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Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential

Cell reports (Cambridge), 2015-05, Vol.11 (5), p.808-820

2015

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Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (24), p.10234-10242

2010

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Re‐examining a strong recommendation based on low‐quality evidence in acute chest syndrome

Pediatric blood & cancer, 2023-05, Vol.70 (5), p.e30266-n/a

Hemenway, Charles S.

2023

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An Atypical Presentation of Hodgkin Lymphoma Invading the Myocardium

Journal of pediatric hematology/oncology, 2023-08, Vol.45 (6), p.349-351

2023

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Emergence of a Ph-negative Clone in a Child With Ph+ ALL

Journal of pediatric hematology/oncology, 2020-08, Vol.42 (6), p.e466-e468

2020

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CBX8, a component of the Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3

FEBS letters, 2013-09, Vol.587 (18), p.3038-3044

2013

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Dot1a-AF9 Complex Mediates Histone H3 Lys-79 Hypermethylation and Repression of ENaCα in an Aldosterone-sensitive Manner

The Journal of biological chemistry, 2006-06, Vol.281 (26), p.18059-18068

2006

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Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases

Expert opinion on biological therapy, 2005-12, Vol.5 (12), p.1571-1584

2005

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Hsp90 Directly Modulates the Spatial Distribution of AF9/MLLT3 and Affects Target Gene Expression

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.11966-11973

2010

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Calcineurin. Structure, function, and inhibition

Cell biochemistry and biophysics, 1999, Vol.30 (1), p.115-151

1999

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An AF9/ENL-targted peptide with therapeutic potential in mixed lineage leukemias

Journal of experimental therapeutics & oncology, 2014, Vol.10 (4), p.293-300

2014

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Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4

Leukemia research, 2014-11, Vol.38 (11), p.1309-1315

2014

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The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor

Oncogene, 2003-05, Vol.22 (22), p.3395-3406

2003

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The AF4-mimetic peptide, PFWT, induces necrotic cell death in MV4-11 leukemia cells

Leukemia research, 2008-04, Vol.32 (4), p.633-642

2008

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Title: MLLT1 Is Required to Maintain Normal B-Lineage Hematopoiesis and Mitochondrial Function

Blood, 2023-11, Vol.142 (Supplement 1), p.5585-5585

2023

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Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents

Leukemia research, 2009-07, Vol.33 (7), p.937-947

2009

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The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias

Oncogene, 2001-06, Vol.20 (29), p.3798-3805

2001

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Hurricane Katrina's impact on pediatric and adult patients with sickle cell disease

Journal of health care for the poor and underserved, 2007-05, Vol.18 (2), p.382-393

2007

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CBX8, a component of the repressive Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3

FEBS letters, 2013-07, Vol.587 (18), p.3038-3044

2013

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Abstract 761: Importance of protein interactions in mediating AF9/MLLT3 function

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.761-761

2013

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Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains

Proceedings of the National Academy of Sciences - PNAS, 1994-06, Vol.91 (12), p.5372-5376

1994

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Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in Yeast

The Journal of biological chemistry, 1996-08, Vol.271 (31), p.18527-18534

1996

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The Bmi-1 oncoprotein interacts with dinG and MPh2 : the role of RING finger domains

Oncogene, 1998-05, Vol.16 (19), p.2541-2547

1998

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Abstract 278: Role of AF4 and Dot1 in MLL-AF9 mediated leukemogenesis

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.278-278

2011

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Abstract 616: AF4-AF9 interaction as a potential therapeutic target for MLL-rearranged mixed-lineage leukemias

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.616-616

2011

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Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes

Re‐examining a strong recommendation based on low‐quality evidence in acute chest syndrome

An Atypical Presentation of Hodgkin Lymphoma Invading the Myocardium

Emergence of a Ph-negative Clone in a Child With Ph+ ALL

CBX8, a component of the Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3

Dot1a-AF9 Complex Mediates Histone H3 Lys-79 Hypermethylation and Repression of ENaCα in an Aldosterone-sensitive Manner

Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases

Hsp90 Directly Modulates the Spatial Distribution of AF9/MLLT3 and Affects Target Gene Expression

Calcineurin. Structure, function, and inhibition

An AF9/ENL-targted peptide with therapeutic potential in mixed lineage leukemias

Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4

The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor

The AF4-mimetic peptide, PFWT, induces necrotic cell death in MV4-11 leukemia cells

Title: MLLT1 Is Required to Maintain Normal B-Lineage Hematopoiesis and Mitochondrial Function

Molecular targeting of MLL-rearranged leukemia cell lines with the synthetic peptide PFWT synergistically enhances the cytotoxic effect of established chemotherapeutic agents

The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias

Hurricane Katrina's impact on pediatric and adult patients with sickle cell disease

CBX8, a component of the repressive Polycomb PRC1 complex, modulates DOT1L-mediated gene expression through AF9/MLLT3

Abstract 761: Importance of protein interactions in mediating AF9/MLLT3 function

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains

Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in Yeast

The Bmi-1 oncoprotein interacts with dinG and MPh2 : the role of RING finger domains

Abstract 278: Role of AF4 and Dot1 in MLL-AF9 mediated leukemogenesis

Abstract 616: AF4-AF9 interaction as a potential therapeutic target for MLL-rearranged mixed-lineage leukemias

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