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Targeting the PDGF signaling pathway in tumor treatment

Cell communication and signaling, 2013-12, Vol.11 (1), p.97-97

Heldin, Carl-Henrik

2013

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Signaling networks guiding epithelial–mesenchymal transitions during embryogenesis and cancer progression

Cancer science, 2007-10, Vol.98 (10), p.1512-1520

2007

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Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors

Bone (New York, N.Y.), 2020-09, Vol.138, p.115472-115472, Article 115472

2020

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Genome–wide binding of transcription factor ZEB1 in triple‐negative breast cancer cells

Journal of cellular physiology, 2018-10, Vol.233 (10), p.7113-7127

2018

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Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2

Journal of cellular physiology, 2015-12, Vol.230 (12), p.3084-3092

2015

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TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness

Oncogene, 2020-05, Vol.39 (22), p.4436-4449

2020

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Signaling Receptors for TGF-β Family Members

Cold Spring Harbor perspectives in biology, 2016-08, Vol.8 (8), p.a022053

2016

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Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma

Cell death and differentiation, 2018-05, Vol.25 (5), p.885-903

2018

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Tumor Promoting Effect of BMP Signaling in Endometrial Cancer

International journal of molecular sciences, 2021-07, Vol.22 (15), p.7882

2021

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High interstitial fluid pressure - an obstacle in cancer therapy

Nature reviews. Cancer, 2004-10, Vol.4 (10), p.806-813

2004

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ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

Nucleic acids research, 2011-11, Vol.39 (20), p.8712-8727

2011

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Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth

The Journal of pathology, 2018-12, Vol.246 (4), p.447-458

2018

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Targeting the PDGF Signaling Pathway in the Treatment of Non-Malignant Diseases

Journal of neuroimmune pharmacology, 2014-03, Vol.9 (2), p.69-79

Heldin, Carl-Henrik

2014

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HMGA2 and Smads Co-regulate SNAIL1 Expression during Induction of Epithelial-to-Mesenchymal Transition

The Journal of biological chemistry, 2008-11, Vol.283 (48), p.33437-33446

2008

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The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial‐mesenchymal transition

Journal of cellular physiology, 2023-04, Vol.238 (4), p.790-812

2023

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The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ

International journal of molecular sciences, 2023-04, Vol.24 (9), p.7782

2023

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Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells

Cell death & disease, 2022-09, Vol.13 (9), p.832-832, Article 832

2022

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The protein kinase LKB1 promotes self‐renewal and blocks invasiveness in glioblastoma

Journal of cellular physiology, 2022-01, Vol.237 (1), p.743-762

2022

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CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence

Cancers, 2022-07, Vol.14 (15), p.3747

2022

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BMP2-induction of FN14 promotes protumorigenic signaling in gynecologic cancer cells

Cellular signalling, 2021-11, Vol.87, p.110146-110146, Article 110146

2021

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Regulation of EMT by TGFβ in cancer

FEBS letters, 2012-07, Vol.586 (14), p.1959-1970

2012

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Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16), p.3345-3358

2020

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Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling

Cellular and molecular life sciences : CMLS, 2022-02, Vol.79 (2), p.85-85, Article 85

2022

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The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition

Nucleic acids research, 2015-01, Vol.43 (1), p.162-178

2015

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The TGFβ superfamily in Lisbon: navigating through development and disease

Development (Cambridge), 2017-12, Vol.144 (24), p.4476-4480

2017

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Targeting the PDGF signaling pathway in tumor treatment

Signaling networks guiding epithelial–mesenchymal transitions during embryogenesis and cancer progression

Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors

Genome–wide binding of transcription factor ZEB1 in triple‐negative breast cancer cells

Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2

TGFβ and EGF signaling orchestrates the AP-1- and p63 transcriptional regulation of breast cancer invasiveness

Signaling Receptors for TGF-β Family Members

Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma

Tumor Promoting Effect of BMP Signaling in Endometrial Cancer

High interstitial fluid pressure - an obstacle in cancer therapy

ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif

Targeting PDGF‐mediated recruitment of pericytes blocks vascular mimicry and tumor growth

Targeting the PDGF Signaling Pathway in the Treatment of Non-Malignant Diseases

HMGA2 and Smads Co-regulate SNAIL1 Expression during Induction of Epithelial-to-Mesenchymal Transition

The liver kinase B1 supports mammary epithelial morphogenesis by inhibiting critical factors that mediate epithelial‐mesenchymal transition

The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ

Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells

The protein kinase LKB1 promotes self‐renewal and blocks invasiveness in glioblastoma

CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence

BMP2-induction of FN14 promotes protumorigenic signaling in gynecologic cancer cells

Regulation of EMT by TGFβ in cancer

Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis

Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling

The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition

The TGFβ superfamily in Lisbon: navigating through development and disease

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