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Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3

Cancer research (Chicago, Ill.), 2017-03, Vol.77 (6), p.1283-1295

2017

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Cancer–nerve interplay in cancer progression and cancer-induced bone pain

Journal of bone and mineral metabolism, 2023-05, Vol.41 (3), p.415-427

2023

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Contribution of acidic extracellular microenvironment of cancer-colonized bone to bone pain

Biochimica et biophysica acta, 2015-10, Vol.1848 (10), p.2677-2684

2015

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Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis

Nature communications, 2022-11, Vol.13 (1), p.7194-7194, Article 7194

2022

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Pathogenesis and treatment of multiple myeloma bone disease

The Japanese dental science review, 2021-11, Vol.57, p.164-173

2021

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Myeloma–Bone Interaction: A Vicious Cycle via TAK1–PIM2 Signaling

Cancers, 2021-09, Vol.13 (17), p.4441

2021

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Sensory nerves: A driver of the vicious cycle in bone metastasis?

Journal of bone oncology, 2021-10, Vol.30, p.100387-100387, Article 100387

2021

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TAK1 is a pivotal therapeutic target for tumor progression and bone destruction in myeloma

Haematologica (Roma), 2021-05, Vol.106 (5), p.1401

2021

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Inflammatory Cytokine-Induced Muscle Atrophy and Weakness Can Be Ameliorated by an Inhibition of TGF-β-Activated Kinase-1

International journal of molecular sciences, 2024-06, Vol.25 (11), p.5715

2024

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Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth

PloS one, 2010-03, Vol.5 (3), p.e9870

2010

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Mechanical unloading aggravates bone destruction and tumor expansion in myeloma

Haematologica (Roma), 2021-11, Vol.107 (3), p.744

2021

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Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma

British journal of haematology, 2018-02, Vol.180 (4), p.581-585

2018

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The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat

Cancers, 2020-04, Vol.12 (4), p.929

2020

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The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

Journal of bone oncology, 2021-02, Vol.26, p.100330-100330, Article 100330

2021

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The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2

Antioxidants, 2023-01, Vol.12 (1), p.133

2023

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Synergistic targeting of Sp1, a critical transcription factor for myeloma cell growth and survival, by panobinostat and proteasome inhibitors

Oncotarget, 2016-10, Vol.7 (48), p.79064-79075

2016

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TGF‐β‐activated kinase‐1 inhibitor LL‐Z1640‐2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF‐α and RANKL expression

Clinical & translational immunology, 2022, Vol.11 (1), p.e1371-n/a

2022

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TAK1 inhibition effectively suppresses NLRP3 inflammasome-mediated inflammation and osteoclastic bone resorption in rheumatoid arthritis

Bone Reports, 2020-10, Vol.13, p.100635, Article 100635

2020

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Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction

Bone Reports, 2020-10, Vol.13, p.100425, Article 100425

2020

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The anti-SLAMF7 elotuzumab enhances ADCC activity with Th1-like γδT cells towards osteoclasts and myeloma cells

Bone Reports, 2021-04, Vol.14, p.100902, Article 100902

2021

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Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma

International journal of hematology, 2009-01, Vol.89 (1), p.45-57

2009

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Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib

International journal of hematology, 2013-07, Vol.98 (1), p.66-73

2013

Volltextzugriff (PDF)

Persistent Activation of Calcium‐Sensing Receptor Suppresses Bone Turnover, Increases Microcracks, and Decreases Bone Strength

JBMR plus, 2019-07, Vol.3 (7), p.e10182-n/a

2019

Volltextzugriff (PDF)

Delayed treatment with vitamin C and N-acetyl-l-cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib

International journal of hematology, 2011-06, Vol.93 (6), p.727-735

2011

Volltextzugriff (PDF)

Bone-fat linkage via interleukin-11 in response to mechanical loading

Journal of bone and mineral metabolism, 2024-02

2024

Volltextzugriff (PDF)

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Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3

Cancer–nerve interplay in cancer progression and cancer-induced bone pain

Contribution of acidic extracellular microenvironment of cancer-colonized bone to bone pain

Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis

Pathogenesis and treatment of multiple myeloma bone disease

Myeloma–Bone Interaction: A Vicious Cycle via TAK1–PIM2 Signaling

Sensory nerves: A driver of the vicious cycle in bone metastasis?

TAK1 is a pivotal therapeutic target for tumor progression and bone destruction in myeloma

Inflammatory Cytokine-Induced Muscle Atrophy and Weakness Can Be Ameliorated by an Inhibition of TGF-β-Activated Kinase-1

Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth

Mechanical unloading aggravates bone destruction and tumor expansion in myeloma

Pim‐2 is a critical target for treatment of osteoclastogenesis enhanced in myeloma

The Roles of ROS Generation in RANKL-Induced Osteoclastogenesis: Suppressive Effects of Febuxostat

The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2

Synergistic targeting of Sp1, a critical transcription factor for myeloma cell growth and survival, by panobinostat and proteasome inhibitors

TGF‐β‐activated kinase‐1 inhibitor LL‐Z1640‐2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF‐α and RANKL expression

TAK1 inhibition effectively suppresses NLRP3 inflammasome-mediated inflammation and osteoclastic bone resorption in rheumatoid arthritis

Mechanical unloading enhances bone destruction and tumor expansion in multiple myeloma: Critical roles of osteocytic RANKL induction

The anti-SLAMF7 elotuzumab enhances ADCC activity with Th1-like γδT cells towards osteoclasts and myeloma cells

Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma

Activating transcription factor 4, an ER stress mediator, is required for, but excessive ER stress suppresses osteoblastogenesis by bortezomib

Persistent Activation of Calcium‐Sensing Receptor Suppresses Bone Turnover, Increases Microcracks, and Decreases Bone Strength

Delayed treatment with vitamin C and N-acetyl-l-cysteine protects Schwann cells without compromising the anti-myeloma activity of bortezomib

Bone-fat linkage via interleukin-11 in response to mechanical loading

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