

Apoptosis in Huntington's disease

Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease

Methamphetamine toxicity in mice is potentiated by exposure to loud music

Using Rotenone to Model Parkinson’s Disease in Mice: A Review of the Role of Pharmacokinetics

Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and Ampakines

Mice Transgenic for the Huntington's Disease Mutation Are Resistant to Chronic 3‐Nitropropionic Acid‐Induced Striatal Toxicity

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

Preclinical trials in Alzheimer's disease: Sample size and effect size for behavioural and neuropathological outcomes in 5xFAD mice

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