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Deep learning allows genome-scale prediction of Michaelis constants from structural features

PLoS biology, 2021-10, Vol.19 (10), p.e3001402-e3001402

2021

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Machine Learning Techniques for Predicting Crop Photosynthetic Capacity from Leaf Reflectance Spectra

Molecular plant, 2017-06, Vol.10 (6), p.878-890

2017

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Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

Nature communications, 2018-12, Vol.9 (1), p.5252-10, Article 5252

2018

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A biochemically-interpretable machine learning classifier for microbial GWAS

Nature communications, 2020-05, Vol.11 (1), p.2580-2580, Article 2580

2020

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Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers

Proceedings of the National Academy of Sciences - PNAS, 2020-09, Vol.117 (37), p.23182-23190

2020

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Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance

Nature communications, 2018-10, Vol.9 (1), p.4306-9, Article 4306

2018

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Modeling photosynthetic resource allocation connects physiology with evolutionary environments

Scientific reports, 2021-08, Vol.11 (1), p.15979-15979, Article 15979

2021

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The role of photorespiration during the evolution of C4 photosynthesis in the genus Flaveria

eLife, 2014-06, Vol.3, p.e02478-e02478

2014

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A generic avian physiologically-based kinetic (PBK) model and its application in three bird species

Environment international, 2022-11, Vol.169, p.107547-107547, Article 107547

2022

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Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

Nature communications, 2018-12, Vol.9 (1), p.5270-9, Article 5270

2018

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Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

BMC genomics, 2020-07, Vol.21 (1), p.514-514, Article 514

2020

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Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes

BMC bioinformatics, 2020-04, Vol.21 (1), p.162-162, Article 162

2020

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C4 photosynthesis evolution: the conditional Mt. Fuji

Current opinion in plant biology, 2016-06, Vol.31, p.149-154

Heckmann, David

2016

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Quantitative Morphometric, Physiological, and Metabolic Characteristics of Chickens and Mallards for Physiologically Based Kinetic Model Development

Frontiers in physiology, 2022-04, Vol.13, p.858283-858283

2022

Volltextzugriff (PDF)

BLISTER Regulates Polycomb-Target Genes, Represses Stress-Regulated Genes and Promotes Stress Responses in Arabidopsis thaliana

Frontiers in plant science, 2017-09, Vol.8, p.1530-1530

2017

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Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models

Frontiers in physiology, 2022-04, Vol.13, p.858386-858386

2022

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C sub(4) photosynthesis evolution: the conditional Mt. Fuji

Current opinion in plant biology, 2016-06, Vol.31, p.149-154

Heckmann, David

2016

Volltextzugriff (PDF)

Modelling metabolic evolution on phenotypic fitness landscapes: a case study on C4 photosynthesis

Biochemical Society transactions, 2015-12, Vol.43 (6), p.1172

Heckmann, David

2015

Volltextzugriff (PDF)

Predicting C4 Photosynthesis Evolution: Modular, Individually Adaptive Steps on a Mount Fuji Fitness Landscape

Cell, 2013-06, Vol.153 (7), p.1579-1588

2013

Volltextzugriff (PDF)

Reproductive toxicity in birds predicted by physiologically-based kinetics and bioenergetics modelling

The Science of the total environment, 2024-02, Vol.912, p.169096-169096, Article 169096

2024

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Combining genetic and evolutionary engineering to establish C 4 metabolism in C 3 plants

Journal of experimental botany, 2017-01, Vol.68 (2), p.117-125

2017

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Cellular responses to reactive oxygen species are predicted from molecular mechanisms

Proceedings of the National Academy of Sciences - PNAS, 2019-07, Vol.116 (28), p.14368-14373

2019

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Combining genetic and evolutionary engineering to establish C₄ metabolism in C₃ plants

Journal of experimental botany, 2017-01, Vol.68 (2), p.117-125

2017

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Energetic basis for bird ontogeny and egg-laying applied to the bobwhite quail

Conservation physiology, 2022-01, Vol.10 (1), p.1-coac063

2022

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Numerical computation of incomplete Lipschitz-Hankel integrals of the Hankel type for complex-valued arguments

Radio science, 2005-12, Vol.40 (6), p.RS6009-n/a

2005

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Deep learning allows genome-scale prediction of Michaelis constants from structural features

Machine Learning Techniques for Predicting Crop Photosynthetic Capacity from Leaf Reflectance Spectra

Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

A biochemically-interpretable machine learning classifier for microbial GWAS

Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers

Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance

Modeling photosynthetic resource allocation connects physiology with evolutionary environments

The role of photorespiration during the evolution of C4 photosynthesis in the genus Flaveria

A generic avian physiologically-based kinetic (PBK) model and its application in three bird species

Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates

Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

Adaptations of Escherichia coli strains to oxidative stress are reflected in properties of their structural proteomes

C4 photosynthesis evolution: the conditional Mt. Fuji

Quantitative Morphometric, Physiological, and Metabolic Characteristics of Chickens and Mallards for Physiologically Based Kinetic Model Development

BLISTER Regulates Polycomb-Target Genes, Represses Stress-Regulated Genes and Promotes Stress Responses in Arabidopsis thaliana

Quantitative Comparison of Avian and Mammalian Physiologies for Parameterization of Physiologically Based Kinetic Models

C sub(4) photosynthesis evolution: the conditional Mt. Fuji

Modelling metabolic evolution on phenotypic fitness landscapes: a case study on C4 photosynthesis

Predicting C4 Photosynthesis Evolution: Modular, Individually Adaptive Steps on a Mount Fuji Fitness Landscape

Reproductive toxicity in birds predicted by physiologically-based kinetics and bioenergetics modelling

Combining genetic and evolutionary engineering to establish C 4 metabolism in C 3 plants

Cellular responses to reactive oxygen species are predicted from molecular mechanisms

Combining genetic and evolutionary engineering to establish C₄ metabolism in C₃ plants

Energetic basis for bird ontogeny and egg-laying applied to the bobwhite quail

Numerical computation of incomplete Lipschitz-Hankel integrals of the Hankel type for complex-valued arguments

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