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Avoiding future controversies in the Alzheimer's disease space through understanding the aducanumab data and FDA review

Alzheimer's research & therapy, 2023-05, Vol.15 (1), p.98-98, Article 98

2023

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Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial

Lancet neurology, 2008-06, Vol.7 (6), p.483-493

2008

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The Alzheimer's Prevention Initiative Composite Cognitive Test: a practical measure for tracking cognitive decline in preclinical Alzheimer's disease

Alzheimer's research & therapy, 2020-05, Vol.12 (1), p.66-66, Article 66

2020

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Cumulative, additive benefits of memantine-donepezil combination over component monotherapies in moderate to severe Alzheimer's dementia: a pooled area under the curve analysis

Alzheimer's research & therapy, 2015-05, Vol.7 (1), p.28-28, Article 28

2015

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36‐month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease

Alzheimer's & dementia, 2021-01, Vol.17 (1), p.29-40

2021

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Sensory, mechanical, and microscopic evaluation of staling in low-protein and gluten-free breads

Cereal chemistry, 2005-05, Vol.82 (3), p.328-335

2005

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ADCOMS: a composite clinical outcome for prodromal Alzheimer's disease trials

Journal of neurology, neurosurgery and psychiatry, 2016-09, Vol.87 (9), p.993-999

2016

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24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

Lancet neurology, 2017-12, Vol.16 (12), p.965-975

2017

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GenoRisk: A polygenic risk score for Alzheimer's disease

Alzheimer's & dementia : translational research & clinical interventions, 2021, Vol.7 (1), p.e12211-n/a

2021

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Not sexy enough: the uphill battle faced by non‐traditional treatments in the U.S. despite having the most compelling AD results to date

Alzheimer's & dementia, 2022-12, Vol.18 (S9), p.e068373-n/a

2022

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An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease

Alzheimer's & dementia, 2014-11, Vol.10 (6), p.666-674

2014

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Value-Generating Exploratory Trials in Neurodegenerative Dementias

Neurology, 2021-05, Vol.96 (20), p.944-954

2021

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The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers

The journal of clinical psychiatry, 2014-06, Vol.75 (6), p.652-660

2014

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Meaningful Clinical Changes in Alzheimer Disease Measured With the iADRS and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings

Neurology. Clinical practice, 2023-04, Vol.13 (2), p.e200127-e200127

2023

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Safety, tolerability, immunogenicity, and efficacy of UB-311 in participants with mild Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 2a study

EBioMedicine, 2023-08, Vol.94, p.104665-104665, Article 104665

2023

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Perspectives on statistical strategies for the regulatory biomarker qualification process

Biomarkers in medicine, 2021-06, Vol.15 (9), p.669-684

2021

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Measuring clinical progression in MCI and pre-MCI populations: enrichment and optimizing clinical outcomes over time

Alzheimer's research & therapy, 2012-01, Vol.4 (4), p.24-24

Hendrix, Suzanne B

2012

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Multivariate analysis for the biobehavioral and social sciences: a graphical approach

1st ed., 2011

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Development of a General Composite Scale (GENCOMS) for Progressive Neurodegenerative Diseases and Implications for the Assessment of Disease-Modifying Therapies

Neurology and therapy, 2024-09

2024

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Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype

Journal of Alzheimer's disease, 2017-01, Vol.57 (2), p.447-459

2017

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Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial

Alzheimer's research & therapy, 2021-03, Vol.13 (1), p.64-64, Article 64

2021

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Separation of cognitive domains to improve prediction of progression from mild cognitive impairment to Alzheimer's disease

Alzheimer's research & therapy, 2013-01, Vol.5 (3), p.22-22

2013

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F2‐03‐03: ADCOMS: A SENSITIVE MEASURE OF DISEASE PROGRESSION IN EARLY AD SUPPORTING BETTER DEVELOPMENT DECISIONS

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_10), p.P520-P520

2019

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ADCOMS: A SENSITIVE MEASURE OF DISEASE PROGRESSION IN EARLY AD SUPPORTING BETTER DEVELOPMENT DECISIONS

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P520-P520

2019

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Time Course of Cognitive Decline in Subjects With Mild Alzheimer's Disease Based on ADAS-cog Subscales and Neuropsychological Tests Measured in ADNI

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.e50-e50

2010

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Avoiding future controversies in the Alzheimer's disease space through understanding the aducanumab data and FDA review

Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial

The Alzheimer's Prevention Initiative Composite Cognitive Test: a practical measure for tracking cognitive decline in preclinical Alzheimer's disease

Cumulative, additive benefits of memantine-donepezil combination over component monotherapies in moderate to severe Alzheimer's dementia: a pooled area under the curve analysis

36‐month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's disease

Sensory, mechanical, and microscopic evaluation of staling in low-protein and gluten-free breads

ADCOMS: a composite clinical outcome for prodromal Alzheimer's disease trials

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

GenoRisk: A polygenic risk score for Alzheimer's disease

Not sexy enough: the uphill battle faced by non‐traditional treatments in the U.S. despite having the most compelling AD results to date

An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease

Value-Generating Exploratory Trials in Neurodegenerative Dementias

The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers

Meaningful Clinical Changes in Alzheimer Disease Measured With the iADRS and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings

Safety, tolerability, immunogenicity, and efficacy of UB-311 in participants with mild Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 2a study

Perspectives on statistical strategies for the regulatory biomarker qualification process

Measuring clinical progression in MCI and pre-MCI populations: enrichment and optimizing clinical outcomes over time

Multivariate analysis for the biobehavioral and social sciences: a graphical approach

Development of a General Composite Scale (GENCOMS) for Progressive Neurodegenerative Diseases and Implications for the Assessment of Disease-Modifying Therapies

Cognitive Composites Domain Scores Related to Neuroimaging Biomarkers within Probable-Amnestic Mild Cognitive Impairment-Storage Subtype

Research diagnostic criteria for Alzheimer's disease: findings from the LipiDiDiet randomized controlled trial

Separation of cognitive domains to improve prediction of progression from mild cognitive impairment to Alzheimer's disease

F2‐03‐03: ADCOMS: A SENSITIVE MEASURE OF DISEASE PROGRESSION IN EARLY AD SUPPORTING BETTER DEVELOPMENT DECISIONS

ADCOMS: A SENSITIVE MEASURE OF DISEASE PROGRESSION IN EARLY AD SUPPORTING BETTER DEVELOPMENT DECISIONS

Time Course of Cognitive Decline in Subjects With Mild Alzheimer's Disease Based on ADAS-cog Subscales and Neuropsychological Tests Measured in ADNI

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