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Pd-Catalyzed Cross-Coupling Reactions Promoted by Biaryl Phosphorinane Ligands

ACS catalysis, 2019-12, Vol.9 (12), p.11691-11708

2019

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Efficient Co-crystal Screening Using Solution-Mediated Phase Transformation

Journal of pharmaceutical sciences, 2007-05, Vol.96 (5), p.990-995

2007

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Synthon Hierarchies in Crystal Forms Composed of Theophylline and Hydroxybenzoic Acids: Cocrystal Screening via Solution-Mediated Phase Transformation

Crystal growth & design, 2014-10, Vol.14 (10), p.5318-5328

2014

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Cocrystals of Caffeine and Hydroxybenzoic Acids Composed of Multiple Supramolecular Heterosynthons: Screening via Solution-Mediated Phase Transformation and Structural Characterization

Crystal growth & design, 2009-04, Vol.9 (4), p.1932-1943

2009

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Pharmaceutical Nano-Cocrystals: Sonochemical Synthesis by Solvent Selection and Use of a Surfactant

Angewandte Chemie (International ed.), 2010-09, Vol.49 (40), p.7284-7288

2010

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Ritonavir Form III: A New Polymorph After 24 Years

Journal of pharmaceutical sciences, 2023-01, Vol.112 (1), p.237-242

2023

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Inhibiting Sublimation of Thymol by Cocrystallization

Journal of pharmaceutical sciences, 2023-01, Vol.112 (1), p.350-353

2023

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Co-Crystals of Caffeine and Hydroxy-2-naphthoic Acids: Unusual Formation of the Carboxylic Acid Dimer in the Presence of a Heterosynthon

Molecular pharmaceutics, 2007-05, Vol.4 (3), p.339-346

2007

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Implications of the Conformationally Flexible, Macrocyclic Structure of the First-Generation, Direct-Acting Anti-Viral Paritaprevir on Its Solid Form Complexity and Chameleonic Behavior

Journal of the American Chemical Society, 2021-10, Vol.143 (42), p.17479-17491

2021

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Pd-Catalyzed Cross-Coupling of Hindered, Electron-Deficient Anilines with Bulky (Hetero)aryl Halides Using Biaryl Phosphorinane Ligands

ACS catalysis, 2020-12, Vol.10 (24), p.15008-15018

2020

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Overcoming Bioavailability Challenges of Dasabuvir and Enabling a Triple-Combination Direct-Acting Antiviral HCV Regimen through a Salt of Very Weak Acid for Oral Delivery

Molecular pharmaceutics, 2022-07, Vol.19 (7), p.2367-2379

2022

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Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate

Journal of medicinal chemistry, 2022-12, Vol.65 (23), p.15893-15934

2022

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Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis

Scientific reports, 2019-06, Vol.9 (1), p.9089-15, Article 9089

2019

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Pharmaceutical Development Challenges in a Beyond Rule of Five Prodrug: Case Study of ABBV-167, Phosphate Prodrug of Venetoclax

Molecular pharmaceutics, 2023-11, Vol.20 (11), p.5811-5826

2023

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Enabling Suzuki-Miyaura coupling of Lewis-basic arylboronic esters with a nonprecious metal catalyst

Chemical science (Cambridge), 2022-11, Vol.13 (43), p.1296-12912

2022

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Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467

Journal of organic chemistry, 2023-11, Vol.88 (22), p.15562-15568

2023

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Scalable Synthesis and Isolation of the Four Stereoisomers of Methyl 1-Amino-3-(4-bromophenyl)cyclopentanecarboxylate, Useful Intermediates for the Synthesis of S1P1 Receptor Agonists

Journal of organic chemistry, 2009-07, Vol.74 (13), p.4886-4889

2009

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Correction to “Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate”

Journal of medicinal chemistry, 2023-04, Vol.66 (8), p.6010-6010

2023

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Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain – A fragment based approach

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1708-1713

2018

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An Intramolecular OH···π(arene) Interaction in a BINOL–Phenazine Cocrystal with a “Free” N‑Atom

