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Biochemistry and regulation of the protein arginine methyltransferases (PRMTs)

Archives of biochemistry and biophysics, 2016-01, Vol.590, p.138-152

2016

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Toward Understanding Molecular Recognition between PRMTs and their Substrates

Current protein & peptide science, 2020-01, Vol.21 (7), p.713-724

2020

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Redox Control of Protein Arginine Methyltransferase 1 (PRMT1) Activity

The Journal of biological chemistry, 2015-06, Vol.290 (24), p.14915-14926

2015

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Structural Determinants for the Strict Monomethylation Activity by Trypanosoma brucei Protein Arginine Methyltransferase 7

Structure (London), 2014-05, Vol.22 (5), p.756-768

2014

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Substrate-Induced Control of Product Formation by Protein Arginine Methyltransferase 1

Biochemistry (Easton), 2013-01, Vol.52 (1), p.199-209

2013

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Examining Product Specificity in Protein Arginine Methyltransferase 7 (PRMT7) Using Quantum and Molecular Mechanical Simulations

Journal of chemical information and modeling, 2019-06, Vol.59 (6), p.2913-2923

2019

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Rapid and direct measurement of methyltransferase activity in about 30 min

Methods (San Diego, Calif.), 2020-03, Vol.175, p.3-9

2020

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Naturally occurring cancer-associated mutations disrupt oligomerization and activity of protein arginine methyltransferase 1 (PRMT1)

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101336, Article 101336

2021

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Oligomerization of protein arginine methyltransferase 1 and its effect on methyltransferase activity and substrate specificity

Protein science, 2024-08, Vol.33 (8), p.e5118-n/a

2024

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Sequence analysis and biochemical characterization of the nostopeptolide A biosynthetic gene cluster from Nostoc sp. GSV224

Gene, 2003-06, Vol.311, p.171-180

2003

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Informatics and Computational Approaches for the Discovery and Optimization of Natural Product-Inspired Inhibitors of the SARS-CoV‑2 2′‑O‑Methyltransferase

Journal of natural products (Washington, D.C.), 2024-02, Vol.87 (2), p.217-227

2024

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A Remodeled Protein Arginine Methyltransferase 1 (PRMT1) Generates Symmetric Dimethylarginine

The Journal of biological chemistry, 2014-03, Vol.289 (13), p.9320-9327

2014

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Understanding protein arginine methyltransferase 1 (PRMT1) product specificity from molecular dynamics

Bioorganic & medicinal chemistry, 2016-10, Vol.24 (20), p.4949-4960

2016

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Phe71 in Type III Trypanosomal Protein Arginine Methyltransferase 7 (TbPRMT7) Restricts the Enzyme to Monomethylation

Biochemistry (Easton), 2018-02, Vol.57 (8), p.1349-1359

2018

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Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions

BMC genomics, 2008-08, Vol.9 (1), p.376-376

2008

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Biosynthesis of 4-Methylproline in Cyanobacteria: Cloning of nosE and nosF Genes and Biochemical Characterization of the Encoded Dehydrogenase and Reductase Activities

Journal of organic chemistry, 2003-01, Vol.68 (1), p.83-91

2003

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Substrate Profiling of PRMT1 Reveals Amino Acid Sequences That Extend Beyond the “RGG” Paradigm

Biochemistry (Easton), 2008-09, Vol.47 (36), p.9456-9466

2008

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A fast and efficient method for quantitative measurement of S-adenosyl- l-methionine-dependent methyltransferase activity with protein substrates

Analytical biochemistry, 2010-03, Vol.398 (2), p.218-224

2010

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An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases

Analytical biochemistry, 2006-03, Vol.350 (2), p.249-255

2006

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Investigation of the Molecular Origins of Protein-arginine Methyltransferase I (PRMT1) Product Specificity Reveals a Role for Two Conserved Methionine Residues

The Journal of biological chemistry, 2011-08, Vol.286 (33), p.29118-29126

2011

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Mutation of a Strictly Conserved, Active-Site Residue Alters Substrate Specificity and Cofactor Biogenesis in a Copper Amine Oxidase

