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Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

Cell, 2018-11, Vol.175 (6), p.1665-1678.e18

2018

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WNT Signaling as a Therapeutic Target for Glioblastoma

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8428

2021

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Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities

Nature communications, 2020-07, Vol.11 (1), p.3288-3288, Article 3288

2020

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Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

Genome Biology, 2020-08, Vol.21 (1), p.216-17, Article 216

2020

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Potent effect of the MDM2 inhibitor AMG232 on suppression of glioblastoma stem cells

Cell death & disease, 2018-07, Vol.9 (8), p.792-12, Article 792

2018

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Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer

Scientific reports, 2020-05, Vol.10 (1), p.8096-8096, Article 8096

2020

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Cellular thermal shift analysis for interrogation of CRISPR-assisted proteomic changes

BioTechniques, 2020-04, Vol.68 (4), p.180-184

2020

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XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (43), p.15532-15537

2014

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The Protein Neddylation Inhibitor MLN4924 Suppresses Patient-Derived Glioblastoma Cells via Inhibition of ERK and AKT Signaling

Cancers, 2019-11, Vol.11 (12), p.1849

2019

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Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers

Genome Biology, 2019-11, Vol.20 (1), p.253-253, Article 253

2019

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High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted Glioblastoma

Cancers, 2021-01, Vol.13 (3), p.372

2021

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Comprehensive pharmacogenomic characterization of gastric cancer

Genome medicine, 2020-02, Vol.12 (1), p.17-12, Article 17

2020

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Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells

Cell cycle (Georgetown, Tex.), 2020-07, Vol.19 (13), p.1590-1601

2020

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cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors

ACS omega, 2020-10, Vol.5 (40), p.25798-25809

2020

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DeepHCS++: Bright-field to fluorescence microscopy image conversion using multi-task learning with adversarial losses for label-free high-content screening

Medical image analysis, 2021-05, Vol.70, p.101995-101995, Article 101995

2021

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p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity

Cell chemical biology, 2016-04, Vol.23 (4), p.517-528

2016

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Automated stitching of microscope images of fluorescence in cells with minimal overlap

Micron (Oxford, England : 1993), 2019-11, Vol.126, p.102718-102718, Article 102718

2019

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Accuracy improvement of quantification information using super-resolution with convolutional neural network for microscopy images

Biomedical signal processing and control, 2020-04, Vol.58, p.101846, Article 101846

2020

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Radiation-inducible miR-770-5p sensitizes tumors to radiation through direct targeting of PDZ-binding kinase

Cell death & disease, 2017-03, Vol.8 (3), p.e2693-e2693

2017

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PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway

Cell cycle (Georgetown, Tex.), 2013-05, Vol.12 (10), p.1521-1535

2013

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DeepHCS: Bright-Field to Fluorescence Microscopy Image Conversion Using Deep Learning for Label-Free High-Content Screening

Medical Image Computing and Computer Assisted Intervention – MICCAI 2018, p.335-343

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Abstract 3123: Preclinical characterization of AMB302/GQ1011, a first-in-class FGFR3 antibody-drug conjugate (ADC) with topoisomerase 1 inhibitor against diverse FGFR3 overexpression or alteration

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.3123-3123

2024

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Abstract 3411: Proof of concept study of next generation drug screening platform for glioma patients

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3411-3411

2023

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Abstract 3410: AVATASCAN®, a pioneer of functional precision medicine in guiding clinical decision-making

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3410-3410

2023

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Abstract 2634: AMB302/GR1017, an antibody-drug conjugate (ADC) with topoisomerase 1 inhibitor shows therapeutic potency in orthotopic glioblastoma PDX and bladder cancer models with FGFR3-TACC3 fusion

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2634-2634

2023

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Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

WNT Signaling as a Therapeutic Target for Glioblastoma

Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

Potent effect of the MDM2 inhibitor AMG232 on suppression of glioblastoma stem cells

Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer

Cellular thermal shift analysis for interrogation of CRISPR-assisted proteomic changes

XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313

The Protein Neddylation Inhibitor MLN4924 Suppresses Patient-Derived Glioblastoma Cells via Inhibition of ERK and AKT Signaling

Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers

High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted Glioblastoma

Comprehensive pharmacogenomic characterization of gastric cancer

Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells

cIRCR201-dPBD, a Novel Pyrrolobenzodiazepine Dimer-Containing Site-Specific Antibody–Drug Conjugate Targeting c‑Met Overexpression Tumors

DeepHCS++: Bright-field to fluorescence microscopy image conversion using multi-task learning with adversarial losses for label-free high-content screening

p97 Composition Changes Caused by Allosteric Inhibition Are Suppressed by an On-Target Mechanism that Increases the Enzyme's ATPase Activity

Automated stitching of microscope images of fluorescence in cells with minimal overlap

Accuracy improvement of quantification information using super-resolution with convolutional neural network for microscopy images

Radiation-inducible miR-770-5p sensitizes tumors to radiation through direct targeting of PDZ-binding kinase

PPARδ promotes oncogenic redirection of TGF-β1 signaling through the activation of the ABCA1-Cav1 pathway

DeepHCS: Bright-Field to Fluorescence Microscopy Image Conversion Using Deep Learning for Label-Free High-Content Screening

Abstract 3123: Preclinical characterization of AMB302/GQ1011, a first-in-class FGFR3 antibody-drug conjugate (ADC) with topoisomerase 1 inhibitor against diverse FGFR3 overexpression or alteration

Abstract 3411: Proof of concept study of next generation drug screening platform for glioma patients

Abstract 3410: AVATASCAN®, a pioneer of functional precision medicine in guiding clinical decision-making

Abstract 2634: AMB302/GR1017, an antibody-drug conjugate (ADC) with topoisomerase 1 inhibitor shows therapeutic potency in orthotopic glioblastoma PDX and bladder cancer models with FGFR3-TACC3 fusion

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