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T3 Tissue inhibitor of metalloproteinase-3 (TIMP3) protects against inflammatory processes in Interstitial Lung Disease (ILD)

Thorax, 2010-12, Vol.65 (Suppl 4), p.A1-A2

2010

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EPH11 Prevalence, Risk Factors, and Characterization of Individuals with Long COVID Using Electronic Health Records in Over 1.5 Million COVID Cases in England

Value in health, 2023-12, Vol.26 (12), p.S204

2023

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Does dysautonomia contribute to inappropriate sinus tachycardia in patients with post-COVID-19 syndrome?

European heart journal. Acute cardiovascular care, 2024-05, Vol.13 (Supplement_1)

2024

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Cardiac impairment in Long Covid 1-year post SARS-CoV-2 infection

European heart journal, 2022-10, Vol.43 (Supplement_2)

2022

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P26 Measuring the value of a consultant-led Community Respiratory (CORE) Multidisciplinary Team (MDT) in a deprived inner city area: Achieving parity in respiratory care for housebound sick patients

Thorax, 2015-12, Vol.70 (Suppl 3), p.A88

2015

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P26 Measuring the value of a consultant-led Community Respiratory (CORE) Multidisciplinary Team (MDT) in a deprived inner city area: Achieving parity in respiratory care for housebound sick patients: Abstract P26 Table 1

Thorax, 2015-12, Vol.70 (Suppl 3), p.A88-A89

2015

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Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors

PloS one, 2010-11, Vol.5 (11), p.e15535

2010

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Selective inhibition of BET bromodomains

Nature (London), 2010-12, Vol.468 (7327), p.1067-1073

2010

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Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}- N -methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs

Journal of medicinal chemistry, 2021-10, Vol.64 (19), p.14498-14512

2021

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Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein−Protein Interaction

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15949-15972

2021

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Structure of the Epigenetic Oncogene MMSET and Inhibition by N‑Alkyl Sinefungin Derivatives

ACS chemical biology, 2016-11, Vol.11 (11), p.3093-3105

2016

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Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X‑Linked Inhibitor of Apoptosis Protein (XIAP)

Journal of medicinal chemistry, 2017-06, Vol.60 (11), p.4611-4625

2017

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Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe

Chemical science (Cambridge), 2018-12, Vol.9 (45), p.8608-8618

2018

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Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

Journal of medicinal chemistry, 2013-12, Vol.56 (24), p.10183-10187

2013

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A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction

Angewandte Chemie (International ed.), 2014-06, Vol.53 (24), p.6126-6130

2014

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Integrated care policy recommendations for complex multisystem long term conditions and long COVID

Scientific reports, 2024-06, Vol.14 (1), p.13634-14, Article 13634

2024

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ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK

Molecular cancer therapeutics, 2021-10, Vol.20 (10), p.1757-1768

2021

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Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors

ACS medicinal chemistry letters, 2011-05, Vol.2 (5), p.358-362

2011

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Barriers to healthcare access and experiences of stigma: Findings from a coproduced Long Covid case‐finding study

Health expectations : an international journal of public participation in health care and health policy, 2024-04, Vol.27 (2), p.e14037-n/a

2024

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Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study

American journal of respiratory and critical care medicine, 2023-03, Vol.207 (6), p.693-703

2023

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Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor

ACS medicinal chemistry letters, 2022-10, Vol.13 (10), p.1591-1597

2022

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T3 Tissue inhibitor of metalloproteinase-3 (TIMP3) protects against inflammatory processes in Interstitial Lung Disease (ILD)

EPH11 Prevalence, Risk Factors, and Characterization of Individuals with Long COVID Using Electronic Health Records in Over 1.5 Million COVID Cases in England

Does dysautonomia contribute to inappropriate sinus tachycardia in patients with post-COVID-19 syndrome?

Cardiac impairment in Long Covid 1-year post SARS-CoV-2 infection

P26 Measuring the value of a consultant-led Community Respiratory (CORE) Multidisciplinary Team (MDT) in a deprived inner city area: Achieving parity in respiratory care for housebound sick patients

P26 Measuring the value of a consultant-led Community Respiratory (CORE) Multidisciplinary Team (MDT) in a deprived inner city area: Achieving parity in respiratory care for housebound sick patients: Abstract P26 Table 1

Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors

Selective inhibition of BET bromodomains

Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2‑Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery

Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}- N -methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs

Structure–Activity and Structure–Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2‑Related Factor 2 (KEAP1/NRF2) Protein–Protein Interaction

Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein−Protein Interaction

Structure of the Epigenetic Oncogene MMSET and Inhibition by N‑Alkyl Sinefungin Derivatives

Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X‑Linked Inhibitor of Apoptosis Protein (XIAP)

Quantitation of ERK1/2 inhibitor cellular target occupancies with a reversible slow off-rate probe

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction

Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2

Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2

Integrated care policy recommendations for complex multisystem long term conditions and long COVID

ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors

Barriers to healthcare access and experiences of stigma: Findings from a coproduced Long Covid case‐finding study

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study

Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor

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