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Comparison of mechanistic transport cycle models of ABC exporters

Biochimica et biophysica acta. Biomembranes, 2018-04, Vol.1860 (4), p.818-832

2018

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What monomeric nucleotide binding domains can teach us about dimeric ABC proteins

FEBS letters, 2020-12, Vol.594 (23), p.3857-3875

2020

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Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk

Nature communications, 2019-09, Vol.10 (1), p.4378-14, Article 4378

2019

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Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (23), p.9553-9558

2013

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Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity

Nature communications, 2023-07, Vol.14 (1), p.4165-4165, Article 4165

2023

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Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and Kinetics

Molecules (Basel, Switzerland), 2020-04, Vol.25 (9), p.2064

2020

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Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension

Nature communications, 2021-03, Vol.12 (1), p.1444-1444, Article 1444

2021

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Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function

Nature communications, 2022-12, Vol.13 (1), p.7483-7483, Article 7483

2022

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New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain

Molecules (Basel, Switzerland), 2020-03, Vol.25 (6), p.1451

2020

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Dynamic ion channel defies dogma

Nature (London), 2023-09, Vol.621 (7977), p.46-47

Hellmich, Ute A.

2023

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Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis

Molecules (Basel, Switzerland), 2022-06, Vol.27 (12), p.3765

2022

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Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport

Biochimica et biophysica acta. Biomembranes, 2018-04, Vol.1860 (4), p.927-942

2018

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Diverse relations between ABC transporters and lipids: An overview

Biochimica et biophysica acta. Biomembranes, 2017-04, Vol.1859 (4), p.605-618

2017

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Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR

Nature chemical biology, 2011-05, Vol.7 (5), p.263

2011

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Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold

Computational and structural biotechnology journal, 2024-12, Vol.23, p.473-482

2024

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Probing the ATP Hydrolysis Cycle of the ABC Multidrug Transporter LmrA by Pulsed EPR Spectroscopy

Journal of the American Chemical Society, 2012-04, Vol.134 (13), p.5857-5862

2012

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Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA–protein interactions during small ribosomal subunit biogenesis

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (38), p.15253-15258

2013

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TRP channels: branching out into the fungal kingdom

Structure (London), 2022-01, Vol.30 (1), p.2-4

2022

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Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97

Communications chemistry, 2022-12, Vol.5 (1), p.169-15, Article 169

2022

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Unstructural Biology of TRP Ion Channels: The Role of Intrinsically Disordered Regions in Channel Function and Regulation

Journal of molecular biology, 2021-08, Vol.433 (17), p.166931-166931, Article 166931

2021

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TRPV4 mutations causing mixed neuropathy and skeletal phenotypes result in severe gain of function

Annals of clinical and translational neurology, 2022-03, Vol.9 (3), p.375-391

2022

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NMR and EPR studies of membrane transporters

Biological chemistry, 2009-08, Vol.390 (8), p.815-834

2009

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IM30 IDPs form a membrane-protective carpet upon super-complex disassembly

Communications biology, 2020-10, Vol.3 (1), p.595-595, Article 595

2020

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Functional modulation of chemical mediators in microbial communities

Trends in biochemical sciences (Amsterdam. Regular ed.), 2023-01, Vol.48 (1), p.71-81

2023

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Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes

The Journal of biological chemistry, 2021-01, Vol.296, p.100565, Article 100565

2021

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Comparison of mechanistic transport cycle models of ABC exporters

What monomeric nucleotide binding domains can teach us about dimeric ABC proteins

Methionine in a protein hydrophobic core drives tight interactions required for assembly of spider silk

Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli

Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity

Naphthoquinones as Covalent Reversible Inhibitors of Cysteine Proteases-Studies on Inhibition Mechanism and Kinetics

Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension

Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function

New Cysteine Protease Inhibitors: Electrophilic (Het)arenes and Unexpected Prodrug Identification for the Trypanosoma Protease Rhodesain

Dynamic ion channel defies dogma

Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis

Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport

Diverse relations between ABC transporters and lipids: An overview

Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR

Experimental and computational biophysics to identify vasodilator drugs targeted at TRPV2 using agonists based on the probenecid scaffold

Probing the ATP Hydrolysis Cycle of the ABC Multidrug Transporter LmrA by Pulsed EPR Spectroscopy

Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA–protein interactions during small ribosomal subunit biogenesis

TRP channels: branching out into the fungal kingdom

Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97

Unstructural Biology of TRP Ion Channels: The Role of Intrinsically Disordered Regions in Channel Function and Regulation

TRPV4 mutations causing mixed neuropathy and skeletal phenotypes result in severe gain of function

NMR and EPR studies of membrane transporters

IM30 IDPs form a membrane-protective carpet upon super-complex disassembly

Functional modulation of chemical mediators in microbial communities

Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes

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