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Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (13), p.6250-6259

2019

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Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.E9343-E9352

2018

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Engineering the Composition and Fate of Wild Populations with Gene Drive

Annual review of entomology, 2021-01, Vol.66 (1), p.407-434

2021

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Gene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (16), p.9013-9021

2020

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Split versions of Cleave and Rescue selfish genetic elements for measured self limiting gene drive

PLoS genetics, 2021-02, Vol.17 (2), p.e1009385-e1009385

2021

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Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila

Nature communications, 2016-11, Vol.7 (1), p.13100-11, Article 13100

2016

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Gene drive that results in addiction to a temperature-sensitive version of an essential gene triggers population collapse in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2021-12, Vol.118 (49), p.1-9

2021

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Gene drive-mediated population elimination for biodiversity conservation. When you come to a fork in the road, take it

Proceedings of the National Academy of Sciences - PNAS, 2022-12, Vol.119 (51), p.e2218020119-e2218020119

2022

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A Synthetic Gene Drive System for Local, Reversible Modification and Suppression of Insect Populations

Current biology, 2013-04, Vol.23 (8), p.671-677

2013

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Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails

Nature communications, 2024-08, Vol.15 (1), p.6665-12, Article 6665

2024

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Manipulating the Destiny of Wild Populations Using CRISPR

Annual review of genetics, 2023-11, Vol.57 (1), p.361-390

2023

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Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria

Nature communications, 2022-03, Vol.13 (1), p.1582-1582, Article 1582

2022

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Vectored gene delivery for lifetime animal contraception: Overview and hurdles to implementation

Theriogenology, 2018-05, Vol.112, p.63-74

2018

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Mapping a multiplexed zoo of mRNA expression

Development (Cambridge), 2016-10, Vol.143 (19), p.3632-3637

2016

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A drug-inducible sex-separation technique for insects

Nature communications, 2020-04, Vol.11 (1), p.2106-10, Article 2106

2020

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Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants

eLife, 2017-03, Vol.6

2017

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Caspase-dependent cell death in Drosophila

Annual review of cell and developmental biology, 2006-01, Vol.22 (1), p.623-650

2006

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Medusa: a novel gene drive system for confined suppression of insect populations

PloS one, 2014-07, Vol.9 (7), p.e102694-e102694

2014

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The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

Current biology, 2003-04, Vol.13 (9), p.790-795

2003

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The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector

G3 : genes - genomes - genetics, 2013-09, Vol.3 (9), p.1493-1509

2013

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Rules of the road for insect gene drive research and testing

Nature biotechnology, 2017-08, Vol.35 (8), p.716-718

2017

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

Nature, 2006-06, Vol.441 (7097), p.1162-1166

2006

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Pharmacokinetics of fluorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer thyrointegrin αvβ3 antagonist

Frontiers in pharmacology, 2022-11, Vol.13, p.902141-902141

2022

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Inactivation of Both foxo and reaper Promotes Long-Term Adult Neurogenesis in Drosophila

Current biology, 2010-04, Vol.20 (7), p.643-648

2010

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Confinement of gene drive systems to local populations: A comparative analysis

Journal of theoretical biology, 2012-02, Vol.294, p.153-171

2012

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Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive

Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs

Engineering the Composition and Fate of Wild Populations with Gene Drive

Gene drive and resilience through renewal with next generation Cleave and Rescue selfish genetic elements

Split versions of Cleave and Rescue selfish genetic elements for measured self limiting gene drive

Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila

Gene drive that results in addiction to a temperature-sensitive version of an essential gene triggers population collapse in Drosophila

Gene drive-mediated population elimination for biodiversity conservation. When you come to a fork in the road, take it

A Synthetic Gene Drive System for Local, Reversible Modification and Suppression of Insect Populations

Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails

Manipulating the Destiny of Wild Populations Using CRISPR

Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria

Vectored gene delivery for lifetime animal contraception: Overview and hurdles to implementation

Mapping a multiplexed zoo of mRNA expression

A drug-inducible sex-separation technique for insects

Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants

Caspase-dependent cell death in Drosophila

Medusa: a novel gene drive system for confined suppression of insect populations

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector

Rules of the road for insect gene drive research and testing

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

Pharmacokinetics of fluorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer thyrointegrin αvβ3 antagonist

Inactivation of Both foxo and reaper Promotes Long-Term Adult Neurogenesis in Drosophila

Confinement of gene drive systems to local populations: A comparative analysis

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