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Why do hubs tend to be essential in protein networks?

PLoS genetics, 2006-06, Vol.2 (6), p.e88-e88

2006

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Rapid Subfunctionalization Accompanied by Prolonged and Substantial Neofunctionalization in Duplicate Gene Evolution

Genetics (Austin), 2005-02, Vol.169 (2), p.1157-1164

2005

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Expression reduction in mammalian X chromosome evolution refutes Ohno’s hypothesis of dosage compensation

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (29), p.11752-11757

2012

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Mapping single-cell-resolution cell phylogeny reveals cell population dynamics during organ development

Nature methods, 2021-12, Vol.18 (12), p.1506-1514

2021

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Development of a high-fidelity Cas9-dependent adenine base editor (ABE) system for genome editing with high-fidelity Cas9 variants

Genes & diseases, 2023-05, Vol.10 (3), p.705-707

2023

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RNA sequencing shows no dosage compensation of the active X-chromosome

Nature genetics, 2010-12, Vol.42 (12), p.1043-1047

2010

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Toward a Molecular Understanding of Pleiotropy

Genetics (Austin), 2006-08, Vol.173 (4), p.1885-1891

2006

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Peroxiredoxin alleviates the fitness costs of imidacloprid resistance in an insect pest of rice

PLoS biology, 2021-04, Vol.19 (4), p.e3001190-e3001190

2021

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Biosynthetic energy cost for amino acids decreases in cancer evolution

Nature communications, 2018-10, Vol.9 (1), p.4124-15, Article 4124

2018

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Human A-to-I RNA editing SNP loci are enriched in GWAS signals for autoimmune diseases and under balancing selection

Genome Biology, 2020-11, Vol.21 (1), p.288-16, Article 288

2020

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Exploiting spatial dimensions to enable parallelized continuous directed evolution

Molecular systems biology, 2022-09, Vol.18 (9), p.e10934-n/a

2022

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Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

Nature genetics, 2010-03, Vol.42 (3), p.272-276

2010

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Reduced intrinsic DNA curvature leads to increased mutation rate

Genome Biology, 2018-09, Vol.19 (1), p.132-12, Article 132

2018

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Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes

Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6073), p.1235-1238

2012

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Measuring the evolutionary rate of protein-protein interaction

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (21), p.8725-8730

2011

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Insecticide resistance reduces the profitability of insect-resistant rice cultivars

Journal of advanced research, 2024-06, Vol.60, p.1-12

2024

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Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus

Viruses, 2022-09, Vol.14 (9), p.2065

2022

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Genetic incompatibility dampens hybrid fertility more than hybrid viability: yeast as a case study

PloS one, 2011-04, Vol.6 (4), p.e18341-e18341

2011

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A simple strategy for reducing false negatives in calling variants from single-cell sequencing data

PloS one, 2015-04, Vol.10 (4), p.e0123789-e0123789

2015

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The Convergent Cancer Evolution toward a Single Cellular Destination

Molecular biology and evolution, 2016-01, Vol.33 (1), p.4-12

2016

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Tree of life at two levels: from species to cell

Science bulletin, 2023-11, Vol.68 (21), p.2515-2518

2023

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Higher duplicability of less important genes in yeast genomes

Molecular biology and evolution, 2006-01, Vol.23 (1), p.144-151

2006

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The Biology Complicated by Genetic Analysis

Molecular biology and evolution, 2016-09, Vol.33 (9), p.2177-2181

He, Xionglei

2016

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On the growth of scientific knowledge: yeast biology as a case study

PLoS computational biology, 2009-03, Vol.5 (3), p.e1000320-e1000320

2009

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Reassessing the "duon" hypothesis of protein evolution

Molecular biology and evolution, 2015-04, Vol.32 (4), p.1056-1062

2015

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Why do hubs tend to be essential in protein networks?

Rapid Subfunctionalization Accompanied by Prolonged and Substantial Neofunctionalization in Duplicate Gene Evolution

Expression reduction in mammalian X chromosome evolution refutes Ohno’s hypothesis of dosage compensation

Mapping single-cell-resolution cell phylogeny reveals cell population dynamics during organ development

Development of a high-fidelity Cas9-dependent adenine base editor (ABE) system for genome editing with high-fidelity Cas9 variants

RNA sequencing shows no dosage compensation of the active X-chromosome

Toward a Molecular Understanding of Pleiotropy

Peroxiredoxin alleviates the fitness costs of imidacloprid resistance in an insect pest of rice

Biosynthetic energy cost for amino acids decreases in cancer evolution

Human A-to-I RNA editing SNP loci are enriched in GWAS signals for autoimmune diseases and under balancing selection

Exploiting spatial dimensions to enable parallelized continuous directed evolution

Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

Reduced intrinsic DNA curvature leads to increased mutation rate

Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes

Measuring the evolutionary rate of protein-protein interaction

Insecticide resistance reduces the profitability of insect-resistant rice cultivars

Predicting Egg Passage Adaptations to Design Better Vaccines for the H3N2 Influenza Virus

Genetic incompatibility dampens hybrid fertility more than hybrid viability: yeast as a case study

A simple strategy for reducing false negatives in calling variants from single-cell sequencing data

The Convergent Cancer Evolution toward a Single Cellular Destination

Tree of life at two levels: from species to cell

Higher duplicability of less important genes in yeast genomes

The Biology Complicated by Genetic Analysis

On the growth of scientific knowledge: yeast biology as a case study

Reassessing the "duon" hypothesis of protein evolution

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