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Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Nature reviews. Endocrinology, 2016-11, Vol.12 (11), p.633-645

2016

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Exercising your fat (metabolism) into shape: a muscle-centred view

Diabetologia, 2020-08, Vol.63 (8), p.1453-1463

2020

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Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes

Diabetologia, 2017-03, Vol.60 (3), p.490-498

2017

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Effects of exercise training on intrahepatic lipid content in humans

Diabetologia, 2016-10, Vol.59 (10), p.2068-2079

2016

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Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

Diabetologia, 2021-02, Vol.64 (2), p.424-436

2021

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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

Nature communications, 2022-06, Vol.13 (1), p.3508-3508, Article 3508

2022

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Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Cell metabolism, 2011-11, Vol.14 (5), p.612-622

2011

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Timing of physical activity in relation to liver fat content and insulin resistance

Diabetologia, 2023-03, Vol.66 (3), p.461-471

2023

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Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

The journal of clinical endocrinology and metabolism, 2013-04, Vol.98 (4), p.1694-1702

2013

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Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.572-579

2010

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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7789-7794

2018

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Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

Diabetes (New York, N.Y.), 2008-11, Vol.57 (11), p.2943-2949

2008

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Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial

Diabetes care, 2016-12, Vol.39 (12), p.2211-2217

2016

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Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Diabetes (New York, N.Y.), 2012-11, Vol.61 (11), p.2679-2690

2012

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Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetes

Diabetologia, 2020-12, Vol.63 (12), p.2654-2664

2020

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ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure

eLife, 2015-10, Vol.4

2015

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The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

Histochemistry and cell biology, 2012-02, Vol.137 (2), p.205-216

2012

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Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

Diabetes (New York, N.Y.), 2010-09, Vol.59 (9), p.2117-2125

2010

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Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?

Annals of the New York Academy of Sciences, 2013-07, Vol.1290 (1), p.83-89

2013

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The effect of diet and exercise on lipid droplet dynamics in human muscle tissue

Journal of experimental biology, 2018-03, Vol.221 (Pt Suppl 1)

2018

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PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans

Scientific reports, 2023-05, Vol.13 (1), p.8346-8346, Article 8346

2023

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Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial

Diabetes care, 2021-06, Vol.44 (6), p.1334-1343

2021

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Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing

Obesity (Silver Spring, Md.), 2020-07, Vol.28 (S1), p.S38-S45

2020

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Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (29), p.11711-11716

2012

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The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity

International Journal of Obesity, 2021-07, Vol.45 (7), p.1510-1520

2021

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Skeletal muscle mitochondria as a target to prevent or treat type 2 diabetes mellitus

Exercising your fat (metabolism) into shape: a muscle-centred view

Breaking sitting with light activities vs structured exercise: a randomised crossover study demonstrating benefits for glycaemic control and insulin sensitivity in type 2 diabetes

Effects of exercise training on intrahepatic lipid content in humans

Human skeletal muscle mitochondrial dynamics in relation to oxidative capacity and insulin sensitivity

A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Timing of physical activity in relation to liver fat content and insulin resistance

Nine Months of Combined Training Improves Ex Vivo Skeletal Muscle Metabolism in Individuals With Type 2 Diabetes

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial

Perilipin 2 Improves Insulin Sensitivity in Skeletal Muscle Despite Elevated Intramuscular Lipid Levels

Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetes

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria

Prolonged Fasting Identifies Skeletal Muscle Mitochondrial Dysfunction as Consequence Rather Than Cause of Human Insulin Resistance

Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?

The effect of diet and exercise on lipid droplet dynamics in human muscle tissue

PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans

Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial

Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing

Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity

The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity

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