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Innovative preclinical models for pulmonary drug delivery research

Expert opinion on drug delivery, 2020-04, Vol.17 (4), p.463-478

2020

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Inhaled IgG1 antibodies: The buffering system is an important driver of stability during mesh-nebulization

European journal of pharmaceutics and biopharmaceutics, 2022-12, Vol.181, p.173-182

2022

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Inhalation of Immuno-Therapeutics/-Prophylactics to Fight Respiratory Tract Infections: An Appropriate Drug at the Right Place

Frontiers in immunology, 2019-11, Vol.10, p.2760-2760

2019

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Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

The Journal of biological chemistry, 2016-04, Vol.291 (16), p.8486-8499

2016

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Angiogenesis stimulated by human kallikrein‐related peptidase 12 acting via a platelet‐derived growth factor B‐dependent paracrine pathway

The FASEB journal, 2014-02, Vol.28 (2), p.740-751

2014

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Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis

The European respiratory journal, 2016-04, Vol.47 (4), p.1277-1280

2016

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Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis

mAbs, 2019-02, Vol.11 (2), p.297-304

2019

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Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment

Frontiers in immunology, 2018-09, Vol.9, p.2259-2259

2018

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Protein stability during nebulization: Mind the collection step

European journal of pharmaceutics and biopharmaceutics, 2020-07, Vol.152, p.23-34

2020

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Influence of mesh nebulizer characteristics on aerosol delivery in non-human primates

European journal of pharmaceutical sciences, 2023-12, Vol.191, p.106606-106606, Article 106606

2023

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Aerosol Therapy in Adults Receiving High Flow Nasal Cannula Oxygen Therapy

Journal of aerosol medicine and pulmonary drug delivery, 2016-04, Vol.29 (2), p.134

2016

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Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8

PloS one, 2012, Vol.7 (1), p.e30601-e30601

2012

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Mucosal administration of anti-bacterial antibodies provide long-term cross-protection against Pseudomonas aeruginosa respiratory infection

Mucosal immunology, 2023-06, Vol.16 (3), p.312-325

2023

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Designing inhaled protein therapeutics for topical lung delivery: what are the next steps?

Expert opinion on drug delivery, 2018-08, Vol.15 (8), p.729-736

2018

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Nebulization as a delivery method for mAbs in respiratory diseases

Expert opinion on drug delivery, 2015-06, Vol.12 (6), p.1027-1039

2015

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Barriers for orally inhaled therapeutic antibodies

Expert opinion on drug delivery, 2023-08, Vol.20 (8), p.1071-1084

2023

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Nasal high flow nebulization in infants and toddlers: An in vitro and in vivo scintigraphic study

Pediatric pulmonology, 2017-03, Vol.52 (3), p.337-344

2017

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Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response

Mucosal immunology, 2020-01, Vol.13 (1), p.128-139

2020

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Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation

British journal of pharmacology, 2021-09, Vol.178 (18), p.3829-3842

2021

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Inhalable Nanofitin demonstrates high neutralization of SARS-CoV-2 virus via direct application in respiratory tract

Molecular therapy, 2023-10, Vol.31 (10), p.2861-2871

2023

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Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung

Biological chemistry, 2008-06, Vol.389 (6), p.781-786

2008

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The proteolytic airway environment associated with pneumonia acts as a barrier for treatment with anti-infective antibodies

European journal of pharmaceutics and biopharmaceutics, 2024-02, Vol.195, p.114163-114163, Article 114163

2024

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Therapeutic antibodies – natural and pathological barriers and strategies to overcome them

Pharmacology & therapeutics (Oxford), 2022-05, Vol.233, p.108022-108022, Article 108022

2022

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Alternative Routes of Administration for Therapeutic Antibodies—State of the Art

Antibodies (Basel), 2022-08, Vol.11 (3), p.56

2022

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Innovative preclinical models for pulmonary drug delivery research

Inhaled IgG1 antibodies: The buffering system is an important driver of stability during mesh-nebulization

Inhalation of Immuno-Therapeutics/-Prophylactics to Fight Respiratory Tract Infections: An Appropriate Drug at the Right Place

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

Angiogenesis stimulated by human kallikrein‐related peptidase 12 acting via a platelet‐derived growth factor B‐dependent paracrine pathway

Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis

Exploring the fate of inhaled monoclonal antibody in the lung parenchyma by microdialysis

Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment

Protein stability during nebulization: Mind the collection step

Influence of mesh nebulizer characteristics on aerosol delivery in non-human primates

Aerosol Therapy in Adults Receiving High Flow Nasal Cannula Oxygen Therapy

Inhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8

Mucosal administration of anti-bacterial antibodies provide long-term cross-protection against Pseudomonas aeruginosa respiratory infection

Designing inhaled protein therapeutics for topical lung delivery: what are the next steps?

Nebulization as a delivery method for mAbs in respiratory diseases

Barriers for orally inhaled therapeutic antibodies

Nasal high flow nebulization in infants and toddlers: An in vitro and in vivo scintigraphic study

Interleukin-7 protects against bacterial respiratory infection by promoting IL-17A-producing innate T-cell response

Inhaled bacteriophage therapy in a porcine model of pneumonia caused by Pseudomonas aeruginosa during mechanical ventilation

Inhaled Amikacin to Prevent Ventilator-Associated Pneumonia

Inhalable Nanofitin demonstrates high neutralization of SARS-CoV-2 virus via direct application in respiratory tract

Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung

The proteolytic airway environment associated with pneumonia acts as a barrier for treatment with anti-infective antibodies

Therapeutic antibodies – natural and pathological barriers and strategies to overcome them

Alternative Routes of Administration for Therapeutic Antibodies—State of the Art

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