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Asleep blood pressure: significant prognostic marker of vascular risk and therapeutic target for prevention

European heart journal, 2018-12, Vol.39 (47), p.4159-4171

2018

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Circadian mechanisms of 24-hour blood pressure regulation and patterning

Sleep medicine reviews, 2017-06, Vol.33, p.4-16

2017

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Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial

European heart journal, 2020-12, Vol.41 (48), p.4565-4576

2020

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Decreasing Sleep-Time Blood Pressure Determined by Ambulatory Monitoring Reduces Cardiovascular Risk

Journal of the American College of Cardiology, 2011-09, Vol.58 (11), p.1165-1173

2011

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Dosing time optimization of antihypertensive medications by including the circadian rhythm in pharmacokinetic-pharmacodynamic models

PLoS computational biology, 2022-11, Vol.18 (11), p.e1010711

2022

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Treatment of sleep-disordered breathing, alone, is insufficient for proper management of sleep-time hypertension

European heart journal, 2019-10, Vol.40 (38), p.3208-3208

Hermida, Ramón C

2019

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Sleep-time ambulatory blood pressure as a prognostic marker of vascular and other risks and therapeutic target for prevention by hypertension chronotherapy: Rationale and design of the Hygia Project

Chronobiology international, 2016-01, Vol.33 (7), p.906-936

Hermida, Ramón C

2016

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Extent of asleep blood pressure reduction by hypertension medications is ingestion-time dependent: Systematic review and meta-analysis of published human trials

Sleep medicine reviews, 2021-10, Vol.59, p.101454-101454, Article 101454

2021

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Ingestion-time differences in the pharmacodynamics of hypertension medications: Systematic review of human chronopharmacology trials

Advanced drug delivery reviews, 2021-03, Vol.170, p.200-213

2021

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Circadian variation of blood pressure: The basis for the chronotherapy of hypertension

Advanced drug delivery reviews, 2007-08, Vol.59 (9), p.904-922

2007

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INFLUENCE OF CIRCADIAN TIME OF HYPERTENSION TREATMENT ON CARDIOVASCULAR RISK: RESULTS OF THE MAPEC STUDY

Chronobiology international, 2010-10, Vol.27 (8), p.1629-1651

2010

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Circadian rhythms and cardiovascular health

Sleep medicine reviews, 2012-04, Vol.16 (2), p.151-166

2012

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Chronotherapy With Low-Dose Aspirin for Prevention of Complications in Pregnancy

Chronobiology international, 2013-03, Vol.30 (1-2), p.260-279

2013

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Chronotherapy Improves Blood Pressure Control and Reverts the Nondipper Pattern in Patients With Resistant Hypertension

Hypertension (Dallas, Tex. 1979), 2008-01, Vol.51 (1), p.69-76

2008

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Bedtime Dosing of Antihypertensive Medications Reduces Cardiovascular Risk in CKD

Journal of the American Society of Nephrology, 2011-12, Vol.22 (12), p.2313-2321

2011

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Commentary on Bowles and Shea: Further perspectives and clinical implications of ingestion-time differences in the efficacy of blood pressure-lowering medications

Sleep medicine reviews, 2021-10, Vol.59, p.101540-101540, Article 101540

2021

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Impact of hypertension treatment-time on cardiovascular outcomes: erroneous trial selection leading to suspect findings

Journal of hypertension, 2024-01, Vol.42 (1), p.190-191

2024

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Blunted Sleep-Time Relative Blood Pressure Decline Increases Cardiovascular Risk Independent of Blood Pressure Level-The "Normotensive Non-dipper" Paradox

Chronobiology international, 2013-03, Vol.30 (1-2), p.87-98

2013

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Systematic review and quality evaluation of published human ingestion-time trials of blood pressure-lowering medications and their combinations

Chronobiology international, 2021-10, Vol.38 (10), p.1460-1476

2021

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Ingestion-time differences in the pharmacodynamics of dual-combination hypertension therapies: Systematic review and meta-analysis of published human trials

