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Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy

British journal of cancer, 2020-09, Vol.123 (5), p.694-697

2020

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Effect of the COVID-19 pandemic on cancer treatment and research

The Lancet. Haematology, 2020-06, Vol.7 (6), p.e432-e435

2020

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CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Biochemical journal, 2019-05, Vol.476 (9), p.1335-1357

2019

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Clinicopathological and molecular predictors of [18F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial

European journal of nuclear medicine and molecular imaging, 2024-07, Vol.51 (9), p.2733-2743

2024

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Role of decentralized clinical trials in cancer drug development: Results from a survey of oncologists and patients

Digital health, 2022, Vol.8, p.20552076221099997-20552076221099997

2022

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A phase I, dose-escalation study of the multitargeted receptor tyrosine kinase inhibitor, golvatinib, in patients with advanced solid tumors

Clinical cancer research, 2014-12, Vol.20 (24), p.6284-6294

2014

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Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer

The New England journal of medicine, 2015-02, Vol.372 (7), p.621-630

2015

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Targeting virulence not viability in the search for future antibacterials

British journal of clinical pharmacology, 2015-02, Vol.79 (2), p.208-215

2015

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A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment

Angewandte Chemie International Edition, 2020-06, Vol.59 (25), p.10129-10135

International ed. in English, 2020

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Detection of Bacterial Membrane Vesicles by NOD-Like Receptors

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1005

2021

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The economic burden of metastatic breast cancer in Spain

European journal of hospital pharmacy. Science and practice, 2020-01, Vol.27 (1), p.19-24

2020

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Bioinformatics Tools and Resources for Analyzing Protein Structures

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1549, p.209

2017

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Phylogenetic Classification and Functional Review of Autotransporters

Frontiers in immunology, 2022-07, Vol.13, p.921272-921272

2022

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Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

Nature communications, 2019-04, Vol.10 (1), p.1967-1967, Article 1967

2019

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A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

Scientific reports, 2021-01, Vol.11 (1), p.1569-1569, Article 1569

2021

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Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents

Molecules (Basel, Switzerland), 2016-07, Vol.21 (7), p.811

2016

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A Phase II Prospective, Randomized, Double‐Blind, Placebo‐Controlled and Multicenter Clinical Trial to Assess the Safety of 0.005% Estriol Vaginal Gel in Hormone Receptor‐Positive Postmenopausal Women with Early Stage Breast Cancer in Treatment with Aromatase Inhibitor in the Adjuvant Setting

The oncologist (Dayton, Ohio), 2020-12, Vol.25 (12), p.e1846-1854

2020

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antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (1), p.457-462

2014

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Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function

Nature communications, 2023-03, Vol.14 (1), p.1163-1163, Article 1163

2023

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Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens

Antioxidants & redox signaling, 2018-09, Vol.29 (7), p.653-666

2018

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Rapid Elaboration of Fragments into Leads by X‑ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX)

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.6863-6875

2020

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The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance

The Journal of biological chemistry, 2019-11, Vol.294 (44), p.15876-15888

2019

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Healthy volunteers in first‐in‐human oncology drug development for small molecules

British journal of clinical pharmacology, 2022-02, Vol.88 (4), p.1773-1784

2022

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Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes

Scientific reports, 2022-07, Vol.12 (1), p.11231-11231, Article 11231

2022

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The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors

Molecules (Basel, Switzerland), 2019-10, Vol.24 (20), p.3756

2019

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Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy

Effect of the COVID-19 pandemic on cancer treatment and research

CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants

Clinicopathological and molecular predictors of [18F]FDG-PET disease detection in HER2-positive early breast cancer: RESPONSE, a substudy of the randomized PHERGain trial

Role of decentralized clinical trials in cancer drug development: Results from a survey of oncologists and patients

A phase I, dose-escalation study of the multitargeted receptor tyrosine kinase inhibitor, golvatinib, in patients with advanced solid tumors

Lenvatinib versus Placebo in Radioiodine-Refractory Thyroid Cancer

Targeting virulence not viability in the search for future antibacterials

A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment

Detection of Bacterial Membrane Vesicles by NOD-Like Receptors

The economic burden of metastatic breast cancer in Spain

Bioinformatics Tools and Resources for Analyzing Protein Structures

Phylogenetic Classification and Functional Review of Autotransporters

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents

A Phase II Prospective, Randomized, Double‐Blind, Placebo‐Controlled and Multicenter Clinical Trial to Assess the Safety of 0.005% Estriol Vaginal Gel in Hormone Receptor‐Positive Postmenopausal Women with Early Stage Breast Cancer in Treatment with Aromatase Inhibitor in the Adjuvant Setting

antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping

Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function

Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens

Rapid Elaboration of Fragments into Leads by X‑ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX)

The Scs disulfide reductase system cooperates with the metallochaperone CueP in Salmonella copper resistance

Healthy volunteers in first‐in‐human oncology drug development for small molecules

Methyl probes in proteins for determining ligand binding mode in weak protein–ligand complexes

The Fragment-Based Development of a Benzofuran Hit as a New Class of Escherichia coli DsbA Inhibitors

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