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Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42

Pharmacological research, 2024-05, Vol.203, p.107165-107165, Article 107165

2024

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Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?

Biomolecules (Basel, Switzerland), 2015-09, Vol.5 (4), p.2417-2434

2015

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Rac1 Protein Signaling Is Required for DNA Damage Response Stimulated by Topoisomerase II Poisons

The Journal of biological chemistry, 2012-11, Vol.287 (46), p.38590-38599

2012

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Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers

Cell death & disease, 2017-01, Vol.8 (1), p.e2564-e2564

2017

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The lipid lowering drug lovastatin protects against doxorubicin-induced hepatotoxicity

Toxicology and applied pharmacology, 2012-05, Vol.261 (1), p.66-73

2012

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Nuclear RAC1 is a modulator of the doxorubicin-induced DNA damage response

Biochimica et biophysica acta. Molecular cell research, 2022-10, Vol.1869 (10), p.119320-119320, Article 119320

2022

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Modulation of Rho-regulated pathways for the prevention of doxorubicin induced cardiotoxicity: Sanofi-Aventis-Preis 2014 (Poster)

Biospektrum, 2014-09, Vol.20 (5), p.588-588

Henninger, Christian

2014

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Modulation of Rho-regulated pathways for the prevention of doxorubicin induced cardiotoxicity

Biospektrum, 2014-09, Vol.20 (5), p.588-588

Henninger, Christian

2014

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Diffusion weighted imaging for the detection and evaluation of cholesteatoma

World journal of radiology, 2017-05, Vol.9 (5), p.217-222

2017

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Distinct contribution of Rac1 expression in cardiomyocytes to anthracycline-induced cardiac injury

Biochemical pharmacology, 2019-06, Vol.164, p.82-93

2019

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Hepatic Rac1 GTPase contributes to liver-mediated basal immune homeostasis and LPS-induced endotoxemia

Biochimica et biophysica acta. Molecular cell research, 2018-09, Vol.1865 (9), p.1277-1292

2018

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Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity

Archives of toxicology, 2018, Vol.92 (1), p.441-453

2018

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Chronic heart damage following doxorubicin treatment is alleviated by lovastatin

Pharmacological research, 2015-01, Vol.91, p.47-56

2015

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DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac

Biochimica et biophysica acta, 2013-12, Vol.1833 (12), p.3093-3103

2013

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Rho inhibition by lovastatin affects apoptosis and DSB repair of primary human lung cells in vitro and lung tissue in vivo following fractionated irradiation

Cell death & disease, 2017-08, Vol.8 (8), p.e2978-e2978

2017

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Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents

British medical bulletin, 2011-03, Vol.97 (1), p.17-26

2011

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Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells

Toxicology and applied pharmacology, 2016-02, Vol.292, p.103-114

2016

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Rac1 promotes diethylnitrosamine (DEN)-induced formation of liver tumors

Carcinogenesis (New York), 2015-03, Vol.36 (3), p.378-389

2015

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Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury

Biochimica et biophysica acta, 2015-03, Vol.1853 (3), p.685-698

2015

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Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity

Anti-cancer drugs, 2014-09, Vol.25 (8), p.917-929

2014

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Designer Thiopurine-analogues for Optimised Immunosuppression in Inflammatory Bowel Diseases

Journal of Crohn's and colitis, 2016-10, Vol.10 (10), p.1132-1143

2016

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Mo1714 Designer Thiopurine Analogues for Optimized Immunosuppressive Therapy of Inflammatory Bowel Disease

Gastroenterology (New York, N.Y. 1943), 2014-05, Vol.146 (5), p.S-642-S-642

2014

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Sa1781 Thiopurine Analogues for Optimized RAC1/Vav1 Blockade in Inflammatory Bowel Diseases

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-304-S-305

2013

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S1775 Development of a New Class of Thiopurine-Based Immunosuppressive Agents: Improved Ratio Between High Immunosuppressive Effects and Low Associated Toxicity

Gastroenterology (New York, N.Y. 1943), 2010, Vol.138 (5), p.S-271-S-271

2010

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A comparison of NER tools w.r.t. a domain-specific vocabulary

Proceedings of the 10th International Conference on semantic systems, 2014, p.100-107

2014

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Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42

Rho GTPases: Novel Players in the Regulation of the DNA Damage Response?

Rac1 Protein Signaling Is Required for DNA Damage Response Stimulated by Topoisomerase II Poisons

Statins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers

The lipid lowering drug lovastatin protects against doxorubicin-induced hepatotoxicity

Nuclear RAC1 is a modulator of the doxorubicin-induced DNA damage response

Modulation of Rho-regulated pathways for the prevention of doxorubicin induced cardiotoxicity: Sanofi-Aventis-Preis 2014 (Poster)

Modulation of Rho-regulated pathways for the prevention of doxorubicin induced cardiotoxicity

Diffusion weighted imaging for the detection and evaluation of cholesteatoma

Distinct contribution of Rac1 expression in cardiomyocytes to anthracycline-induced cardiac injury

Hepatic Rac1 GTPase contributes to liver-mediated basal immune homeostasis and LPS-induced endotoxemia

Rac1-mediated cardiac damage causes diastolic dysfunction in a mouse model of subacute doxorubicin-induced cardiotoxicity

Chronic heart damage following doxorubicin treatment is alleviated by lovastatin

DNA damage response (DDR) induced by topoisomerase II poisons requires nuclear function of the small GTPase Rac

Rho inhibition by lovastatin affects apoptosis and DSB repair of primary human lung cells in vitro and lung tissue in vivo following fractionated irradiation

Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents

Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells

Rac1 promotes diethylnitrosamine (DEN)-induced formation of liver tumors

Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury

Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity

Designer Thiopurine-analogues for Optimised Immunosuppression in Inflammatory Bowel Diseases

Mo1714 Designer Thiopurine Analogues for Optimized Immunosuppressive Therapy of Inflammatory Bowel Disease

Sa1781 Thiopurine Analogues for Optimized RAC1/Vav1 Blockade in Inflammatory Bowel Diseases

S1775 Development of a New Class of Thiopurine-Based Immunosuppressive Agents: Improved Ratio Between High Immunosuppressive Effects and Low Associated Toxicity

A comparison of NER tools w.r.t. a domain-specific vocabulary

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