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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2061-2065

2001

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Novel peptidomimetic hematoregulatory compounds

Bioorganic & medicinal chemistry letters, 2000-03, Vol.10 (6), p.531-534

2000

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Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 Endoribonuclease Activity

Molecular pharmacology, 2015-10, Vol.88 (6)

2015

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Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Antimicrobial Agents and Chemotherapy, 2002-10, Vol.46 (10), p.3118-3124

2002

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Simple method for controlling stereoselection in Mannich cyclization reactions of aldehydes

Journal of organic chemistry, 1993-12, Vol.58 (25), p.6947-6948

1993

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Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

Journal of medicinal chemistry, 2002-07, Vol.45 (15), p.3246-3256

2002

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New benzimidazoles as thrombopoietin receptor agonists

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1212-1216

2006

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New benzylidenethiazolidinediones as antibacterial agents

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (21), p.3771-3773

2003

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Combinatorial chemistry. Use of an intramolecular ruthenium catalyzed olefin/alkyne metathesis reaction in tandem with a Diels-Alder cycloaddition reaction to construct functionalized hexahydroisoindoles

Tetrahedron letters, 1998-09, Vol.39 (38), p.6815-6818

1998

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Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (8), p.1483-1486

2003

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Synthesis of substituted tetrahydropyridines by cyclizations of silicon-containing iminium ions

Tetrahedron, 1988, Vol.44 (13), p.3919-3930

1988

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The synthesis of a hematoregulatory agent based on HP-5B containing an effective, achiral cystine replacement

Bioorganic & medicinal chemistry letters, 1996-11, Vol.6 (22), p.2709-2712

1996

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ChemInform Abstract: Synthesis of Substituted Tetrahydropyridines by Cyclizations of Silicon‐Containing Iminium Ions

ChemInform, 1988-11, Vol.19 (45), p.no-no

1988

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ChemInform Abstract: Simple Method for Controlling Stereoselection in Mannich Cyclization Reactions of Aldehydes

ChemInform, 1994-04, Vol.25 (16), p.no-no

1994

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Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Cancer research (Chicago, Ill.), 2008-04, Vol.68 (7), p.2366-2374

2008

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Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors

ACS medicinal chemistry letters, 2020-02, Vol.11 (2), p.133-140

2020

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Aminofurazans as potent inhibitors of AKT kinase

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (5), p.1508-1511

2009

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Abstract 2919: Discovery of small-molecule compounds targeting c-MYC using a novel cell-based screen

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2919-2919

2018

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Abstract A044: The discovery of potent KAT6 inhibitors that demonstrate anti-tumor activity in preclinical models of ER+ breast cancer

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.A044-A044

2023

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Identification and Function of Disulfide Bridges in the Extracellular Domains of the Angiotensin II Type 2 Receptor

Biochemistry (Easton), 2001-07, Vol.40 (28), p.8369-8377

2001

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Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation

The Journal of pharmacology and experimental therapeutics, 2001-08, Vol.298 (2), p.665

2001

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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)

Novel peptidomimetic hematoregulatory compounds

Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 Endoribonuclease Activity

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Simple method for controlling stereoselection in Mannich cyclization reactions of aldehydes

Discovery of Aminopyridine-Based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI)

New benzimidazoles as thrombopoietin receptor agonists

New benzylidenethiazolidinediones as antibacterial agents

Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic

Combinatorial chemistry. Use of an intramolecular ruthenium catalyzed olefin/alkyne metathesis reaction in tandem with a Diels-Alder cycloaddition reaction to construct functionalized hexahydroisoindoles

Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists

Synthesis of substituted tetrahydropyridines by cyclizations of silicon-containing iminium ions

The synthesis of a hematoregulatory agent based on HP-5B containing an effective, achiral cystine replacement

ChemInform Abstract: Synthesis of Substituted Tetrahydropyridines by Cyclizations of Silicon‐Containing Iminium Ions

ChemInform Abstract: Simple Method for Controlling Stereoselection in Mannich Cyclization Reactions of Aldehydes

Discovery of 7‑Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro‑1H‑indol-5-yl)‑7H‑pyrrolo[2,3‑d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

Characterization of an Akt Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase

Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors

Aminofurazans as potent inhibitors of AKT kinase

Abstract 2919: Discovery of small-molecule compounds targeting c-MYC using a novel cell-based screen

Abstract A044: The discovery of potent KAT6 inhibitors that demonstrate anti-tumor activity in preclinical models of ER+ breast cancer

Identification and Function of Disulfide Bridges in the Extracellular Domains of the Angiotensin II Type 2 Receptor

Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation

Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1 H -indol-5-yl)-7 H -pyrrolo[2,3- d ]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

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