Biochemistry (Easton), 1999-03, Vol.38 (12), p.3683-3693

1999

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Efficient cleavage of problematic tobacco etch virus (TEV)–protein arginine methyltransferase constructs

Analytical biochemistry, 2009-04, Vol.387 (1), p.130-132

2009

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Macrophage nitric oxide synthase: relationship between enzyme-bound tetrahydrobiopterin and synthase activity

Biochemistry (Easton), 1992-08, Vol.31 (31), p.7160-7165

1992

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Can the DCoHα isozyme compensate in patients with 4a-hydroxy-tetrahydrobiopterin dehydratase/DCoH deficiency?

Molecular genetics and metabolism, 2006-05, Vol.88 (1), p.38-46

2006

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Biosynthesis of 4-Methylproline in Cyanobacteria: Cloning of n osE and n osF Genes and Biochemical Characterization of the Encoded Dehydrogenase and Reductase Activities

Journal of organic chemistry, 2003-01, Vol.68 (1), p.83-91

2003

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Biochemistry and regulation of the protein arginine methyltransferases (PRMTs)

Toward Understanding Molecular Recognition between PRMTs and their Substrates

Redox Control of Protein Arginine Methyltransferase 1 (PRMT1) Activity

Structural Determinants for the Strict Monomethylation Activity by Trypanosoma brucei Protein Arginine Methyltransferase 7

Substrate-Induced Control of Product Formation by Protein Arginine Methyltransferase 1

Examining Product Specificity in Protein Arginine Methyltransferase 7 (PRMT7) Using Quantum and Molecular Mechanical Simulations

Rapid and direct measurement of methyltransferase activity in about 30 min

Naturally occurring cancer-associated mutations disrupt oligomerization and activity of protein arginine methyltransferase 1 (PRMT1)

Oligomerization of protein arginine methyltransferase 1 and its effect on methyltransferase activity and substrate specificity

Sequence analysis and biochemical characterization of the nostopeptolide A biosynthetic gene cluster from Nostoc sp. GSV224

Informatics and Computational Approaches for the Discovery and Optimization of Natural Product-Inspired Inhibitors of the SARS-CoV‑2 2′‑O‑Methyltransferase

A Remodeled Protein Arginine Methyltransferase 1 (PRMT1) Generates Symmetric Dimethylarginine

Understanding protein arginine methyltransferase 1 (PRMT1) product specificity from molecular dynamics

Phe71 in Type III Trypanosomal Protein Arginine Methyltransferase 7 (TbPRMT7) Restricts the Enzyme to Monomethylation

Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions

Biosynthesis of 4-Methylproline in Cyanobacteria: Cloning of nosE and nosF Genes and Biochemical Characterization of the Encoded Dehydrogenase and Reductase Activities

Substrate Profiling of PRMT1 Reveals Amino Acid Sequences That Extend Beyond the “RGG” Paradigm

A fast and efficient method for quantitative measurement of S-adenosyl- l-methionine-dependent methyltransferase activity with protein substrates

An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases

Investigation of the Molecular Origins of Protein-arginine Methyltransferase I (PRMT1) Product Specificity Reveals a Role for Two Conserved Methionine Residues

Mutation of a Strictly Conserved, Active-Site Residue Alters Substrate Specificity and Cofactor Biogenesis in a Copper Amine Oxidase

Efficient cleavage of problematic tobacco etch virus (TEV)–protein arginine methyltransferase constructs

Macrophage nitric oxide synthase: relationship between enzyme-bound tetrahydrobiopterin and synthase activity

Can the DCoHα isozyme compensate in patients with 4a-hydroxy-tetrahydrobiopterin dehydratase/DCoH deficiency?

Biosynthesis of 4-Methylproline in Cyanobacteria: Cloning of n osE and n osF Genes and Biochemical Characterization of the Encoded Dehydrogenase and Reductase Activities

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