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Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F

Molecular and Cellular Biology, 1993-12, Vol.13 (12), p.7802-7812

1993

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Evaluation of farnesyl:Protein transferase and geranylgeranyl:Protein transferase inhibitor combinations in preclinical models

Cancer research (Chicago, Ill.), 2001-12, Vol.61 (24), p.8758-8768

2001

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Identification of a novel retinoblastoma gene product binding site on human papillomavirus type 16 E7 protein

The Journal of biological chemistry, 1994-03, Vol.269 (9), p.6842-6850

1994

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Protein domains governing interactions between E2F, the retinoblastoma gene product, and human papillomavirus type 16 E7 protein

Molecular and Cellular Biology, 1993-02, Vol.13 (2), p.953-960

1993

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Transcription Factor E2F Binds DNA as a Heterodimer

Proceedings of the National Academy of Sciences - PNAS, 1993-04, Vol.90 (8), p.3525-3529

1993

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Phase I clinical study of the recombinant oncotoxin TP40 in superficial bladder cancer

Clinical cancer research, 1995-01, Vol.1 (1), p.57-61

1995

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Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein

The Journal of biological chemistry, 1990-08, Vol.265 (22), p.12782-12785

1990

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Small-Molecule MDM2 Antagonists Reveal Aberrant P53 Signaling in Cancer: Implications for Therapy

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (6), p.1888-1893

2006

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Transforming Growth Factor α-Pseudomonas Exotoxin Fusion Protein Prolongs Survival of Nude Mice Bearing Tumor Xenografts

Proceedings of the National Academy of Sciences - PNAS, 1990-06, Vol.87 (12), p.4697-4701

1990

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Therapeutic intervention and signaling

Current opinion in cell biology, 1998-04, Vol.10 (2), p.284-288

1998

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Human papillomavirus type 16 E7 protein inhibits DNA binding by the retinoblastoma gene product

Molecular and Cellular Biology, 1992-05, Vol.12 (5), p.1905-1914

1992

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Copper-dependent cleavage of DNA by bleomycin

Biochemistry (Easton), 1987-02, Vol.26 (3), p.931-942

1987

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Carboxyl-terminal Modification of a Gastrin Releasing Peptide Derivative Generates Potent Antagonists

The Journal of biological chemistry, 1989-07, Vol.264 (19), p.11258-11262

1989

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Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors

Cancer research (Chicago, Ill.), 2005-03, Vol.65 (5), p.1918-1924

2005

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Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

The Journal of biological chemistry, 2004-12, Vol.279 (51), p.53015-53022

2004

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Minimal ligand analysis of gastrin releasing peptide. Receptor binding and mitogenesis

The Journal of biological chemistry, 1988-05, Vol.263 (15), p.7016-7019

1988

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Purification and characterization of a functionally homogeneous 60-kDa species of the retinoblastoma gene product

The Journal of biological chemistry, 1992-04, Vol.267 (12), p.7971-7974

1992

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High-Density Functional Gastrin Releasing Peptide Receptors on Primate Cells

JNCI : Journal of the National Cancer Institute, 1990-03, Vol.82 (5), p.402-407

1990

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Epidermal growth factor receptor binding is affected by structural determinants in the toxin domain of transforming growth factor-alpha-Pseudomonas exotoxin fusion proteins

Molecular and Cellular Biology, 1989-07, Vol.9 (7), p.2860-2867

1989

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Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein

The Journal of biological chemistry, 1992-01, Vol.267 (2), p.908-912

1992

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Anions Modulate the Potency of Geranylgeranyl-Protein Transferase I Inhibitors

The Journal of biological chemistry, 2001-07, Vol.276 (27), p.24457-24465

2001

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Biochemistry of misonidazole reduction by NADPH-cytochrome c (P-450) reductase

Molecular pharmacology, 1986-02, Vol.29 (2), p.168-172

1986

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Retinoblastoma protein binding properties are dependent on 4 cysteine residues in the protein binding pocket

The Journal of biological chemistry, 1992-07, Vol.267 (21), p.14846-14851

1992

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Characterization of functional HPV-16 E7 protein produced in Escherichia coli

The Journal of biological chemistry, 1992-04, Vol.267 (10), p.6910-6915

1992

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Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F

Evaluation of farnesyl:Protein transferase and geranylgeranyl:Protein transferase inhibitor combinations in preclinical models

Identification of a novel retinoblastoma gene product binding site on human papillomavirus type 16 E7 protein

Protein domains governing interactions between E2F, the retinoblastoma gene product, and human papillomavirus type 16 E7 protein

Transcription Factor E2F Binds DNA as a Heterodimer

Phase I clinical study of the recombinant oncotoxin TP40 in superficial bladder cancer

Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein

Small-Molecule MDM2 Antagonists Reveal Aberrant P53 Signaling in Cancer: Implications for Therapy

Transforming Growth Factor α-Pseudomonas Exotoxin Fusion Protein Prolongs Survival of Nude Mice Bearing Tumor Xenografts

Therapeutic intervention and signaling

Human papillomavirus type 16 E7 protein inhibits DNA binding by the retinoblastoma gene product

Copper-dependent cleavage of DNA by bleomycin

Carboxyl-terminal Modification of a Gastrin Releasing Peptide Derivative Generates Potent Antagonists

Design and Biological Activity of (S)-4-(5-{[1-(3-Chlorobenzyl)-2- oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-Aminopyrrolidinone Farnesyltransferase Inhibitor with Excellent Cell Potency

Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors

Phosphorylation of p53 on Key Serines Is Dispensable for Transcriptional Activation and Apoptosis

Minimal ligand analysis of gastrin releasing peptide. Receptor binding and mitogenesis

Purification and characterization of a functionally homogeneous 60-kDa species of the retinoblastoma gene product

High-Density Functional Gastrin Releasing Peptide Receptors on Primate Cells

Epidermal growth factor receptor binding is affected by structural determinants in the toxin domain of transforming growth factor-alpha-Pseudomonas exotoxin fusion proteins

Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein

Anions Modulate the Potency of Geranylgeranyl-Protein Transferase I Inhibitors

Biochemistry of misonidazole reduction by NADPH-cytochrome c (P-450) reductase

Retinoblastoma protein binding properties are dependent on 4 cysteine residues in the protein binding pocket

Characterization of functional HPV-16 E7 protein produced in Escherichia coli

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