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Structure of puromycin-sensitive aminopeptidase and polyglutamine binding

PloS one, 2023-07, Vol.18 (7), p.e0287086-e0287086

2023

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Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3

PloS one, 2023-05, Vol.18 (5), p.e0285964-e0285964

2023

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Expression of Neprilysin in Skeletal Muscle Reduces Amyloid Burden in a Transgenic Mouse Model of Alzheimer Disease

Molecular therapy, 2009-08, Vol.17 (8), p.1381-1386

2009

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Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice

The Journal of neuroscience, 2003-03, Vol.23 (6), p.1992-1996

2003

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Amyloid-β Peptide Levels in Brain Are Inversely Correlated with Insulysin Activity Levels in vivo

Proceedings of the National Academy of Sciences - PNAS, 2003-05, Vol.100 (10), p.6221-6226

2003

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An Extended Polyanion Activation Surface in Insulin Degrading Enzyme

PloS one, 2015-07, Vol.10 (7), p.e0133114

2015

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Circulating neprilysin clears brain amyloid

Molecular and cellular neuroscience, 2010-10, Vol.45 (2), p.101-107

2010

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Aerosol capture and coronavirus spike protein deactivation by enzyme functionalized antiviral membranes

Communications materials, 2022-12, Vol.3 (1), p.1-15, Article 34

2022

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Neuropeptide Y Fragments Derived from Neprilysin Processing Are Neuroprotective in a Transgenic Model of Alzheimer's Disease

The Journal of neuroscience, 2009-01, Vol.29 (4), p.1115-1125

2009

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The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells

PloS one, 2015-07, Vol.10 (7), p.e0133263-e0133263

2015

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Active site mutations change the cleavage specificity of neprilysin

PloS one, 2012-02, Vol.7 (2), p.e32343

2012

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Identification of the allosteric regulatory site of insulysin

PloS one, 2011-06, Vol.6 (6), p.e20864-e20864

2011

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Peripherally expressed neprilysin reduces brain amyloid burden: A novel approach for treating Alzheimer's disease

Journal of neuroscience research, 2009-05, Vol.87 (6), p.1462-1473

2009

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A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties

PloS one, 2010-03, Vol.5 (3), p.e9719-e9719

2010

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Decreased Catalytic Activity of the Insulin-degrading Enzyme in Chromosome 10-Linked Alzheimer Disease Families

The Journal of biological chemistry, 2007-03, Vol.282 (11), p.7825-7832

2007

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Intraneuronal Amylin Deposition, Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats

Journal of Alzheimer's disease, 2016-05, Vol.53 (1), p.259

2016

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Toxoplasma gondii Toxolysin 4 Contributes to Efficient Parasite Egress from Host Cells

mSphere, 2021-06, Vol.6 (3), p.e0044421-e0044421

2021

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Two new proteases in the MHC class I processing pathway

Nature immunology, 2000-11, Vol.1 (5), p.413-418

2000

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Neprilysin Null Mice Develop Exaggerated Pulmonary Vascular Remodeling in Response to Chronic Hypoxia

The American journal of pathology, 2009-03, Vol.174 (3), p.782-796

2009

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REST/NRSF-Interacting LIM Domain Protein, a Putative Nuclear Translocation Receptor

Molecular and Cellular Biology, 2003-12, Vol.23 (24), p.9025-9031

2003

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Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation

PloS one, 2012-10, Vol.7 (10), p.e46790-e46790

2012

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Insulin-degrading enzyme is not secreted from cultured cells

Scientific reports, 2018-02, Vol.8 (1), p.2335-8, Article 2335

2018

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ATP Effects on Insulin-degrading Enzyme Are Mediated Primarily through Its Triphosphate Moiety

The Journal of biological chemistry, 2004-12, Vol.279 (52), p.54216-54220

2004

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Aminopeptidases do not directly degrade tau protein

Molecular neurodegeneration, 2010-11, Vol.5 (1), p.48-48

2010

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Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice

Arteriosclerosis, thrombosis, and vascular biology, 2018-01, Vol.38 (1), p.154

2018

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Structure of puromycin-sensitive aminopeptidase and polyglutamine binding

Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3

Expression of Neprilysin in Skeletal Muscle Reduces Amyloid Burden in a Transgenic Mouse Model of Alzheimer Disease

Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice

Amyloid-β Peptide Levels in Brain Are Inversely Correlated with Insulysin Activity Levels in vivo

An Extended Polyanion Activation Surface in Insulin Degrading Enzyme

Circulating neprilysin clears brain amyloid

Aerosol capture and coronavirus spike protein deactivation by enzyme functionalized antiviral membranes

Neuropeptide Y Fragments Derived from Neprilysin Processing Are Neuroprotective in a Transgenic Model of Alzheimer's Disease

The Mitochondrial Peptidase Pitrilysin Degrades Islet Amyloid Polypeptide in Beta-Cells

Active site mutations change the cleavage specificity of neprilysin

Identification of the allosteric regulatory site of insulysin

Peripherally expressed neprilysin reduces brain amyloid burden: A novel approach for treating Alzheimer's disease

A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties

Decreased Catalytic Activity of the Insulin-degrading Enzyme in Chromosome 10-Linked Alzheimer Disease Families

Intraneuronal Amylin Deposition, Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats

Toxoplasma gondii Toxolysin 4 Contributes to Efficient Parasite Egress from Host Cells

Two new proteases in the MHC class I processing pathway

Neprilysin Null Mice Develop Exaggerated Pulmonary Vascular Remodeling in Response to Chronic Hypoxia

REST/NRSF-Interacting LIM Domain Protein, a Putative Nuclear Translocation Receptor

Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation

Insulin-degrading enzyme is not secreted from cultured cells

ATP Effects on Insulin-degrading Enzyme Are Mediated Primarily through Its Triphosphate Moiety

Aminopeptidases do not directly degrade tau protein

Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice

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