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Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives

In vitro cellular & developmental biology. Animal, 2021-02, Vol.57 (2), p.104-132

2021

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The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup

Mutation research. Genetic toxicology and environmental mutagenesis, 2015-05, Vol.783, p.23-35

2015

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Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay

Mutation research, 2012-06, Vol.745 (1-2), p.4-10

2012

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The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment

Environmental and molecular mutagenesis, 2010-10, Vol.51 (8-9), p.825-835

2010

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Erythrocyte PIG‐A mutant frequencies in cancer patients receiving cisplatin

Cancer medicine (Malden, MA), 2024-02, Vol.13 (3), p.e6895-n/a

2024

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Transgenic animal models in toxicology: historical perspectives and future outlook

Toxicological sciences, 2011-06, Vol.121 (2), p.207-233

2011

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DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2006-12, Vol.602 (1), p.83-91

2006

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The Genotoxicity of Acrylamide and Glycidamide in Big Blue Rats

Toxicological sciences, 2010-06, Vol.115 (2), p.412-421

2010

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Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes

Environmental and molecular mutagenesis, 2011-12, Vol.52 (9), p.774-783

2011

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Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines

Mutation research, 2011-07, Vol.723 (1), p.58-64

2011

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In vivo genotoxicity of furan in F344 rats at cancer bioassay doses

Toxicology and applied pharmacology, 2012-06, Vol.261 (2), p.164-171

2012

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International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories

Environmental and molecular mutagenesis, 2011-12, Vol.52 (9), p.690-698

2011

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Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adult gpt-delta transgenic mice

Environmental and molecular mutagenesis, 2014-06, Vol.55 (5), p.385-399

2014

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Tight junction disruption by cadmium in an in vitro human airway tissue model

Respiratory research, 2015-02, Vol.16 (1), p.30-30, Article 30

2015

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Manifestation and persistence of Pig-a mutant red blood cells in C57BL/6 mice following single and split doses of N-ethyl-N-nitrosourea

Environmental and molecular mutagenesis, 2011-12, Vol.52 (9), p.766-773

2011

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Report on stage III Pig-a mutation assays using benzo[a]pyrene

Environmental and molecular mutagenesis, 2011-12, Vol.52 (9), p.731-737

2011

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Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, Aristolochic acids

Mutation research, 2013-05, Vol.753 (2), p.82-92

2013

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Evaluating the Toxicity of Cigarette Whole Smoke Solutions in an Air-Liquid-Interface Human In Vitro Airway Tissue Model

Toxicological sciences, 2017-03, Vol.156 (1), p.14-24

2017

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Cigarette whole smoke solutions disturb mucin homeostasis in a human in vitro airway tissue model

Toxicology (Amsterdam), 2018-11, Vol.409, p.119-128

2018

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Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-related impurity

Mutation research. Genetic toxicology and environmental mutagenesis, 2021-08, Vol.868-869, p.503386-503386, Article 503386

2021

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Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay

Mutation research, 2020-10, Vol.858-860, p.503256, Article 503256

2020

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Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing

Archives of toxicology, 2024-06, Vol.98 (6), p.1919-1935

2024

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Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7th International Workshop on Genotoxicity Testing (IWGT)

Mutation research. Genetic toxicology and environmental mutagenesis, 2020-02, Vol.850-851, p.503135, Article 503135

2020

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Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

Nature reviews. Drug discovery, 2023-03, Vol.22 (3), p.165-166

2023

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Current and Future Application of Genetic Toxicity Assays: The Role and Value of In Vitro Mammalian Assays

Toxicological sciences, 2009-06, Vol.109 (2), p.172-179

2009

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Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives

The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup

Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay

The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment

Erythrocyte PIG‐A mutant frequencies in cancer patients receiving cisplatin

Transgenic animal models in toxicology: historical perspectives and future outlook

DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

The Genotoxicity of Acrylamide and Glycidamide in Big Blue Rats

Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes

Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines

In vivo genotoxicity of furan in F344 rats at cancer bioassay doses

International Pig-a gene mutation assay trial: Evaluation of transferability across 14 laboratories

Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adult gpt-delta transgenic mice

Tight junction disruption by cadmium in an in vitro human airway tissue model

Manifestation and persistence of Pig-a mutant red blood cells in C57BL/6 mice following single and split doses of N-ethyl-N-nitrosourea

Report on stage III Pig-a mutation assays using benzo[a]pyrene

Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, Aristolochic acids

Evaluating the Toxicity of Cigarette Whole Smoke Solutions in an Air-Liquid-Interface Human In Vitro Airway Tissue Model

Cigarette whole smoke solutions disturb mucin homeostasis in a human in vitro airway tissue model

Appropriate in vivo follow-up assays to an in vitro bacterial reverse mutation (Ames) test positive investigational drug candidate (active pharmaceutical ingredient), drug-related metabolite, or drug-related impurity

Molecular analysis of GPI-anchor biosynthesis pathway genes in rat strains used for the Pig-a gene mutation assay

Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing

Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7th International Workshop on Genotoxicity Testing (IWGT)

Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

Current and Future Application of Genetic Toxicity Assays: The Role and Value of In Vitro Mammalian Assays

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