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Keratin 16 regulates innate immunity in response to epidermal barrier breach

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19537-19542

2013

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In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles

ACS nano, 2011-12, Vol.5 (12), p.9977-9983

2011

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Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (33), p.13171-13176

2012

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First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder

Molecular therapy, 2010-02, Vol.18 (2), p.442-446

2010

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Following movement of the L1 stalk between three functional states in single ribosomes

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2571-2576

2009

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Therapeutic Prospects of Exon Skipping for Epidermolysis Bullosa

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12222

2021

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Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita

Journal of dermatological science, 2008-09, Vol.51 (3), p.151-157

2008

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The antibiotic viomycin traps the ribosome in an intermediate state of translocation

Nature structural & molecular biology, 2007-06, Vol.14 (6), p.493-497

2007

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Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients

Journal of dermatological science, 2009-11, Vol.56 (2), p.82-88

2009

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A Tensioned Human Skin Explant Model Used for Preliminary Assessment of Chemexfoliant-Stimulated Bioeffects

JID innovations, 2025-01, Vol.5 (1), p.100305, Article 100305

2025

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Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model

Journal of investigative dermatology, 2011-05, Vol.131 (5), p.1037-1044

2011

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Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays

Human gene therapy, 2012-08, Vol.23 (8), p.816-823

2012

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Gene expression profiling in pachyonychia congenita skin

Journal of dermatological science, 2015-03, Vol.77 (3), p.156-165

2015

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Development of Therapeutic siRNAs for Pachyonychia Congenita

Journal of investigative dermatology, 2008-01, Vol.128 (1), p.50-58

2008

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mRNA Helicase Activity of the Ribosome

Cell, 2005-01, Vol.120 (1), p.49-58

2005

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Pachyonychia Congenita: A Research Agenda Leading to New Therapeutic Approaches

Journal of investigative dermatology, 2024-04, Vol.144 (4), p.748-754

2024

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Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding

RNA (Cambridge), 2009-08, Vol.15 (8), p.1597-1604

2009

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Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device

Molecular therapy. Nucleic acids, 2013-10, Vol.2 (10), p.e129-e129, Article e129

2013

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Sequence and Stacking Dependence of 8-Oxoguanine Oxidation: Comparison of One-Electron vs Singlet Oxygen Mechanisms

Journal of the American Chemical Society, 1999-10, Vol.121 (40), p.9423-9428

1999

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Observation of Intersubunit Movement of the Ribosome in Solution Using FRET

Journal of molecular biology, 2007-07, Vol.370 (3), p.530-540

2007

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In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

Journal of controlled release, 2014-12, Vol.196, p.355-362

2014

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Silencing of Reporter Gene Expression in Skin Using siRNAs and Expression of Plasmid DNA Delivered by a Soluble Protrusion Array Device (PAD)

Molecular therapy, 2010-09, Vol.18 (9), p.1667-1674

2010

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Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy

Human molecular genetics, 2016-03, Vol.25 (6), p.1176-1191

2016

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Single-Nucleotide-Specific siRNA Targeting in a Dominant-Negative Skin Model

Journal of investigative dermatology, 2008-03, Vol.128 (3), p.594-605

2008

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Development of Skin-Humanized Mouse Models of Pachyonychia Congenita

Journal of investigative dermatology, 2011-05, Vol.131 (5), p.1053-1060

2011

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Keratin 16 regulates innate immunity in response to epidermal barrier breach

In Vivo Sustained Release of siRNA from Solid Lipid Nanoparticles

Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells

First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder

Following movement of the L1 stalk between three functional states in single ribosomes

Therapeutic Prospects of Exon Skipping for Epidermolysis Bullosa

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita

The antibiotic viomycin traps the ribosome in an intermediate state of translocation

Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients

A Tensioned Human Skin Explant Model Used for Preliminary Assessment of Chemexfoliant-Stimulated Bioeffects

Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model

Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays

Gene expression profiling in pachyonychia congenita skin

Development of Therapeutic siRNAs for Pachyonychia Congenita

mRNA Helicase Activity of the Ribosome

Pachyonychia Congenita: A Research Agenda Leading to New Therapeutic Approaches

Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding

Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device

Sequence and Stacking Dependence of 8-Oxoguanine Oxidation: Comparison of One-Electron vs Singlet Oxygen Mechanisms

Observation of Intersubunit Movement of the Ribosome in Solution Using FRET

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

Silencing of Reporter Gene Expression in Skin Using siRNAs and Expression of Plasmid DNA Delivered by a Soluble Protrusion Array Device (PAD)

Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy

Single-Nucleotide-Specific siRNA Targeting in a Dominant-Negative Skin Model

Development of Skin-Humanized Mouse Models of Pachyonychia Congenita

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