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Converting peptides into drugs targeting intracellular protein–protein interactions

Drug discovery today, 2021-06, Vol.26 (6), p.1521-1531

2021

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Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics

Oncogene, 2020-02, Vol.39 (6), p.1167-1184

2020

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Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome

Nature communications, 2023-07, Vol.14 (1), p.3940-3940, Article 3940

2023

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Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

Blood, 2011-12, Vol.118 (25), p.6709-6717

2011

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Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications

International journal of molecular sciences, 2023-03, Vol.24 (6), p.5893

2023

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Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

The Journal of biological chemistry, 2011-10, Vol.286 (42), p.36932-36943

2011

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Investigations into the membrane activity of arenicin antimicrobial peptide AA139

Biochimica et biophysica acta. General subjects, 2022-08, Vol.1866 (8), p.130156-130156, Article 130156

2022

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Synthesis, Structure, and Activity of the Antifungal Plant Defensin PvD1

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9391-9402

2020

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Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells

ACS chemical biology, 2021-02, Vol.16 (2), p.414-428

2021

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Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

Scientific reports, 2015-08, Vol.5 (1), p.12974-12974, Article 12974

2015

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Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7

Biochimica et biophysica acta. Biomembranes, 2017-05, Vol.1859 (5), p.835-844

2017

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Computer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.8140-8151

2019

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Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation

Cellular and molecular life sciences : CMLS, 2022-12, Vol.79 (12), p.606, Article 606

2022

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The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisin

Peptides (New York, N.Y. : 1980), 2023-09, Vol.167, p.171049-171049, Article 171049

2023

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Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Neuropharmacology, 2017-12, Vol.127, p.32-45

2017

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Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity

Molecules (Basel, Switzerland), 2019-10, Vol.24 (20), p.3739

2019

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New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

Frontiers in microbiology, 2017-05, Vol.8, p.775-775

2017

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Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins

Toxins, 2017-08, Vol.9 (8), p.248

2017

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Optimization of the cyclotide framework to improve cell penetration properties

Frontiers in pharmacology, 2015-02, Vol.6, p.17-17

2015

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Synthesis, Structure, and Activity of the Antifungal Plant Defensin Pv D 1

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9391-9402

2020

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Corrigendum to “Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7” [Biochim. Biophys. Acta 1859(5) (2017) 835–844]

Biochimica et biophysica acta. Biomembranes, 2017-11, Vol.1859 (11), p.2277-2277

2017

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Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa V 1.7

Biochimica et biophysica acta. Biomembranes, 2017-05, Vol.1859 (5), p.835-844

2017

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The Importance of Peptide-Membrane Interactions in Toxin Inhibitions of Sodium Channels

Biophysical journal, 2017-02, Vol.112 (3), p.226a-226a

2017

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Re-evaluating the role of strongly charged sequences in amphipathic cell-penetrating peptides: a fluorescence study using Pep-1

FEBS letters, 2005-08, Vol.579 (20), p.4498-4502

2005

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The Application of Biophysical Techniques to Study Antimicrobial Peptides

Journal of spectroscopy (Hindawi), 2012-01, Vol.2012 (2012), p.1-9

2012

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Converting peptides into drugs targeting intracellular protein–protein interactions

Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics

Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure-Activity Relationships to Therapeutic Applications

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

Investigations into the membrane activity of arenicin antimicrobial peptide AA139

Synthesis, Structure, and Activity of the Antifungal Plant Defensin PvD1

Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7

Computer-Aided Design of Mastoparan-like Peptides Enables the Generation of Nontoxic Variants with Extended Antibacterial Properties

Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation

The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisin

Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Evaluation of Cyclic Peptide Inhibitors of the Grb7 Breast Cancer Target: Small Change in Cargo Results in Large Change in Cellular Activity

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins

Optimization of the cyclotide framework to improve cell penetration properties

Synthesis, Structure, and Activity of the Antifungal Plant Defensin Pv D 1

Corrigendum to “Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7” [Biochim. Biophys. Acta 1859(5) (2017) 835–844]

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNa V 1.7

The Importance of Peptide-Membrane Interactions in Toxin Inhibitions of Sodium Channels

Re-evaluating the role of strongly charged sequences in amphipathic cell-penetrating peptides: a fluorescence study using Pep-1

The Application of Biophysical Techniques to Study Antimicrobial Peptides

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