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Structure elucidation of colibactin and its DNA cross-links

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6457)

2019

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A Method for the Selective Hydrogenation of Alkenyl Halides to Alkyl Halides

Journal of the American Chemical Society, 2014-05, Vol.136 (19), p.6884-6887

2014

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Non-classical selectivities in the reduction of alkenes by cobalt-mediated hydrogen atom transfer

Chemical science (Cambridge), 2015-01, Vol.6 (11), p.6250-6255

2015

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On the Abundance and Stability of Diazo-Containing Secondary Metabolites: Enantioselective Synthesis of (−)-Nenestatin A

Organic letters, 2023-05, Vol.25 (20), p.3723-3727

2023

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A modular and enantioselective synthesis of the pleuromutilin antibiotics

Science (American Association for the Advancement of Science), 2017-06, Vol.356 (6341), p.956-959

2017

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Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway

Journal of the American Chemical Society, 2021-12, Vol.143 (48), p.20332-20342

2021

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Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective

Journal of the American Chemical Society, 2017-10, Vol.139 (42), p.14817-14824

2017

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Synthesis of Ketones and Esters from Heteroatom-Functionalized Alkenes by Cobalt-Mediated Hydrogen Atom Transfer

Journal of organic chemistry, 2016-10, Vol.81 (19), p.8673-8695

2016

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Development of a Modular Synthetic Route to (+)-Pleuromutilin, (+)-12-epi-Mutilins, and Related Structures

Journal of the American Chemical Society, 2017-11, Vol.139 (45), p.16377-16388

2017

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Metric-Based Analysis of Convergence in Complex Molecule Synthesis

Accounts of chemical research, 2021-02, Vol.54 (4), p.903-916

2021

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Depurination of Colibactin-Derived Interstrand Cross-Links

Biochemistry (Easton), 2020-02, Vol.59 (7), p.892-900

2020

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A Mechanistic Model for Colibactin-Induced Genotoxicity

Journal of the American Chemical Society, 2016-12, Vol.138 (48), p.15563-15570

2016

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Temporal separation of catalytic activities allows anti-Markovnikov reductive functionalization of terminal alkynes

Nature chemistry, 2014-01, Vol.6 (1), p.22-27

2014

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Regioselective Reductive Hydration of Alkynes To Form Branched or Linear Alcohols

Journal of the American Chemical Society, 2012-10, Vol.134 (42), p.17376-17379

2012

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A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials

Nature (London), 2015-09, Vol.525 (7570), p.507-510

2015

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Synthesis of 1,3-Amino Alcohols, 1,3-Diols, Amines, and Carboxylic Acids from Terminal Alkynes

Journal of organic chemistry, 2015-09, Vol.80 (17), p.8604-8618

2015

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Broad-Spectrum Catalysts for the Ambient Temperature Anti-Markovnikov Hydration of Alkynes

Angewandte Chemie (International ed.), 2014-07, Vol.53 (30), p.7892-7895

International ed. in English, 2014

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Characterization of Natural Colibactin–Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening

Biochemistry (Easton), 2018-11, Vol.57 (45), p.6391-6394

2018

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Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A

Journal of the American Chemical Society, 2016-04, Vol.138 (16), p.5426-5432

2016

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Intermolecular Hydropyridylation of Unactivated Alkenes

Journal of the American Chemical Society, 2016-07, Vol.138 (28), p.8718-8721

2016

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Synthesis and reactivity of precolibactin 886

Nature chemistry, 2019-10, Vol.11 (10), p.890-898

2019

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Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis

Journal of the American Chemical Society, 2017-03, Vol.139 (11), p.4195-4201

2017

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Development of an Enantioselective Synthesis of (−)-Euonyminol

Journal of organic chemistry, 2021-12, Vol.86 (23), p.17011-17035

2021

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The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors

Neoplasia (New York, N.Y.), 2023-09, Vol.43, p.100918-100918, Article 100918

2023

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New Leads for the Treatment of Multidrug Resistant Mycobacterium tuberculosis

ACS central science, 2020-06, Vol.6 (6), p.833-835

Herzon, Seth B

2020

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Structure elucidation of colibactin and its DNA cross-links

A Method for the Selective Hydrogenation of Alkenyl Halides to Alkyl Halides

Non-classical selectivities in the reduction of alkenes by cobalt-mediated hydrogen atom transfer

On the Abundance and Stability of Diazo-Containing Secondary Metabolites: Enantioselective Synthesis of (−)-Nenestatin A

A modular and enantioselective synthesis of the pleuromutilin antibiotics

Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway

Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective

Synthesis of Ketones and Esters from Heteroatom-Functionalized Alkenes by Cobalt-Mediated Hydrogen Atom Transfer

Development of a Modular Synthetic Route to (+)-Pleuromutilin, (+)-12-epi-Mutilins, and Related Structures

Metric-Based Analysis of Convergence in Complex Molecule Synthesis

Depurination of Colibactin-Derived Interstrand Cross-Links

A Mechanistic Model for Colibactin-Induced Genotoxicity

Temporal separation of catalytic activities allows anti-Markovnikov reductive functionalization of terminal alkynes

Regioselective Reductive Hydration of Alkynes To Form Branched or Linear Alcohols

A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials

Synthesis of 1,3-Amino Alcohols, 1,3-Diols, Amines, and Carboxylic Acids from Terminal Alkynes

Broad-Spectrum Catalysts for the Ambient Temperature Anti-Markovnikov Hydration of Alkynes

Characterization of Natural Colibactin–Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening

Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A

Intermolecular Hydropyridylation of Unactivated Alkenes

Synthesis and reactivity of precolibactin 886

Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis

Development of an Enantioselective Synthesis of (−)-Euonyminol

The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumors

New Leads for the Treatment of Multidrug Resistant Mycobacterium tuberculosis

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