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Hunting coronavirus by transmission electron microscopy – a guide to SARS‐CoV‐2‐associated ultrastructural pathology in COVID‐19 tissues

Histopathology, 2021-02, Vol.78 (3), p.358-370

2021

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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

Human molecular genetics, 2011-11, Vol.20 (21), p.4209-4223

2011

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High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain

PloS one, 2012-05, Vol.7 (5), p.e36581-e36581

2012

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No dopamine cell loss or changes in cytoskeleton function in transgenic mice expressing physiological levels of wild type or G2019S mutant LRRK2 and in human fibroblasts

PloS one, 2015-04, Vol.10 (4), p.e0118947-e0118947

2015

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LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

Human molecular genetics, 2011-11, Vol.20 (21), p.4209-4223

2011

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Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP x Tau Transgenic Mice

The American journal of pathology, 2007-12, Vol.171 (6), p.2012-2020

2007

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Cystatin C modulates cerebral β-amyloidosis

Nature genetics, 2007-12, Vol.39 (12), p.1437-1439

2007

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Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis

Nature neuroscience, 2004-09, Vol.7 (9), p.954-960

2004

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Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

Journal of medicinal chemistry, 2017-11, Vol.60 (21), p.8945-8962

2017

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Mechanism of Cerebral β-Amyloid Angiopathy: Murine and Cellular Models

Brain pathology (Zurich, Switzerland), 2006-01, Vol.16 (1), p.40-54

2006

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Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy

The Journal of neuroscience, 2001-03, Vol.21 (5), p.1619-1627

2001

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Extracellular amyloid formation and associated pathology in neural grafts

Nature neuroscience, 2003-04, Vol.6 (4), p.370-377

2003

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E22Q-Mutant Aβ Peptide (AβDutch) Increases Vascular but Reduces Parenchymal Aβ Deposition

The American journal of pathology, 2009-03, Vol.174 (3), p.722-726

2009

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Independent Effects of Intra- and Extracellular Aβ on Learning-Related Gene Expression

The American journal of pathology, 2009-07, Vol.175 (1), p.271-282

2009

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Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice

The American journal of pathology, 2007-12, Vol.171 (6), p.2012-2020

2007

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Expression and function of the LIM homeodomain protein Apterous during embryonic brain development of Drosophila

Development genes and evolution, 2001-12, Vol.211 (11), p.545-554

2001

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BACE1 and Mutated Presenilin-1 Differently Modulate Aβ40 and Aβ42 Levels and Cerebral Amyloidosis in APPDutch Transgenic Mice

Neuro-degenerative diseases, 2007-06, Vol.4 (2-3), p.127-135

2007

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No Dopamine Cell Loss or Changes in Cytoskeleton Function in Transgenic Mice Expressing Physiological Levels of Wild Type or G2019S Mutant LRRK2 and in Human Fibroblasts: e0118947

PloS one, 2015-04, Vol.10 (4)

2015

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P1-036: Genetic modulation of vascular amyloid in APPDutch mice

Alzheimer's & dementia, 2006-07, Vol.2 (3), p.S104-S105

2006

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Cystatin C modulates cerebral b-amyloidosis

Nature genetics, 2007-12, Vol.39 (12), p.1437-1439

2007

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Cystatin C modulates cerebral [beta]-amyloidosis

Nature genetics, 2007-12, Vol.39 (12), p.1437-1439

2007

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BACE1 and Mutated Presenilin-1 Differently Modulate A[beta]40 and A[beta]42 Levels and Cerebral Amyloidosis in APPDutch Transgenic Mice

Neuro-degenerative diseases, 2007-06, Vol.4 (2-3), p.127

2007

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BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice

Neuro-degenerative diseases, 2007, Vol.4 (2-3), p.127-135

2007

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E22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition

The American journal of pathology, 2009-03, Vol.174 (3), p.722

2009

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P1-072: Transgenic mouse models of familial British and Danish dementias

Alzheimer's & dementia, 2006-07, Vol.2 (3), p.S116-S116

2006

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Hunting coronavirus by transmission electron microscopy – a guide to SARS‐CoV‐2‐associated ultrastructural pathology in COVID‐19 tissues

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain

No dopamine cell loss or changes in cytoskeleton function in transgenic mice expressing physiological levels of wild type or G2019S mutant LRRK2 and in human fibroblasts

LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice

Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP x Tau Transgenic Mice

Cystatin C modulates cerebral β-amyloidosis

Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis

Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

Mechanism of Cerebral β-Amyloid Angiopathy: Murine and Cellular Models

Spontaneous Hemorrhagic Stroke in a Mouse Model of Cerebral Amyloid Angiopathy

Extracellular amyloid formation and associated pathology in neural grafts

E22Q-Mutant Aβ Peptide (AβDutch) Increases Vascular but Reduces Parenchymal Aβ Deposition

Independent Effects of Intra- and Extracellular Aβ on Learning-Related Gene Expression

Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice

Expression and function of the LIM homeodomain protein Apterous during embryonic brain development of Drosophila

BACE1 and Mutated Presenilin-1 Differently Modulate Aβ40 and Aβ42 Levels and Cerebral Amyloidosis in APPDutch Transgenic Mice

No Dopamine Cell Loss or Changes in Cytoskeleton Function in Transgenic Mice Expressing Physiological Levels of Wild Type or G2019S Mutant LRRK2 and in Human Fibroblasts: e0118947

P1-036: Genetic modulation of vascular amyloid in APPDutch mice

Cystatin C modulates cerebral b-amyloidosis

Cystatin C modulates cerebral [beta]-amyloidosis

BACE1 and Mutated Presenilin-1 Differently Modulate A[beta]40 and A[beta]42 Levels and Cerebral Amyloidosis in APPDutch Transgenic Mice

BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice

E22Q-mutant Abeta peptide (AbetaDutch) increases vascular but reduces parenchymal Abeta deposition

P1-072: Transgenic mouse models of familial British and Danish dementias

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