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Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipin

Food and chemical toxicology, 2018-08, Vol.118, p.695-708

2018

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Chronic toxicity and carcinogenicity study of dietary gardenia blue in Sprague Dawley rats

Food and chemical toxicology, 2023-06, Vol.176, p.113734, Article 113734

2023

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Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids

Biomedicine & pharmacotherapy, 2021-10, Vol.142, p.112043, Article 112043

2021

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Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague–Dawley rats

Archives of toxicology, 2020-07, Vol.94 (7), p.2413-2421

2020

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Comparison of the fecal bacterial microbiota in mice, rats, and pigs after oral administration of alpha-glycosyl isoquercitrin

The Journal of Toxicological Sciences, 2024, Vol.49(4), pp.151-161

2024

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Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin

Food and chemical toxicology, 2015-09, Vol.83, p.283-292

2015

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Metronidazole enhances steatosis-related early-stage hepatocarcinogenesis in high fat diet-fed rats through DNA double-strand breaks and modulation of autophagy

Environmental science and pollution research international, 2022-01, Vol.29 (1), p.779-789

2022

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Ameliorating effect of postweaning exposure to antioxidant on disruption of hippocampal neurogenesis induced by developmental hypothyroidism in rats

The Journal of Toxicological Sciences, 2019, Vol.44(5), pp.357-372

2019

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Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential

Food and chemical toxicology, 2018-03, Vol.113, p.218-227

2018

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Twelve-month in utero safety assessment of gardenia blue, a natural food colorant

Journal of Toxicologic Pathology, 2023, Vol.36(3), pp.171-179

2023

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Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats

Toxicology letters, 2014-01, Vol.224 (1), p.64-72

2014

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Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats

Food and chemical toxicology, 2016-11, Vol.97, p.354-366

2016

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Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation

Food and chemical toxicology, 2017-02, Vol.100, p.103-114

2017

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Potential Effects of Alpha-Glycosyl Isoquercitrin on Memory by Altering the Gut Microbiota-Blood–Brain Axis in Mice

Journal of agricultural and food chemistry, 2023-11, Vol.71 (43), p.15991-16002

2023

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Chronic dietary toxicity and carcinogenicity studies of dammar resin in F344 rats

Archives of toxicology, 2018-12, Vol.92 (12), p.3565-3583

2018

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Role of pathology peer review in interpretation of the comet assay

Journal of Toxicologic Pathology, 2018, Vol.31(3), pp.155-161

2018

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Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats

Toxicology (Amsterdam), 2013-03, Vol.305, p.30-40

2013

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Continuous exposure to α-glycosyl isoquercitrin from developmental stage facilitates fear extinction learning in rats

Journal of functional foods, 2019-04, Vol.55, p.312-324

2019

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Differential impacts of mineralocorticoid receptor antagonist potassium canrenoate on liver and renal changes in high fat diet-mediated early hepatocarcinogenesis model rats

The Journal of Toxicological Sciences, 2018, Vol.43(10), pp.611-621

2018

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Lack of skin sensitization hazard potential for alpha-glycosyl isoquercitrin (AGIQ) utilizing the Local Lymph Node Assay

Toxicology reports, 2022-01, Vol.9, p.1291-1296

2022

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Utilizing novel telepathology system in preclinical studies and peer review

Journal of Toxicologic Pathology, 2018, Vol.31(4), pp.315-319

2018

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Continuous exposure to α-glycosyl isoquercitrin from developmental stages to adulthood is necessary for facilitating fear extinction learning in rats

Journal of Toxicologic Pathology, 2020, Vol.33(4), pp.247-263

2020

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Lack of preventive effect of maternal exposure to α-glycosyl isoquercitrin and α-lipoic acid on developmental hypothyroidism-induced aberrations of hippocampal neurogenesis in rat offspring

Journal of Toxicologic Pathology, 2019, Vol.32(3), pp.165-180

2019

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Magnesium stearate, a widely-used food additive, exhibits a lack of in vitro and in vivo genotoxic potential

Toxicology reports, 2017-01, Vol.4, p.554-559

2017

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Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 2017-01, Vol.69 (1), p.9-16

2017

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Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipin

Chronic toxicity and carcinogenicity study of dietary gardenia blue in Sprague Dawley rats

Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids

Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague–Dawley rats

Comparison of the fecal bacterial microbiota in mice, rats, and pigs after oral administration of alpha-glycosyl isoquercitrin

Genotoxicity evaluation of the flavonoid, myricitrin, and its aglycone, myricetin

Metronidazole enhances steatosis-related early-stage hepatocarcinogenesis in high fat diet-fed rats through DNA double-strand breaks and modulation of autophagy

Ameliorating effect of postweaning exposure to antioxidant on disruption of hippocampal neurogenesis induced by developmental hypothyroidism in rats

Comprehensive evaluation of the flavonol anti-oxidants, alpha-glycosyl isoquercitrin and isoquercitrin, for genotoxic potential

Twelve-month in utero safety assessment of gardenia blue, a natural food colorant

Ochratoxin A induces karyomegaly and cell cycle aberrations in renal tubular cells without relation to induction of oxidative stress responses in rats

Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats

Cilostazol and enzymatically modified isoquercitrin attenuate experimental colitis and colon cancer in mice by inhibiting cell proliferation and inflammation

Potential Effects of Alpha-Glycosyl Isoquercitrin on Memory by Altering the Gut Microbiota-Blood–Brain Axis in Mice

Chronic dietary toxicity and carcinogenicity studies of dammar resin in F344 rats

Role of pathology peer review in interpretation of the comet assay

Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats

Continuous exposure to α-glycosyl isoquercitrin from developmental stage facilitates fear extinction learning in rats

Differential impacts of mineralocorticoid receptor antagonist potassium canrenoate on liver and renal changes in high fat diet-mediated early hepatocarcinogenesis model rats

Lack of skin sensitization hazard potential for alpha-glycosyl isoquercitrin (AGIQ) utilizing the Local Lymph Node Assay

Utilizing novel telepathology system in preclinical studies and peer review

Continuous exposure to α-glycosyl isoquercitrin from developmental stages to adulthood is necessary for facilitating fear extinction learning in rats

Lack of preventive effect of maternal exposure to α-glycosyl isoquercitrin and α-lipoic acid on developmental hypothyroidism-induced aberrations of hippocampal neurogenesis in rat offspring

Magnesium stearate, a widely-used food additive, exhibits a lack of in vitro and in vivo genotoxic potential

Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats

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