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To "Z" or not to "Z": Z-RNA, self-recognition, and the MDA5 helicase

PLoS genetics, 2021-05, Vol.17 (5), p.e1009513-e1009513

2021

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Z-DNA and Z-RNA in human disease

Communications biology, 2019-01, Vol.2 (1), p.7-7, Article 7

Herbert, Alan

2019

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The Intransitive Logic of Directed Cycles and Flipons Enhances the Evolution of Molecular Computers by Augmenting the Kolmogorov Complexity of Genomes

International journal of molecular sciences, 2023-11, Vol.24 (22), p.16482

Herbert, Alan

2023

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The Simple Biology of Flipons and Condensates Enhances the Evolution of Complexity

Molecules (Basel, Switzerland), 2021-08, Vol.26 (16), p.4881

Herbert, Alan

2021

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Flipons: The Discovery of Z-DNA and Soft-Wired Genomes

Herbert, Alan

1, 2024

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The ancient Z-DNA and Z-RNA specific Zα fold has evolved modern roles in immunity and transcription through the natural selection of flipons

Royal Society open science, 2024-06, Vol.11 (6)

Herbert, Alan

2024

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ALU non-B-DNA conformations, flipons, binary codes and evolution

Royal Society open science, 2020-06, Vol.7 (6), p.200222-200222

Herbert, Alan

2020

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Contextual Cell Death in Adaptive Immunity: Selecting a Winning Response

Frontiers in immunology, 2019-12, Vol.10, p.2898-2898

Herbert, Alan

2019

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Complement controls the immune synapse and tumors control complement

Journal for immunotherapy of cancer, 2020-12, Vol.8 (2), p.e001712

Herbert, Alan

2020

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Vaiṣṇava Concepts of God: Philosophical Perspectives

1, 2024

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Z-RNA and the Flipside of the SARS Nsp13 Helicase: Is There a Role for Flipons in Coronavirus-Induced Pathology?

Frontiers in immunology, 2022-06, Vol.13, p.912717-912717

2022

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ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Nature (London), 2022-06, Vol.606 (7914), p.594

2022

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Conserved microRNAs and Flipons Shape Gene Expression during Development by Altering Promoter Conformations

International journal of molecular sciences, 2023-03, Vol.24 (5), p.4884

2023

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Mono a Mano: ZBP1's Love-Hate Relationship with the Kissing Virus

International journal of molecular sciences, 2022-03, Vol.23 (6), p.3079

2022

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Z-DNA enhances immunotherapy by triggering death of inflammatory cancer-associated fibroblasts

Journal for immunotherapy of cancer, 2022-11, Vol.10 (11), p.e005704

2022

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Flipons and small RNAs accentuate the asymmetries of pervasive transcription by the reset and sequence-specific microcoding of promoter conformation

The Journal of biological chemistry, 2023-09, Vol.299 (9), p.105140-105140, Article 105140

Herbert, Alan

2023

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ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing

Cell reports (Cambridge), 2023-07, Vol.42 (7), p.112733-112733, Article 112733

2023

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Mendelian disease caused by variants affecting recognition of Z-DNA and Z-RNA by the Zα domain of the double-stranded RNA editing enzyme ADAR

European journal of human genetics : EJHG, 2020-01, Vol.28 (1), p.114-117

Herbert, Alan

2020

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Nucleosomes and flipons exchange energy to alter chromatin conformation, the readout of genomic information, and cell fate

BioEssays, 2022-12, Vol.44 (12), p.e2200166-n/a

Herbert, Alan

2022

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A Genetic Instruction Code Based on DNA Conformation

Trends in genetics, 2019-12, Vol.35 (12), p.887-890

Herbert, Alan

2019

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Osteogenesis imperfecta type 10 and the cellular scaffolds underlying common immunological diseases

Genes and immunity, 2024-05

Herbert, Alan

2024

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Simple Repeats as Building Blocks for Genetic Computers

Trends in genetics, 2020-10, Vol.36 (10), p.739-750

Herbert, Alan

2020

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A genome-wide association study of hypertension and blood pressure in African Americans

PLoS genetics, 2009-07, Vol.5 (7), p.e1000564-e1000564

2009

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Z-DNA and Z-RNA: Methods-Past and Future

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2651, p.295

Herbert, Alan

2023

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Unsupervised domain adaptation methods for cross-species transfer of regulatory code signals

Frontiers in big data, 2023-03, Vol.6, p.1140663-1140663

2023

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To "Z" or not to "Z": Z-RNA, self-recognition, and the MDA5 helicase

Z-DNA and Z-RNA in human disease

The Intransitive Logic of Directed Cycles and Flipons Enhances the Evolution of Molecular Computers by Augmenting the Kolmogorov Complexity of Genomes

The Simple Biology of Flipons and Condensates Enhances the Evolution of Complexity

Flipons: The Discovery of Z-DNA and Soft-Wired Genomes

The ancient Z-DNA and Z-RNA specific Zα fold has evolved modern roles in immunity and transcription through the natural selection of flipons

ALU non-B-DNA conformations, flipons, binary codes and evolution

Contextual Cell Death in Adaptive Immunity: Selecting a Winning Response

Complement controls the immune synapse and tumors control complement

Vaiṣṇava Concepts of God: Philosophical Perspectives

Z-RNA and the Flipside of the SARS Nsp13 Helicase: Is There a Role for Flipons in Coronavirus-Induced Pathology?

ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis

Conserved microRNAs and Flipons Shape Gene Expression during Development by Altering Promoter Conformations

Mono a Mano: ZBP1's Love-Hate Relationship with the Kissing Virus

Z-DNA enhances immunotherapy by triggering death of inflammatory cancer-associated fibroblasts

Flipons and small RNAs accentuate the asymmetries of pervasive transcription by the reset and sequence-specific microcoding of promoter conformation

ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing

Mendelian disease caused by variants affecting recognition of Z-DNA and Z-RNA by the Zα domain of the double-stranded RNA editing enzyme ADAR

Nucleosomes and flipons exchange energy to alter chromatin conformation, the readout of genomic information, and cell fate

A Genetic Instruction Code Based on DNA Conformation

Osteogenesis imperfecta type 10 and the cellular scaffolds underlying common immunological diseases

Simple Repeats as Building Blocks for Genetic Computers

A genome-wide association study of hypertension and blood pressure in African Americans

Z-DNA and Z-RNA: Methods-Past and Future

Unsupervised domain adaptation methods for cross-species transfer of regulatory code signals

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