Crystal growth & design, 2018-07, Vol.18 (7), p.3890-3895

2018

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Supramolecular Complexes of Sulfadiazine and Pyridines: Reconfigurable Exteriors and Chameleon-like Behavior of Tautomers at the Co-Crystal–Salt Boundary

Crystal growth & design, 2013-01, Vol.13 (1), p.393-403

2013

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A cascade reaction sequence en route to 7-substituted 2-aminopyrrolo[1,2- a]pyrimidine-4,6-diones and the corresponding acrylic acid derivatives

Tetrahedron letters, 2007-10, Vol.48 (41), p.7395-7398

2007

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Effects of Substitution on 9-(3-Bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a Dihydropyridine ATP-Sensitive Potassium Channel Opener

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6869-6887

2006

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Synthesis and evaluation of 2′-dihalo ribonucleotide prodrugs with activity against hepatitis C virus

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115208, Article 115208

2020

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Reducing a cocrystal to nanoscale dimensions enables retention of physical crystal integrity upon dehydration

CrystEngComm, 2017, Vol.19 (27), p.3723-3726

2017

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Pd-Catalyzed Cross-Coupling Reactions Promoted by Biaryl Phosphorinane Ligands

Efficient Co-crystal Screening Using Solution-Mediated Phase Transformation

Synthon Hierarchies in Crystal Forms Composed of Theophylline and Hydroxybenzoic Acids: Cocrystal Screening via Solution-Mediated Phase Transformation

Cocrystals of Caffeine and Hydroxybenzoic Acids Composed of Multiple Supramolecular Heterosynthons: Screening via Solution-Mediated Phase Transformation and Structural Characterization

Pharmaceutical Nano-Cocrystals: Sonochemical Synthesis by Solvent Selection and Use of a Surfactant

Ritonavir Form III: A New Polymorph After 24 Years

Inhibiting Sublimation of Thymol by Cocrystallization

Co-Crystals of Caffeine and Hydroxy-2-naphthoic Acids: Unusual Formation of the Carboxylic Acid Dimer in the Presence of a Heterosynthon

Implications of the Conformationally Flexible, Macrocyclic Structure of the First-Generation, Direct-Acting Anti-Viral Paritaprevir on Its Solid Form Complexity and Chameleonic Behavior

Pd-Catalyzed Cross-Coupling of Hindered, Electron-Deficient Anilines with Bulky (Hetero)aryl Halides Using Biaryl Phosphorinane Ligands

Overcoming Bioavailability Challenges of Dasabuvir and Enabling a Triple-Combination Direct-Acting Antiviral HCV Regimen through a Salt of Very Weak Acid for Oral Delivery

Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate

Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis

Pharmaceutical Development Challenges in a Beyond Rule of Five Prodrug: Case Study of ABBV-167, Phosphate Prodrug of Venetoclax

Enabling Suzuki-Miyaura coupling of Lewis-basic arylboronic esters with a nonprecious metal catalyst

Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467

Scalable Synthesis and Isolation of the Four Stereoisomers of Methyl 1-Amino-3-(4-bromophenyl)cyclopentanecarboxylate, Useful Intermediates for the Synthesis of S1P1 Receptor Agonists

Correction to “Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate”

Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain – A fragment based approach

An Intramolecular OH···π(arene) Interaction in a BINOL–Phenazine Cocrystal with a “Free” N‑Atom

Supramolecular Complexes of Sulfadiazine and Pyridines: Reconfigurable Exteriors and Chameleon-like Behavior of Tautomers at the Co-Crystal–Salt Boundary

A cascade reaction sequence en route to 7-substituted 2-aminopyrrolo[1,2- a]pyrimidine-4,6-diones and the corresponding acrylic acid derivatives

Effects of Substitution on 9-(3-Bromo-4-fluorophenyl)-5,9-dihydro-3H,4H-2,6-dioxa-4- azacyclopenta[b]naphthalene-1,8-dione, a Dihydropyridine ATP-Sensitive Potassium Channel Opener

Synthesis and evaluation of 2′-dihalo ribonucleotide prodrugs with activity against hepatitis C virus

Reducing a cocrystal to nanoscale dimensions enables retention of physical crystal integrity upon dehydration

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