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Mitochondrial dysfunction and longevity in animals: Untangling the knot

Science (American Association for the Advancement of Science), 2015-12, Vol.350 (6265), p.1204-1207

2015

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Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling

The Journal of cell biology, 2018-06, Vol.217 (6), p.1915-1928

2018

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A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

PLoS biology, 2010-12, Vol.8 (12), p.e1000556

2010

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The Intrinsic Apoptosis Pathway Mediates the Pro-Longevity Response to Mitochondrial ROS in C. elegans

Cell, 2014-05, Vol.157 (4), p.897-909

2014

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Superoxide dismutase is dispensable for normal animal lifespan

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (15), p.5785-5790

2012

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Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

Aging cell, 2010-06, Vol.9 (3), p.433-447

2010

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Minimal mitochondrial respiration is required to prevent cell death by inhibition of mTOR signaling in CoQ-deficient cells

Cell death discovery, 2021-08, Vol.7 (1), p.201-201, Article 201

2021

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Micellization of coenzyme Q by the fungicide caspofungin allows for safe intravenous administration to reach extreme supraphysiological concentrations

Redox biology, 2020-09, Vol.36, p.101680, Article 101680

2020

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Early Mitochondrial Dysfunction in Long-lived Mclk1+/- Mice

The Journal of biological chemistry, 2008-09, Vol.283 (38), p.26217-26227

2008

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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

PLoS genetics, 2009-02, Vol.5 (2), p.e1000361

2009

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Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

Aging cell, 2015-10, Vol.14 (5), p.887-895

2015

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Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers

Frontiers in genetics, 2016-09, Vol.7, p.161-161

2016

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Molecular genetics of ubiquinone biosynthesis in animals

Critical reviews in biochemistry and molecular biology, 2013-01, Vol.48 (1), p.69-88

2013

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Genetics and the Specificity of the Aging Process

Science (American Association for the Advancement of Science), 2003-02, Vol.299 (5611), p.1351-1354

2003

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FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1

Mechanisms of ageing and development, 2011-10, Vol.132 (10), p.519-521

2011

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A Measurable Increase in Oxidative Damage Due to Reduction in Superoxide Detoxification Fails to Shorten the Life Span of Long-Lived Mitochondrial Mutants of Caenorhabditis elegans

Genetics (Austin), 2007-12, Vol.177 (4), p.2063-2074

2007

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A novel COQ7 mutation causing primarily neuromuscular pathology and its treatment options

Molecular genetics and metabolism reports, 2022-06, Vol.31, p.100877-100877, Article 100877

2022

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Understanding Ubiquinone

Trends in cell biology, 2016-05, Vol.26 (5), p.367-378

2016

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Mitochondrial and cytoplasmic ROS have opposing effects on lifespan

PLoS genetics, 2015-02, Vol.11 (2), p.e1004972-e1004972

2015

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Making a splash with splicing

Cell research, 2017-04, Vol.27 (4), p.457-458

2017

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ROS regulation of RAS and vulva development in Caenorhabditis elegans

PLoS genetics, 2020-06, Vol.16 (6), p.e1008838

2020

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Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

Genes & development, 2005-10, Vol.19 (20), p.2424-2434

2005

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Antioxidants reveal an inverted U‐shaped dose‐response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans

Aging cell, 2017-02, Vol.16 (1), p.104-112

2017

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The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice

The Journal of cell biology, 2012-10, Vol.199 (2), p.215-224

2012

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A single biochemical activity underlies the pleiotropy of the aging-related protein CLK-1

Scientific reports, 2017-04, Vol.7 (1), p.859-14, Article 859

2017

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Mitochondrial dysfunction and longevity in animals: Untangling the knot

Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling

A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans

The Intrinsic Apoptosis Pathway Mediates the Pro-Longevity Response to Mitochondrial ROS in C. elegans

Superoxide dismutase is dispensable for normal animal lifespan

Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

Minimal mitochondrial respiration is required to prevent cell death by inhibition of mTOR signaling in CoQ-deficient cells

Micellization of coenzyme Q by the fungicide caspofungin allows for safe intravenous administration to reach extreme supraphysiological concentrations

Early Mitochondrial Dysfunction in Long-lived Mclk1+/- Mice

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers

Molecular genetics of ubiquinone biosynthesis in animals

Genetics and the Specificity of the Aging Process

FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1

A Measurable Increase in Oxidative Damage Due to Reduction in Superoxide Detoxification Fails to Shorten the Life Span of Long-Lived Mitochondrial Mutants of Caenorhabditis elegans

A novel COQ7 mutation causing primarily neuromuscular pathology and its treatment options

Understanding Ubiquinone

Mitochondrial and cytoplasmic ROS have opposing effects on lifespan

Making a splash with splicing

ROS regulation of RAS and vulva development in Caenorhabditis elegans

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

Antioxidants reveal an inverted U‐shaped dose‐response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans

The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1+/- mice

A single biochemical activity underlies the pleiotropy of the aging-related protein CLK-1

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