Chronobiology international, 2022-04, Vol.39 (4), p.493-512

2022

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Lowering Nighttime Blood Pressure With Bedtime Dosing of Antihypertensive Medications: Controversies in Hypertension-Pro Side of the Argument

Hypertension (Dallas, Tex. 1979), 2021-09, Vol.78 (3), p.879-893

2021

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Improved reduction of cardiovascular risk by bedtime ingestion of ARB and ACEI medication class therapies

European heart journal, 2020-04, Vol.41 (16), p.1602-1603

2020

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Critical appraisal of recent translational chronopharmacology and chronotherapeutic reviews, meta-analyses, and pragmatic patient trials discloses significant deficiencies of design and conduct and suspect findings

Chronobiology international, 2023-08, Vol.40 (8), p.1146-1167

2023

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Ingestion-time - relative to circadian rhythms - differences in the pharmacokinetics and pharmacodynamics of hypertension medications

Expert opinion on drug metabolism & toxicology, 2020-12, Vol.16 (12), p.1159-1173

2020

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Comparing the design of the primary-care based Hygia Chronotherapy Trial and the Internet-Based TIME Study

European heart journal, 2020-04, Vol.41 (16), p.1608-1608

2020

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Asleep blood pressure: significant prognostic marker of vascular risk and therapeutic target for prevention

Circadian mechanisms of 24-hour blood pressure regulation and patterning

Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial

Decreasing Sleep-Time Blood Pressure Determined by Ambulatory Monitoring Reduces Cardiovascular Risk

Dosing time optimization of antihypertensive medications by including the circadian rhythm in pharmacokinetic-pharmacodynamic models

Treatment of sleep-disordered breathing, alone, is insufficient for proper management of sleep-time hypertension

Sleep-time ambulatory blood pressure as a prognostic marker of vascular and other risks and therapeutic target for prevention by hypertension chronotherapy: Rationale and design of the Hygia Project

Extent of asleep blood pressure reduction by hypertension medications is ingestion-time dependent: Systematic review and meta-analysis of published human trials

Ingestion-time differences in the pharmacodynamics of hypertension medications: Systematic review of human chronopharmacology trials

Circadian variation of blood pressure: The basis for the chronotherapy of hypertension

INFLUENCE OF CIRCADIAN TIME OF HYPERTENSION TREATMENT ON CARDIOVASCULAR RISK: RESULTS OF THE MAPEC STUDY

Circadian rhythms and cardiovascular health

Chronotherapy With Low-Dose Aspirin for Prevention of Complications in Pregnancy

Chronotherapy Improves Blood Pressure Control and Reverts the Nondipper Pattern in Patients With Resistant Hypertension

Bedtime Dosing of Antihypertensive Medications Reduces Cardiovascular Risk in CKD

Commentary on Bowles and Shea: Further perspectives and clinical implications of ingestion-time differences in the efficacy of blood pressure-lowering medications

Impact of hypertension treatment-time on cardiovascular outcomes: erroneous trial selection leading to suspect findings

Blunted Sleep-Time Relative Blood Pressure Decline Increases Cardiovascular Risk Independent of Blood Pressure Level-The "Normotensive Non-dipper" Paradox

Systematic review and quality evaluation of published human ingestion-time trials of blood pressure-lowering medications and their combinations

Ingestion-time differences in the pharmacodynamics of dual-combination hypertension therapies: Systematic review and meta-analysis of published human trials

Lowering Nighttime Blood Pressure With Bedtime Dosing of Antihypertensive Medications: Controversies in Hypertension-Pro Side of the Argument

Improved reduction of cardiovascular risk by bedtime ingestion of ARB and ACEI medication class therapies

Critical appraisal of recent translational chronopharmacology and chronotherapeutic reviews, meta-analyses, and pragmatic patient trials discloses significant deficiencies of design and conduct and suspect findings

Ingestion-time - relative to circadian rhythms - differences in the pharmacokinetics and pharmacodynamics of hypertension medications

Comparing the design of the primary-care based Hygia Chronotherapy Trial and the Internet-Based TIME Study

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